Open Access
Open access
SAGE
Natural Product Communications
,  volume 17 ,  issue 6 ,  pages 1934578X2211053

Ergostane-Type Sterols From Several Cordyceps Strains

Publication type: Journal Article
Publication date: 2022-06-24
SAGE
scimago Q3
wos Q4
SJR: 0.306
CiteScore: 2.6
Impact factor: 1.4
ISSN: 1934578X, 15559475
Drug Discovery
General Medicine
Pharmacology
Complementary and alternative medicine
Plant Science
Abstract

Ergosterol is an essential component for fungi, including entomopathogenic fungi like Cordyceps. Cordyceps has been used as a traditional medicine in Japan and China and possesses various unique ergostane-type sterols, those exhibit bioactivities. In this manuscript, we reported the isolation of 2 new ergostane-type sterols, 1 and 2 along with ten sterols (3-12) from 7 strains of Cordyceps related fungal strains, Cordyceps takaomontana NBRC 101754, Metarhizium owariense NBRC 33258, Polycephalomyces formosus NBRC 109994, Cordyceps tuberculata NBRC 106948, Cordyceps tenuipes NBRC 108997, Cordyceps sp. NBRC 106954, and Tolypocladium paradoxum NBRC 106958 collected fruiting bodies of Ophiocordyceps heteropoda. In addition, the antitrypanosomal activity and antimicrobial activity of isolates were tested to find 6 showed the antitrypanosomal activity, and the minimum inhibitory concentration (MIC) value was confirmed as 1.41 µg/mL. In the antimicrobial assay, the MIC value of 8 against methicillin-resistant Staphylococcus aureus was determined to be 3.1 µg/mL.

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GOST |
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GOST Copy
Yoneyama T. et al. Ergostane-Type Sterols From Several Cordyceps Strains // Natural Product Communications. 2022. Vol. 17. No. 6. p. 1934578X2211053.
GOST all authors (up to 50) Copy
Yoneyama T., Takahashi H., Grudniewska A., Ban S., Umeyama A., Noji M. Ergostane-Type Sterols From Several Cordyceps Strains // Natural Product Communications. 2022. Vol. 17. No. 6. p. 1934578X2211053.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1177/1934578x221105363
UR - https://journals.sagepub.com/doi/10.1177/1934578X221105363
TI - Ergostane-Type Sterols From Several Cordyceps Strains
T2 - Natural Product Communications
AU - Yoneyama, Tatsuro
AU - Takahashi, Hiroki
AU - Grudniewska, Aleksandra
AU - Ban, Sayaka
AU - Umeyama, Akemi
AU - Noji, Masaaki
PY - 2022
DA - 2022/06/24
PB - SAGE
SP - 1934578X2211053
IS - 6
VL - 17
SN - 1934-578X
SN - 1555-9475
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2022_Yoneyama,
author = {Tatsuro Yoneyama and Hiroki Takahashi and Aleksandra Grudniewska and Sayaka Ban and Akemi Umeyama and Masaaki Noji},
title = {Ergostane-Type Sterols From Several Cordyceps Strains},
journal = {Natural Product Communications},
year = {2022},
volume = {17},
publisher = {SAGE},
month = {jun},
url = {https://journals.sagepub.com/doi/10.1177/1934578X221105363},
number = {6},
pages = {1934578X2211053},
doi = {10.1177/1934578x221105363}
}
MLA
Cite this
MLA Copy
Yoneyama, Tatsuro, et al. “Ergostane-Type Sterols From Several Cordyceps Strains.” Natural Product Communications, vol. 17, no. 6, Jun. 2022, p. 1934578X2211053. https://journals.sagepub.com/doi/10.1177/1934578X221105363.