Open Access

Journal of Intensive Care

, volume 9 , issue 1 , publication number 53

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)

Moritoki Egi ¹

Hiroshi Ogura ²

Tomoaki Yatabe ³

Kazuaki Atagi ⁴

Inoue Shigeaki ⁵

Toshiaki Iba ⁶

Yasuyuki Kakihana ⁷

Tatsuya Kawasaki ⁸

Shigeki Kushimoto ⁹

Yasuhiro Kuroda ¹⁰

Joji Kotani ¹¹

Nobuaki Shime ¹²

Takumi Taniguchi ¹³

Ryosuke Tsuruta ¹⁴

Kent Doi ¹⁵

MATSUYUKI DOI ¹⁶

Taka-aki Nakada ¹⁷

Masaki Nakane ¹⁸

Seitaro Fujishima ¹⁹

Naoto Hosokawa ²⁰

Yoshiki Masuda ²¹

Asako Matsushima ²²

Naoyuki Matsuda ²³

Kazuma Yamakawa ²⁴

Yoshitaka Hara ³

Masaaki Sakuraya ²⁵

Shinichiro Ohshimo ¹²

Yoshitaka Aoki ¹⁶

Mai Inada ²⁶

Yutaka Umemura ²⁷

Yusuke Kawai ²⁸

Yutaka Kondo ²⁹

Hiroki Saito ³⁰

Shunsuke Taito ³¹

Chikashi Takeda ³²

Takero Terayama ³³

Hideo Tohira ³⁴

Hideki HASHIMOTO ³⁵

Kei Hayashida ³⁶

Toru Hifumi ³⁷

Tomoya Hirose ³⁸

Tatsuma Fukuda ³⁹

Tomoko Fujii ⁴⁰

Shinya Miura ⁴¹

Hideto Yasuda ⁴²

Toshikazu Abe ⁴³

Kohkichi Andoh ⁴⁴

Yuki Iida ⁴⁵

Tadashi ISHIHARA ²⁹

KENTARO IDE ⁴⁶

Kenta Ito ⁴⁷

Yusuke Ito ⁴⁸

Yu Inata ⁴⁹

Akemi Utsunomiya ⁵⁰

Takeshi Unoki ⁵¹

Koji Endo ⁵²

Akira Ouchi ⁵³

Masayuki Ozaki ⁵⁴

Satoshi Ono ⁵⁵

Morihiro Katsura ⁵⁶

Atsushi Kawaguchi ⁵⁷

Yusuke Kawamura ⁵⁸

Daisuke Kudo ⁹

Kenji KUBO ⁵⁹

Kiyoyasu Kurahashi ⁶⁰

Hideaki Sakuramoto ⁵³

Akira Shimoyama ⁴²

TAKESHI SUZUKI ⁶¹

Shusuke Sekine ⁶²

Motohiro Sekino ⁶³

Nozomi Takahashi ¹⁷

Sei Takahashi ⁶⁴

Hiroshi Takahashi ⁶⁵

Takashi Tagami ⁶⁶

Goro Tajima ⁶⁷

Hiroomi Tatsumi ²¹

Masanori TANI ⁶⁸

Asuka Tsuchiya ⁶⁹

Yusuke Tsutsumi ⁶⁹

Takaki Naito ⁷⁰

Masaharu Nagae ⁷¹

Ichiro Nagasawa ⁷²

Kensuke Nakamura ⁷³

Tetsuro Nishimura ⁷⁴

Shin Nunomiya ⁷⁵

Yasuhiro Norisue ⁷⁶

Satoru Hashimoto ⁷⁷

Daisuke Hasegawa ³

Junji Hatakeyama ⁷⁸

Naoki HARA ⁷⁹

Naoki Higashibeppu ⁸⁰

Nana Furushima ⁸¹

Hirotaka Furusono ⁸²

Yujiro Matsuishi ⁸³

Tasuku Matsuyama ⁸⁴

Yusuke Minematsu ⁸⁵

Ryoichi Miyashita ⁸⁶

Yuji Miyatake ⁸⁷

Megumi Moriyasu ⁸⁸

Toru Yamada ⁸⁹

Hiroyuki Yamada ⁹⁰

Ryo Yamamoto ⁹¹

Takeshi Yoshida ⁹²

Yuhei Yoshida ⁹³

Jumpei Yoshimura ²⁷

Ryuichi Yotsumoto ⁹⁴

Hiroshi Yonekura ⁹⁵

Takeshi Wada ⁹⁶

Eizo Watanabe ⁹⁷

Makoto AOKI ⁹⁸

Hideki Asai ⁹⁹

Takakuni ABE ¹⁰⁰

Yutaka IGARASHI ¹⁰¹

Naoya Iguchi ¹⁰²

Masami Ishikawa ¹⁰³

Go Ishimaru ¹⁰⁴

Shutaro Isokawa ³⁷

Ryuta ITAKURA ¹⁰⁵

Hisashi Imahase ¹⁰⁶

Haruki Imura ^{107, 108}

Takashi Irinoda ¹⁰⁹

Kenji Uehara ¹¹⁰

Noritaka Ushio ¹¹¹

Takeshi Umegaki ¹¹²

Yuko Egawa ¹¹³

Yuki Enomoto ¹¹⁴

Kohei Ota ¹²

Yoshifumi Ohchi ¹⁰⁰

Takanori Ohno ¹¹⁵

Hiroyuki Ohbe ¹¹⁶

Kazuyuki Oka ¹¹⁷

Nobunaga Okada ⁸⁴

Yohei Okada ¹¹⁸

Hiromu Okano ¹¹⁹

JUN OKAMOTO ¹²⁰

