Open Access
Drimendiol, A Drimane Sesquiterpene with Quorum Sensing Inhibition Activity
Cristian Paz
1
,
Gerardo Cárcamo
2
,
Mario Silva
1
,
Jose Becerra
1
,
Homero Urrutia
2
,
Katherine Sossa
3
Publication type: Journal Article
Publication date: 2013-02-01
scimago Q3
wos Q4
SJR: 0.306
CiteScore: 2.6
Impact factor: 1.4
ISSN: 1934578X, 15559475
Drug Discovery
General Medicine
Pharmacology
Complementary and alternative medicine
Plant Science
Abstract
Quorum sensing (QS) is a regulatory mechanism that enables bacteria to make collective decisions such as an increase in virulence factors and biofilm production. Inhibitors of QS are important research tools in the discovery of new potential anti-bacterial agents. Polygodial, drimenol and drimendiol are drimane sesquiterpenoids isolated from Drimys winteri, a Chilean native tree. Their QS activity, when tested on Chromobacterium violaceum ATCC 12472, showed that drimendiol is an inhibitor of QS, decreasing violaceine production in C. violaceum and decreasing biofilm formation of Pseudomonas syringae strains. Consequently it increased the biocide effects of CuSO4 on biofilms of P. syringae.
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10
Total citations:
10
Citations from 2025:
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(20%)
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MLA
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GOST
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Paz C. et al. Drimendiol, A Drimane Sesquiterpene with Quorum Sensing Inhibition Activity // Natural Product Communications. 2013. Vol. 8. No. 2. p. 1934578X1300800.
GOST all authors (up to 50)
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Paz C., Cárcamo G., Silva M., Becerra J., Urrutia H., Sossa K. Drimendiol, A Drimane Sesquiterpene with Quorum Sensing Inhibition Activity // Natural Product Communications. 2013. Vol. 8. No. 2. p. 1934578X1300800.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1177/1934578x1300800201
UR - https://doi.org/10.1177/1934578x1300800201
TI - Drimendiol, A Drimane Sesquiterpene with Quorum Sensing Inhibition Activity
T2 - Natural Product Communications
AU - Paz, Cristian
AU - Cárcamo, Gerardo
AU - Silva, Mario
AU - Becerra, Jose
AU - Urrutia, Homero
AU - Sossa, Katherine
PY - 2013
DA - 2013/02/01
PB - SAGE
SP - 1934578X1300800
IS - 2
VL - 8
SN - 1934-578X
SN - 1555-9475
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2013_Paz,
author = {Cristian Paz and Gerardo Cárcamo and Mario Silva and Jose Becerra and Homero Urrutia and Katherine Sossa},
title = {Drimendiol, A Drimane Sesquiterpene with Quorum Sensing Inhibition Activity},
journal = {Natural Product Communications},
year = {2013},
volume = {8},
publisher = {SAGE},
month = {feb},
url = {https://doi.org/10.1177/1934578x1300800201},
number = {2},
pages = {1934578X1300800},
doi = {10.1177/1934578x1300800201}
}
Cite this
MLA
Copy
Paz, Cristian, et al. “Drimendiol, A Drimane Sesquiterpene with Quorum Sensing Inhibition Activity.” Natural Product Communications, vol. 8, no. 2, Feb. 2013, p. 1934578X1300800. https://doi.org/10.1177/1934578x1300800201.