volume 35 issue 7 pages 857-868

Gold embedded chitosan nanoparticles with cell membrane mimetic polymer coating for pH-sensitive controlled drug release and cellular fluorescence imaging

Publication typeJournal Article
Publication date2020-08-27
scimago Q3
wos Q3
SJR0.525
CiteScore6.0
Impact factor2.5
ISSN08853282, 15308022
Biomaterials
Biomedical Engineering
Abstract

In this work, gold embedded chitosan nanoparticles (Au@CS NPs) were fabricated by a one-pot method. The benzaldehyde-terminated poly[(2-methacryloyloxy) ethyl phosphorylcholine] (PMPC) was applied to modification of the gold doped chitosan nanoparticles. The obtained Au@CS-PMPC NPs had the diameter of 135 nm with a narrow distribution. The size of the Au@CS-PMPC NPs, as well as the size of the embedded gold NPs, might be well-controlled by adjusting the feeding ratio between chitosan and HAuCl4. Furthermore, the Au@CS-PMPC NPs showed increased colloidal stability, high drug loading content, pH-responsive drug release, excellent biocompatibility and bright fluorescence emission. The results demonstrated that Au@CS-PMPC NPs showed a great potential for tumor therapy via the combination advantages of pH-sensitive controlled drug release and cellular fluorescence imaging.

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GOST |
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GOST Copy
Ma K. et al. Gold embedded chitosan nanoparticles with cell membrane mimetic polymer coating for pH-sensitive controlled drug release and cellular fluorescence imaging // Journal of Biomaterials Applications. 2020. Vol. 35. No. 7. pp. 857-868.
GOST all authors (up to 50) Copy
Ma K., Cheng Y., Wei X., Chen D., Zhao X., Jia P. Gold embedded chitosan nanoparticles with cell membrane mimetic polymer coating for pH-sensitive controlled drug release and cellular fluorescence imaging // Journal of Biomaterials Applications. 2020. Vol. 35. No. 7. pp. 857-868.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1177/0885328220952594
UR - https://doi.org/10.1177/0885328220952594
TI - Gold embedded chitosan nanoparticles with cell membrane mimetic polymer coating for pH-sensitive controlled drug release and cellular fluorescence imaging
T2 - Journal of Biomaterials Applications
AU - Ma, Ke
AU - Cheng, Yongbin
AU - Wei, Xinran
AU - Chen, Daijun
AU - Zhao, Xiaoli
AU - Jia, Pengxiang
PY - 2020
DA - 2020/08/27
PB - SAGE
SP - 857-868
IS - 7
VL - 35
PMID - 32854570
SN - 0885-3282
SN - 1530-8022
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2020_Ma,
author = {Ke Ma and Yongbin Cheng and Xinran Wei and Daijun Chen and Xiaoli Zhao and Pengxiang Jia},
title = {Gold embedded chitosan nanoparticles with cell membrane mimetic polymer coating for pH-sensitive controlled drug release and cellular fluorescence imaging},
journal = {Journal of Biomaterials Applications},
year = {2020},
volume = {35},
publisher = {SAGE},
month = {aug},
url = {https://doi.org/10.1177/0885328220952594},
number = {7},
pages = {857--868},
doi = {10.1177/0885328220952594}
}
MLA
Cite this
MLA Copy
Ma, Ke, et al. “Gold embedded chitosan nanoparticles with cell membrane mimetic polymer coating for pH-sensitive controlled drug release and cellular fluorescence imaging.” Journal of Biomaterials Applications, vol. 35, no. 7, Aug. 2020, pp. 857-868. https://doi.org/10.1177/0885328220952594.