Hiroshi Okuda ¹²¹

Takayuki Ogura ¹²²

Yu Onodera ¹²³

Yuhta Oyama ¹²⁴

Motoshi KAINUMA ¹²⁵

Eisuke Kako ¹²⁶

Masahiro Kashiura ⁴²

Hiromi KATO ¹⁶

Akihiro Kanaya ¹²⁷

Tadashi Kaneko ¹²⁸

Keita Kanehata ¹¹¹

Ken-ichi Kano ¹²⁹

Hiroyuki Kawano ¹³⁰

Kazuya Kikutani ¹²

Hitoshi Kikuchi ¹³¹

Takahiro Kido ¹³²

Sho Kimura ⁶⁸

Hiroyuki Koami ¹³³

Daisuke KOBASHI ¹¹¹

Iwao SAIKI ⁶²

Masahito Sakai ¹³⁴

Ayaka Sakamoto ¹³⁵

Tetsuya SATO ¹⁰⁹

Yasuhiro Shiga ¹³⁶

Manabu Shimoto ¹¹⁸

Shinya Shimoyama ¹³⁷

Tomohisa Shoko ¹³⁸

Yoh Sugawara ¹³⁹

Atsunori Sugita ¹⁴⁰

Satoshi Suzuki ¹⁴¹

Yuji Suzuki ¹⁶

Tomohiro Suhara ¹⁴²

Kenji Sonota ¹⁴³

Shuhei Takauji ¹⁴⁴

Kohei Takashima ⁴⁶

Sho Takahashi ¹⁴⁵

Yoko Takahashi ¹⁴⁶

Jun Takeshita ¹⁴⁷

Yuuki Tanaka ¹⁴⁸

Akihito Tampo ¹⁴⁴

Taichiro Tsunoyama ¹⁴⁹

Kenichi Tetsuhara ¹⁵⁰

Kentaro Tokunaga ¹⁵¹

Yoshihiro Tomioka ¹⁵²

Kentaro Tomita ¹⁵³

Naoki Tominaga ¹⁰¹

Mitsunobu Toyosaki ⁹¹

Yukitoshi Toyoda ¹⁵⁴

Hiromichi Naito ¹⁵⁵

Isao Nagata ¹⁵⁶

Tadashi Nagato ¹⁵⁷

Yoshimi Nakamura ¹⁵⁸

Yuki Nakamori ⁹⁵

Isao Nahara ¹⁵⁹

Hiromu Naraba ⁷³

Chihiro Narita ¹⁶⁰

Norihiro Nishioka ¹⁶¹

Tomoya Nishimura ¹¹¹

Kei Nishiyama ¹⁶²

Tomohisa Nomura ¹⁶³

Taiki Haga ¹⁶⁴

Yoshihiro Hagiwara ¹⁶⁵

Katsuhiko HASHIMOTO ¹⁶⁶

Takeshi Hatachi ⁴⁹

Toshiaki Hamasaki ¹⁶⁷

Takuya Hayashi ⁶⁸

Minoru Hayashi ¹²⁹

Atsuki Hayamizu ¹⁶⁸

Go Haraguchi ¹⁶⁹

Yohei Hirano ²⁹

Ryo Fujii ¹⁷⁰

Motoki Fujita ¹⁴

Naoyuki Fujimura ¹⁷¹

Hiraku Funakoshi ⁷⁶

Masahito Horiguchi ¹⁷²

Jun Maki ¹⁷³

Naohisa Masunaga ¹⁷⁴

Yosuke Matsumura ¹⁷⁵

Takuya Mayumi ¹⁷⁶

Keisuke Minami ¹⁷⁷

Yuya Miyazaki ¹⁷⁸

Kazuyuki Miyamoto ¹⁷⁹

Teppei Murata ¹⁸⁰

Machi Yanai ¹⁸¹

Takao Yano ¹⁸²

Kohei Yamada ¹⁸³

Naoki Yamada ¹⁸⁴

Tomonori Yamamoto ⁴

Shodai Yoshihiro ¹⁸⁵

Hiroshi Tanaka ²⁹

Osamu Nishida ³

Hide authors affiliations Show authors affiliations: 185 affiliations

Department of Surgery Related, Division of Anesthesiology, Kobe University Graduate School of Medicine, Kobe, Japan |

Department of Traumatology and Acute Critical Medicine, Osaka University Medical School, Osaka, Japan |

Department of Anesthesiology and Critical Care Medicine, Fujita Health University School of Medicine, Toyoake, Japan |

⁴

Department of Intensive Care Unit, Nara Prefectural General Medical Center, Nara, Japan |

⁵

Department of Disaster and Emergency Medicine, Kobe University Graduate School of Medicine, Kobe, Japan |

⁶

Department of Emergency and Disaster Medicine, Juntendo University, Tokyo, Japan |

⁷

Department of Emergency and Intensive Care Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan |

⁸

Department of Pediatric Critical Care, Shizuoka Children’s Hospital, Shizuoka, Japan |

