Open Access
Effects of Cnidium monnieri (L.) Cuss. fruit extract on sexual behaviors in male rats
Thuy Duong Dau
1
,
Minh-Ha Le
2
,
Tran Thi Giang Huong Nguyen
1
,
Thi Ngoc Mai Dang
3
,
Thi Nguyet Que Do
4
,
Quynh Trang Tran
1
2
Publication type: Journal Article
Publication date: 2020-11-25
General Environmental Science
General Earth and Planetary Sciences
Abstract
Cnidium monnieri (L.) Cuss. has been used for a long time according to the traditional experiences and documentation in order to treat male sexual disorders. Osthole is one of the main bioactive components in Cnidium monnieri (L.) Cuss. In this study, we aimed to evaluate the effect of Cnidium monnieri (L.) Cuss. fruit extract of which osthole content was 35% (determined by HPLC method) on sexual behaviors in adult male rats. Cnidium monnieri (L.) Cuss. fruit extract was administered orally at the dose of 150 mg/kg b.w and after 30 min, male rats were coupled with receptive adult female rats to evaluate sexual behaviors, including mounting and intromission. Cnidium monnieri (L.) Cuss. fruit extract at the dose of 150 mg/kg b.w increased the percentage of rats that mounted and intromitted; increased the intromission frequency and decreased mounting latency and intromission latency. Cnidium monnieri (L.) Cuss. fruit extract increased the ability to mount and intromit in rats, and scientifically support the traditional use of Cnidium monnieri (L.) Cuss. in treatment of male sexual disorders.
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Dau T. D. et al. Effects of Cnidium monnieri (L.) Cuss. fruit extract on sexual behaviors in male rats // Clinical Phytoscience. 2020. Vol. 6. No. 1. 80
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Dau T. D., Le M., Nguyen T. T. G. H., Dang T. N. M., Do T. N. Q., Tran Q. T. Effects of Cnidium monnieri (L.) Cuss. fruit extract on sexual behaviors in male rats // Clinical Phytoscience. 2020. Vol. 6. No. 1. 80
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TY - JOUR
DO - 10.1186/s40816-020-00227-3
UR - https://doi.org/10.1186/s40816-020-00227-3
TI - Effects of Cnidium monnieri (L.) Cuss. fruit extract on sexual behaviors in male rats
T2 - Clinical Phytoscience
AU - Dau, Thuy Duong
AU - Le, Minh-Ha
AU - Nguyen, Tran Thi Giang Huong
AU - Dang, Thi Ngoc Mai
AU - Do, Thi Nguyet Que
AU - Tran, Quynh Trang
PY - 2020
DA - 2020/11/25
PB - Springer Nature
IS - 1
VL - 6
SN - 2199-1197
ER -
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@article{2020_Dau,
author = {Thuy Duong Dau and Minh-Ha Le and Tran Thi Giang Huong Nguyen and Thi Ngoc Mai Dang and Thi Nguyet Que Do and Quynh Trang Tran},
title = {Effects of Cnidium monnieri (L.) Cuss. fruit extract on sexual behaviors in male rats},
journal = {Clinical Phytoscience},
year = {2020},
volume = {6},
publisher = {Springer Nature},
month = {nov},
url = {https://doi.org/10.1186/s40816-020-00227-3},
number = {1},
pages = {80},
doi = {10.1186/s40816-020-00227-3}
}