Gold embedded chitosan nanoparticles with cell membrane mimetic polymer coating for pH-sensitive controlled drug release and cellular fluorescence imaging
Тип публикации: Journal Article
Дата публикации: 2020-08-27
scimago Q3
wos Q3
БС2
SJR: 0.525
CiteScore: 6.0
Impact factor: 2.5
ISSN: 08853282, 15308022
PubMed ID:
32854570
Biomaterials
Biomedical Engineering
Краткое описание
In this work, gold embedded chitosan nanoparticles (Au@CS NPs) were fabricated by a one-pot method. The benzaldehyde-terminated poly[(2-methacryloyloxy) ethyl phosphorylcholine] (PMPC) was applied to modification of the gold doped chitosan nanoparticles. The obtained Au@CS-PMPC NPs had the diameter of 135 nm with a narrow distribution. The size of the Au@CS-PMPC NPs, as well as the size of the embedded gold NPs, might be well-controlled by adjusting the feeding ratio between chitosan and HAuCl4. Furthermore, the Au@CS-PMPC NPs showed increased colloidal stability, high drug loading content, pH-responsive drug release, excellent biocompatibility and bright fluorescence emission. The results demonstrated that Au@CS-PMPC NPs showed a great potential for tumor therapy via the combination advantages of pH-sensitive controlled drug release and cellular fluorescence imaging.
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ГОСТ
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Ma K. et al. Gold embedded chitosan nanoparticles with cell membrane mimetic polymer coating for pH-sensitive controlled drug release and cellular fluorescence imaging // Journal of Biomaterials Applications. 2020. Vol. 35. No. 7. pp. 857-868.
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Ma K., Cheng Y., Wei X., Chen D., Zhao X., Jia P. Gold embedded chitosan nanoparticles with cell membrane mimetic polymer coating for pH-sensitive controlled drug release and cellular fluorescence imaging // Journal of Biomaterials Applications. 2020. Vol. 35. No. 7. pp. 857-868.
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TY - JOUR
DO - 10.1177/0885328220952594
UR - https://doi.org/10.1177/0885328220952594
TI - Gold embedded chitosan nanoparticles with cell membrane mimetic polymer coating for pH-sensitive controlled drug release and cellular fluorescence imaging
T2 - Journal of Biomaterials Applications
AU - Ma, Ke
AU - Cheng, Yongbin
AU - Wei, Xinran
AU - Chen, Daijun
AU - Zhao, Xiaoli
AU - Jia, Pengxiang
PY - 2020
DA - 2020/08/27
PB - SAGE
SP - 857-868
IS - 7
VL - 35
PMID - 32854570
SN - 0885-3282
SN - 1530-8022
ER -
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BibTex (до 50 авторов)
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@article{2020_Ma,
author = {Ke Ma and Yongbin Cheng and Xinran Wei and Daijun Chen and Xiaoli Zhao and Pengxiang Jia},
title = {Gold embedded chitosan nanoparticles with cell membrane mimetic polymer coating for pH-sensitive controlled drug release and cellular fluorescence imaging},
journal = {Journal of Biomaterials Applications},
year = {2020},
volume = {35},
publisher = {SAGE},
month = {aug},
url = {https://doi.org/10.1177/0885328220952594},
number = {7},
pages = {857--868},
doi = {10.1177/0885328220952594}
}
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MLA
Скопировать
Ma, Ke, et al. “Gold embedded chitosan nanoparticles with cell membrane mimetic polymer coating for pH-sensitive controlled drug release and cellular fluorescence imaging.” Journal of Biomaterials Applications, vol. 35, no. 7, Aug. 2020, pp. 857-868. https://doi.org/10.1177/0885328220952594.