⁹

Division of Emergency and Critical Care Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan |

¹⁰

Department of Emergency, Disaster, and Critical Care Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan |

¹¹

Department of Surgery Related, Division of Disaster and Emergency Medicine, Kobe University Graduate School of Medicine, Kobe, Japan |

¹²

Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan |

¹³

Department of Anesthesiology and Intensive Care Medicine, Kanazawa University, Kanazawa, Japan |

¹⁴

Acute and General Medicine, Yamaguchi University Graduate School of Medicine, Ube, Japan |

¹⁵

Department of Acute Medicine, The University of Tokyo, Tokyo, Japan |

¹⁶

Department of Anesthesiology and Intensive Care Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan |

¹⁷

Department of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine, Chiba, Japan |

¹⁸

Department of Emergency and Critical Care Medicine, Yamagata University Hospital, Yamagata, Japan |

¹⁹

Center for General Medicine Education, Keio University School of Medicine, Tokyo, Japan |

²⁰

Department of Infectious Diseases, Kameda Medical Center, Kamogawa, Japan |

²¹

Department of Intensive Care Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan |

²²

Department of Advancing Acute Medicine, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan |

²³

Department of Emergency and Critical Care Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan |

²⁴

Department of Emergency Medicine, Osaka Medical College, Osaka, Japan |

²⁵

Department of Emergency and Intensive Care Medicine, JA Hiroshima General Hospital, Hatsukaichi, Japan |

²⁶

Member of Japanese Association for Acute Medicine, Tokyo, Japan |

²⁷

Division of Trauma and Surgical Critical Care, Osaka General Medical Center, Osaka, Japan |

²⁸

Department of Nursing, Fujita Health University Hospital, Toyoake, Japan |

²⁹

Department of Emergency and Critical Care Medicine, Juntendo University Urayasu Hospital, Urayasu, Japan |

³⁰

Department of Emergency and Critical Care Medicine, St. Marianna University School of Medicine, Yokohama City Seibu Hospital, Yokohama, Japan |

³¹

Division of Rehabilitation, Department of Clinical Support and Practice, Hiroshima University Hospital, Hiroshima, Japan |

³²

Department of Anesthesia, Kyoto University Hospital, Kyoto, Japan |

³³

Department of Psychiatry, School of Medicine, National Defense Medical College, Tokorozawa, Japan |

³⁴

Curtin university, Perth, Australia |

³⁵

Department of Emergency and Critical Care Medicine/Infectious Disease, Hitachi General Hospital, Hitachi, Japan |

³⁶

The Feinstein Institute for Medical Research, Manhasset, USA |

³⁷

Department of Emergency and Critical Care Medicine, St. Luke’s International Hospital, Tokyo, Japan |

³⁸

Emergency and Critical Care Medical Center, Osaka Police Hospital, Osaka, Japan |

³⁹

Department of Emergency and Critical Care Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan |

⁴⁰

Intensive Care Unit, Jikei University Hospital, Tokyo, Japan |

⁴¹

The Royal Children’s Hospital Melbourne, Melbourne, Australia |

⁴²

Department of Emergency and Critical Care Medicine, Jichi Medical University Saitama Medical Center, Saitama, Japan |

⁴³

Department of Emergency and Critical Care Medicine, Tsukuba Memorial Hospital, Tsukuba, Japan |

⁴⁴

Division of Anesthesiology, Division of Intensive Care, Division of Emergency and Critical Care, Sendai City Hospital, Sendai, Japan |

⁴⁵

Department of Physical Therapy, School of Health Sciences, Toyohashi SOZO University, Toyohashi, Japan |

⁴⁶

Critical Care Medicine, National Center for Child Health and Development, Tokyo, Japan |

⁴⁷

Department of General Pediatrics, Aichi Children’s Health and Medical Center, Obu, Japan |

⁴⁸

Department of Infectious Disease, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Japan |

⁴⁹

Department of Intensive Care Medicine, Osaka Women’s and Children’s Hospital, Izumi, Japan |

⁵⁰

Human Health Science, Graduate school of Medicine, Kyoto University, Kyoto, Japan |

⁵¹

Department of Acute and Critical Care Nursing, School of Nursing, Sapporo City University, Sapporo, Japan |

⁵²

Department of Pharmacoepidemiology, Kyoto University Graduate School of Medicine and Public Health, Kyoto, Japan |

⁵³

College of Nursing, Ibaraki Christian University, Hitachi, Japan |

⁵⁴

Department of Emergency and Critical Care Medicine, Komaki City Hospital, Komaki, Japan |

⁵⁵

Gastroenterological Center, Shinkuki General Hospital, Kuki, Japan |

⁵⁶

Department of Surgery, Okinawa Chubu Hospital, Uruma, Japan |

⁵⁷

CHU Sainte Justines, University of Montreal, Montreal, Canada |

⁵⁸

Department of Rehabilitation, Showa General Hospital, Tokyo, Japan |

⁵⁹

Department of Emergency Medicine and Department of Infectious Diseases, Japanese Red Cross Wakayama Medical Center, Wakayama, Japan |

⁶⁰

Department of Anesthesiology and Intensive Care Medicine, International University of Health and Welfare School of Medicine, Narita, Japan |

⁶¹

Department of Anesthesiology, Tokai University School of Medicine, Isehara, Japan |

⁶²

Department of Anesthesiology, Tokyo Medical University, Tokyo, Japan |

⁶³

Division of intensive care, Nagasaki University Hospital, Nagasaki, Japan |

⁶⁴

Center for Innovative Research for Communities and Clinical Excellence (CiRC2LE), Fukushima Medical University, Fukushima, Japan |

⁶⁵

Department of Cardiology, Steel Memorial Muroran Hospital, Muroran, Japan |

⁶⁶

Department of Emergency and Critical Care Medicine, Nippon Medical School Musashi Kosugi Hospital, Kawasaki, Japan |

⁶⁷

Nagasaki University Hospital Acute and Critical Care Center, Nagasaki, Japan |

⁶⁸

Division of Critical Care Medicine, Saitama Children’s Medical Center, Saitama, Japan |

⁶⁹

Department of Emergency and Critical Care Medicine, National Hospital Organization Mito Medical Center, Ibaraki, Japan |

⁷⁰

Department of Emergency and Critical Care Medicine, St. Marianna University School of Medicine, Kawasaki, Japan |

⁷¹

Department of Intensive Care Medicine, Kobe University Hospital, Kobe, Japan |

⁷²

School of Medicine, Tokai University, Isehara, Japan |

⁷³

Department of Emergency and Critical Care Medicine, Hitachi General Hospital, Hitachi, Japan |

⁷⁴

Department of Traumatology and Critical Care Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan |

⁷⁵

Department of Anesthesiology and Intensive Care Medicine, Division of Intensive Care, Jichi Medical University School of Medicine, Shimotsuke, Japan |

⁷⁶

Department of Emergency and Critical Care Medicine, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, Japan |

⁷⁷

Department of Anesthesiology and Intensive Care Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan |

⁷⁸

Department of Emergency and Critical Care Medicine, National Hospital Organization Tokyo Medical Center, Tokyo, Japan |

⁷⁹

Department of Pharmacy, Yokohama Rosai Hospital, Yokohama, Japan |

⁸⁰

Department of Anesthesiology and Nutrition Support Team, Kobe City Medical Center General Hospital, Kobe City Hospital Organization, Kobe, Japan |

⁸¹

Department of anesthesiology, Kobe University Hospital, Kobe, Japan |

⁸²

Department of Rehabilitation, University of Tsukuba Hospital/Exult Co., Ltd., Tsukuba, Japan |

⁸³

Doctoral program in Clinical Sciences. Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan |

⁸⁴

Department of Emergency Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan |

⁸⁵

Department of Clinical Engineering, Osaka University Hospital, Suita, Japan |

⁸⁶

Department of Intensive Care Medicine, Showa University School of Medicine, Tokyo, Japan |

⁸⁷

Department of Clinical Engineering, Kakogawa Central City Hospital, Kakogawa, Japan |

⁸⁸

Division of Respiratory Care and Rapid Response System, Intensive Care Center, Kitasato University Hospital, Sagamihara, Japan |

⁸⁹

Department of Nursing, Toho University Omori Medical Center, Tokyo, Japan |

⁹⁰

Department of Primary Care and Emergency Medicine, Kyoto University Hospital, Kyoto, Japan |

⁹¹

Department of Emergency and Critical Care Medicine, Keio University school of medicine, Tokyo, Japan |

⁹²

Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, Suita, Japan |

⁹³

Nursing Department, Osaka General Medical Center, Osaka, Japan |

⁹⁴

Toho University Omori Medical Center, Tokyo, Japan |

⁹⁵

Department of Clinical Anesthesiology, Mie University Hospital, Tsu, Japan |

⁹⁶

Department of Anesthesiology and Critical Care Medicine, Division of Acute and Critical Care Medicine, Hokkaido University Faculty of Medicine, Sapporo, Japan |

⁹⁷

Department of Emergency and Critical Care Medicine, Eastern Chiba Medical Center, Togane, Japan |

⁹⁸

Department of Emergency Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan |

⁹⁹

Department of Emergency and Critical Care Medicine, Nara Medical University, Kashihara, Japan |

¹⁰⁰

Department of Anesthesiology and Intensive Care, Oita University Hospital, Yufu, Japan |

¹⁰¹

Department of Emergency and Critical Care Medicine, Nippon Medical School Hospital, Tokyo, Japan |

¹⁰²

Department of Anesthesiology and Intensive Care Medicine, Graduate School of Medicine, Osaka University, Suita, Japan |

¹⁰³

Department of Anesthesiology, Emergency and Critical Care Medicine, Kure Kyosai Hospital, Kure, Japan |

¹⁰⁴

Department of General Internal Medicine, Soka Municipal Hospital, Soka, Japan |

¹⁰⁵

Department of Emergency and Critical Care Medicine, Tokyo Metropolitan Children’s Medical Center, Tokyo, Japan |

¹⁰⁶

Department of Biomedical Ethics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan |

¹⁰⁷

Department of Infectious Diseases, Rakuwakai Otowa Hospital, Kyoto, Japan |

¹⁰⁸

Department of Health Informatics, School of Public Health, Kyoto University, Kyoto, Japan |

¹⁰⁹

Tohoku University Hospital Emergency Center, Sendai, Japan |

¹¹⁰

Department of Anesthesiology, National Hospital Organization Iwakuni Clinical Center, Iwakuni, Japan |

¹¹¹

Advanced Medical Emergency Department and Critical Care Center, Japan Red Cross Maebashi Hospital, Maebashi, Japan |

¹¹²

Department of Anesthesiology, Kansai Medical University, Hirakata, Japan |

¹¹³

Advanced Emergency and Critical Care Center, Saitama Red Cross Hospital, Saitama, Japan |

¹¹⁴

Department of Emergency and Critical Care Medicine, University of Tsukuba, Tsukuba, Japan |

¹¹⁵

Department of Emergency and Critical Medicine, Showa University Fujigaoka Hospital, Yokohama, Japan |

¹¹⁶

Department of Clinical Epidemiology and Health Economics, School of Public Health, the University of Tokyo, Tokyo, Japan |

¹¹⁷

Shimane Advanced Trauma Center, Izumo, Japan |

¹¹⁸

Department of Primary care and Emergency medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan |

¹¹⁹

Department of Anesthesiology, Kyorin University School of Medicine, Tokyo, Japan |

¹²⁰

Department of ER, Hashimoto Municipal Hospital, Hashimoto, Japan |

¹²¹

Department of Community Medical Supports, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan |

¹²²

Tochigi prefectural Emergency and Critical Care Center, Imperial Gift Foundation Saiseikai, Utsunomiya Hospital, Utsunomiya, Japan |

¹²³

Department of Anesthesiology, Faculty of Medicine, Yamagata University, Yamagata, Japan |

¹²⁴

Department of Internal Medicine, Dialysis Center, Kichijoji Asahi Hospital, Tokyo, Japan |

¹²⁵

Anesthesiology, Emergency Medicine, and Intensive Care Division, Inazawa Municipal Hospital, Inazawa, Japan |

¹²⁶

Department of Anesthesiology and Intensive Care Medicine, Nagoya-City University Graduate School of Medical Sciences, Nagoya, Japan |

¹²⁷

Department of Anesthesiology, Sendai Medical Center, Sendai, Japan |

¹²⁸

Emergency and Critical Care Center, Mie University hospital, Tsu, Japan |

¹²⁹

Department of Emergency Medicine, Fukui Prefectural Hospital, Fukui, Japan |

¹³⁰

Department of Gastroenterological Surgery, Onga Hospital, Fukuoka, Japan |

¹³¹

Department of Emergency and Critical Care Medicine, Seirei Mikatahara General Hospital, Hamamatsu, Japan |

¹³²

Department of Pediatrics, University of Tsukuba Hospital, Tsukuba, Japan |

¹³³

Center for Translational Injury Research, University of Texas Health Science Center at Houston, Houston, USA |

¹³⁴

Department of General Medicine Shintakeo Hospital, Takeo, Japan |

¹³⁵

Department of Emergency and Critical Care Medicine, University of Tsukuba Hospital, Tsukuba, Japan |

¹³⁶

Department of Orthopaedic Surgery, Center for Advanced Joint Function and Reconstructive Spine Surgery, Graduate school of Medicine, Chiba University, Chiba, Japan |

¹³⁷

Department of Pediatric Cardiology and Intensive Care, Gunma Children’s Medical Center, Shibukawa, Japan |

¹³⁸

Department of Emergency and Critical Care Medicine, Tokyo Women’s Medical University Medical Center East, Tokyo, Japan |

¹³⁹

Department of Anesthesiology, Yokohama City University, Yokohama, Japan |

¹⁴⁰

Department of Acute Medicine, Division of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan |

¹⁴¹

Department of Intensive Care, Okayama University Hospital, Okayama, Japan |

¹⁴²

Department of Anesthesiology, Keio University School of Medicine, Tokyo, Japan |

¹⁴³

Department of Intensive Care Medicine, Miyagi Children’s Hospital, Sendai, Japan |

¹⁴⁴

Department of Emergency Medicine, Asahikawa Medical University, Asahikawa, Japan |

¹⁴⁵

Department of Cardiology, Fukuyama City Hospital, Fukuyama, Japan |

¹⁴⁶

Department of General Internal Medicine, Koga General Hospital, Koga, Japan |

¹⁴⁷

Department of Anesthesiology, Osaka Women’s and Children’s Hospital, Izumi, Japan |

¹⁴⁸

Fukuoka Prefectural Psychiatric Center, Dazaifu Hospital, Dazaifu, Japan |

¹⁴⁹

Department of Emergency Medicine, Teikyo University School of Medicine, Tokyo, Japan |

¹⁵⁰

Emergency and critical care center, Kyushu University Hospital, Fukuoka, Japan |

¹⁵¹

Department of Intensive Care Medicine, Kumamoto University Hospital, Kumamoto, Japan |

¹⁵²

Department of Anesthesiology and Intensive Care Unit, Todachuo General Hospital, Toda, Japan |

¹⁵³

Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan |

¹⁵⁴

Department of Emergency and Critical Care Medicine, Saiseikai Yokohamashi Tobu Hospital, Yokohama, Japan |

¹⁵⁵

Department of Emergency, Critical Care, and Disaster Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan |

¹⁵⁶

Intensive Care Unit, Yokohama City Minato Red Cross Hospital, Yokohama, Japan |

¹⁵⁷

Department of Respiratory Medicine, Tokyo Yamate Medical Center, Tokyo, Japan |

¹⁵⁸

Department of Emergency and Critical Care Medicine, Japanese Red Cross Kyoto Daini Hospital, Kyoto, Japan |

¹⁵⁹

Department of Anesthesiology and Critical Care Medicine, Nagoya Daini Red Cross Hospital, Nagoya, Japan |

¹⁶⁰

Department of Emergency Medicine and Intensive Care Medicine, Shizuoka General Hospital, Shizuoka, Japan |

¹⁶¹

Department of Preventive Services, Kyoto University Graduate School of Medicine, Kyoto, Japan |

¹⁶²

Division of Emergency and Critical Care Medicine Niigata University Graduate School of Medical and Dental Science, Niigata, Japan |

¹⁶³

Department of Emergency and Critical Care Medicine, Juntendo University Nerima Hospital, Tokyo, Japan |

¹⁶⁴

Department of Pediatric Critical Care Medicine, Osaka City General Hospital, Osaka, Japan |

¹⁶⁵

Department of Emergency and Critical Care Medicine, Saiseikai Utsunomiya Hospital, Utsunomiya, Japan |

¹⁶⁶

Research Associate of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan |

¹⁶⁷

Department of Emergency Medicine, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Japan |

¹⁶⁸

Department of Emergency Medicine, Saitama Saiseikai Kurihashi Hospital, Kuki, Japan |

¹⁶⁹

Division of Intensive Care Unit, Sakakibara Heart Institute, Tokyo, Japan |

¹⁷⁰

Department of Emergency Medicine and Critical Care Medicine, Tochigi Prefectural Emergency and Critical Care Center, Imperial Foundation Saiseikai Utsunomiya Hospital, Utsunomiya, Japan |

¹⁷¹

Department of Anesthesiology, St. Mary’s Hospital, Our Lady of the Snow Social Medical Corporation, Kurume, Japan |

¹⁷²

Department of Emergency and Critical Care Medicine, Japanese Red Cross Kyoto Daiichi Hospital, Kyoto, Japan |

¹⁷³

Department of Critical Care Medicine, Kyushu University Hospital, Fukuoka, Japan |

¹⁷⁴

Department of Healthcare Epidemiology, School of Public Health in the Graduate School of Medicine, Kyoto University, Kyoto, Japan |

¹⁷⁵

Department of Intensive Care, Chiba Emergency Medical Center, Chiba, Japan |

¹⁷⁶

Department of Internal Medicine, Kanazawa Municipal Hospital, Kanazawa, Japan |

¹⁷⁷

Ishikawa Prefectual Central Hospital Emergency and Critical Care Center, Kanazawa, Japan |

¹⁷⁸

Department of Emergency and General Internal Medicine, Saiseikai Kawaguchi General Hospital, Kawaguchi, Japan |

¹⁷⁹

Department of Emergency and Disaster Medicine, Showa University, Tokyo, Japan |

¹⁸⁰

Department of Cardiology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan |

¹⁸¹

Department of Emergency Medicine, Kobe City Medical Center General Hospital, Kobe, Japan |

¹⁸²

Department of Critical Care and Emergency Medicine, Miyazaki Prefectural Nobeoka Hospital, Nobeoka, Japan |

¹⁸³

Department of Traumatology and Critical Care Medicine, National Defense Medical College, Tokorozawa, Japan |

¹⁸⁴

Department of Emergency Medicine, University of Fukui Hospital, Fukui, Japan |

¹⁸⁵

Pharmaceutical Department, JA Hiroshima General Hospital, Hatsukaichi, Japan |

Publication type: Journal Article

Publication date: 2021-08-25

Springer Nature

Journal of Intensive Care

scimago Q1

wos Q1

SJR: 1.286

CiteScore: 8.2

Impact factor: 4.7

ISSN: 20520492

DOI: 10.1186/s40560-021-00555-7

Copy DOI

PubMed ID: 34433491

Critical Care and Intensive Care Medicine

Abstract

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created as revised from J-SSCG 2016 jointly by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine, was first released in September 2020 and published in February 2021. An English-language version of these guidelines was created based on the contents of the original Japanese-language version. The purpose of this guideline is to assist medical staff in making appropriate decisions to improve the prognosis of patients undergoing treatment for sepsis and septic shock. We aimed to provide high-quality guidelines that are easy to use and understand for specialists, general clinicians, and multidisciplinary medical professionals. J-SSCG 2016 took up new subjects that were not present in SSCG 2016 (e.g., ICU-acquired weakness [ICU-AW], post-intensive care syndrome [PICS], and body temperature management). The J-SSCG 2020 covered a total of 22 areas with four additional new areas (patient- and family-centered care, sepsis treatment system, neuro-intensive treatment, and stress ulcers). A total of 118 important clinical issues (clinical questions, CQs) were extracted regardless of the presence or absence of evidence. These CQs also include those that have been given particular focus within Japan. This is a large-scale guideline covering multiple fields; thus, in addition to the 25 committee members, we had the participation and support of a total of 226 members who are professionals (physicians, nurses, physiotherapists, clinical engineers, and pharmacists) and medical workers with a history of sepsis or critical illness. The GRADE method was adopted for making recommendations, and the modified Delphi method was used to determine recommendations by voting from all committee members. As a result, 79 GRADE-based recommendations, 5 Good Practice Statements (GPS), 18 expert consensuses, 27 answers to background questions (BQs), and summaries of definitions and diagnosis of sepsis were created as responses to 118 CQs. We also incorporated visual information for each CQ according to the time course of treatment, and we will also distribute this as an app. The J-SSCG 2020 is expected to be widely used as a useful bedside guideline in the field of sepsis treatment both in Japan and overseas involving multiple disciplines.

Found

3 citations

Koami Hiroyuki

46 publications, 794 citations, 169 reviews

h-index: 12

Top-30

Journals

	2 4 6 8 10 12 14 16
Journal of Intensive Care	Journal of Intensive Care, 15, 9.93% Journal of Intensive Care 15 publications, 9.93%
Critical Care Medicine	Critical Care Medicine, 8, 5.3% Critical Care Medicine 8 publications, 5.3%
Journal of Infection and Chemotherapy	Journal of Infection and Chemotherapy, 5, 3.31% Journal of Infection and Chemotherapy 5 publications, 3.31%
Acute Medicine & Surgery	Acute Medicine & Surgery, 5, 3.31% Acute Medicine & Surgery 5 publications, 3.31%
Journal of Clinical Medicine	Journal of Clinical Medicine, 4, 2.65% Journal of Clinical Medicine 4 publications, 2.65%
Frontiers in Immunology	Frontiers in Immunology, 4, 2.65% Frontiers in Immunology 4 publications, 2.65%
Cureus	Cureus, 4, 2.65% Cureus 4 publications, 2.65%
Critical Care	Critical Care, 4, 2.65% Critical Care 4 publications, 2.65%
Open Access Emergency Medicine	Open Access Emergency Medicine, 3, 1.99% Open Access Emergency Medicine 3 publications, 1.99%
Medicine (United States)	Medicine (United States), 3, 1.99% Medicine (United States) 3 publications, 1.99%
Journal of Intensive Care Medicine	Journal of Intensive Care Medicine, 3, 1.99% Journal of Intensive Care Medicine 3 publications, 1.99%
Clinical and Applied Thrombosis/Hemostasis	Clinical and Applied Thrombosis/Hemostasis, 2, 1.32% Clinical and Applied Thrombosis/Hemostasis 2 publications, 1.32%
Frontiers in Medicine	Frontiers in Medicine, 2, 1.32% Frontiers in Medicine 2 publications, 1.32%
Nutrients	Nutrients, 2, 1.32% Nutrients 2 publications, 1.32%
International Journal of Molecular Sciences	International Journal of Molecular Sciences, 2, 1.32% International Journal of Molecular Sciences 2 publications, 1.32%
Healthcare	Healthcare, 2, 1.32% Healthcare 2 publications, 1.32%
Infection	Infection, 2, 1.32% Infection 2 publications, 1.32%
International Journal of Hematology	International Journal of Hematology, 2, 1.32% International Journal of Hematology 2 publications, 1.32%
Scientific Reports	Scientific Reports, 2, 1.32% Scientific Reports 2 publications, 1.32%
Renal Replacement Therapy	Renal Replacement Therapy, 2, 1.32% Renal Replacement Therapy 2 publications, 1.32%
American Journal of Clinical Nutrition	American Journal of Clinical Nutrition, 2, 1.32% American Journal of Clinical Nutrition 2 publications, 1.32%
Journal of Thrombosis and Haemostasis	Journal of Thrombosis and Haemostasis, 2, 1.32% Journal of Thrombosis and Haemostasis 2 publications, 1.32%
Annals of Intensive Care	Annals of Intensive Care, 2, 1.32% Annals of Intensive Care 2 publications, 1.32%
Nihon Kyukyu Igakukai Zasshi Journal of Japanese Association for Acute Medicine	Nihon Kyukyu Igakukai Zasshi Journal of Japanese Association for Acute Medicine, 2, 1.32% Nihon Kyukyu Igakukai Zasshi Journal of Japanese Association for Acute Medicine 2 publications, 1.32%
BMJ Open	BMJ Open, 2, 1.32% BMJ Open 2 publications, 1.32%
Heliyon	Heliyon, 2, 1.32% Heliyon 2 publications, 1.32%
Thrombosis Journal	Thrombosis Journal, 2, 1.32% Thrombosis Journal 2 publications, 1.32%
PLoS ONE	PLoS ONE, 2, 1.32% PLoS ONE 2 publications, 1.32%
Journal of the Japanese Society of Intensive Care Medicine	Journal of the Japanese Society of Intensive Care Medicine, 2, 1.32% Journal of the Japanese Society of Intensive Care Medicine 2 publications, 1.32%
	2 4 6 8 10 12 14 16

Publishers

	5 10 15 20 25 30 35 40 45
Springer Nature	Springer Nature, 45, 29.8% Springer Nature 45 publications, 29.8%
Elsevier	Elsevier, 17, 11.26% Elsevier 17 publications, 11.26%
Wiley	Wiley, 14, 9.27% Wiley 14 publications, 9.27%
Ovid Technologies (Wolters Kluwer Health)	Ovid Technologies (Wolters Kluwer Health), 14, 9.27% Ovid Technologies (Wolters Kluwer Health) 14 publications, 9.27%
MDPI	MDPI, 12, 7.95% MDPI 12 publications, 7.95%
Frontiers Media S.A.	Frontiers Media S.A., 9, 5.96% Frontiers Media S.A. 9 publications, 5.96%
Taylor & Francis	Taylor & Francis, 6, 3.97% Taylor & Francis 6 publications, 3.97%
SAGE	SAGE, 5, 3.31% SAGE 5 publications, 3.31%
Cold Spring Harbor Laboratory	Cold Spring Harbor Laboratory, 4, 2.65% Cold Spring Harbor Laboratory 4 publications, 2.65%
BMJ	BMJ, 2, 1.32% BMJ 2 publications, 1.32%
Public Library of Science (PLoS)	Public Library of Science (PLoS), 2, 1.32% Public Library of Science (PLoS) 2 publications, 1.32%
Japanese Society of Intensive Care Medicine	Japanese Society of Intensive Care Medicine, 2, 1.32% Japanese Society of Intensive Care Medicine 2 publications, 1.32%
The American Association of Immunologists	The American Association of Immunologists, 1, 0.66% The American Association of Immunologists 1 publication, 0.66%
American Thoracic Society	American Thoracic Society, 1, 0.66% American Thoracic Society 1 publication, 0.66%
Spandidos Publications	Spandidos Publications, 1, 0.66% Spandidos Publications 1 publication, 0.66%
American Society for Nutrition	American Society for Nutrition, 1, 0.66% American Society for Nutrition 1 publication, 0.66%
AME Publishing Company	AME Publishing Company, 1, 0.66% AME Publishing Company 1 publication, 0.66%
Japan Epidemiological Association	Japan Epidemiological Association, 1, 0.66% Japan Epidemiological Association 1 publication, 0.66%
American Society for Microbiology	American Society for Microbiology, 1, 0.66% American Society for Microbiology 1 publication, 0.66%
S. Karger AG	S. Karger AG, 1, 0.66% S. Karger AG 1 publication, 0.66%
Institute of Applied Biochemistry	Institute of Applied Biochemistry, 1, 0.66% Institute of Applied Biochemistry 1 publication, 0.66%
Korean Society for Parenteral and Enteral Nutrition/The Korean Society of Surgical Metabolism and Nutrition	Korean Society for Parenteral and Enteral Nutrition/The Korean Society of Surgical Metabolism and Nutrition, 1, 0.66% Korean Society for Parenteral and Enteral Nutrition/The Korean Society of Surgical Metabolism and Nutrition 1 publication, 0.66%
The Japanese Association for Infectious Diseases	The Japanese Association for Infectious Diseases, 1, 0.66% The Japanese Association for Infectious Diseases 1 publication, 0.66%
JMIR Publications	JMIR Publications, 1, 0.66% JMIR Publications 1 publication, 0.66%
Baishideng Publishing Group	Baishideng Publishing Group, 1, 0.66% Baishideng Publishing Group 1 publication, 0.66%
	5 10 15 20 25 30 35 40 45

We do not take into account publications without a DOI.
Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.

PDF

Metrics

151

Cite this

GOST |

Cite this

GOST Copy

Egi M. et al. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020) // Journal of Intensive Care. 2021. Vol. 9. No. 1. 53

GOST all authors (up to 50) Copy

Egi M. et al. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020) // Journal of Intensive Care. 2021. Vol. 9. No. 1. 53

RIS |

Cite this

RIS

BibTex

Cite this

BibTex (up to 50 authors) Copy

@article{2021_Egi,

author = {Moritoki Egi and Hiroshi Ogura and Tomoaki Yatabe and Kazuaki Atagi and Inoue Shigeaki and Toshiaki Iba and Yasuyuki Kakihana and Tatsuya Kawasaki and Shigeki Kushimoto and Yasuhiro Kuroda and Joji Kotani and Nobuaki Shime and Takumi Taniguchi and Ryosuke Tsuruta and Kent Doi and MATSUYUKI DOI and Taka-aki Nakada and Masaki Nakane and Seitaro Fujishima and Naoto Hosokawa and Yoshiki Masuda and Asako Matsushima and Naoyuki Matsuda and Kazuma Yamakawa and Yoshitaka Hara and Masaaki Sakuraya and Shinichiro Ohshimo and Yoshitaka Aoki and Mai Inada and Yutaka Umemura and Yusuke Kawai and Yutaka Kondo and Hiroki Saito and Shunsuke Taito and Chikashi Takeda and Takero Terayama and Hideo Tohira and Hideki HASHIMOTO and Kei Hayashida and Toru Hifumi and Tomoya Hirose and Tatsuma Fukuda and Tomoko Fujii and Shinya Miura and Hideto Yasuda and Toshikazu Abe and Kohkichi Andoh and Yuki Iida and Tadashi ISHIHARA and KENTARO IDE and others},

title = {The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)},

journal = {Journal of Intensive Care},

year = {2021},

volume = {9},

publisher = {Springer Nature},

month = {aug},

url = {https://doi.org/10.1186/s40560-021-00555-7},

number = {1},

pages = {53},

doi = {10.1186/s40560-021-00555-7}

}

Publisher

Springer Nature

Journal

Journal of Intensive Care

scimago Q1

wos Q1

SJR

1.286

CiteScore

8.2

Impact factor

4.7

ISSN

20520492 (Electronic)

Profiles

Hiroyuki Koami