Open Access
Neurodegenerative disorders associated with genes of mitochondria
Vaibhav S. Marde
1
,
Prerna L. Tiwari
2
,
Nitu L. Wankhede
3
,
Brijesh G. Taksande
3
,
Aman B. Upaganlawar
4
,
Milind J. Umekar
3
,
Mayur B. Kale
3
2
Springer Nature Technology and Publishing Solutions (SNTPS), Pune, India
|
3
Smt. Kishoritai Bhoyar College of Pharmacy, Nagpur, India
|
4
SNJB’s Shriman Sureshdada Jain College of Pharmacy, Chandwad, India
|
Publication type: Journal Article
Publication date: 2021-03-16
wos Q2
SJR: —
CiteScore: —
Impact factor: 3.0
ISSN: 23147245, 23147253
General Medicine
Abstract
Over the last decade, aggregating evidences suggested that there is a causative link between mutation in gene associated with mitochondrial dysfunction and development of several neurodegenerative disorders. Recent structural and functional studies associated with mitochondrial genes have shown that mitochondrial abnormalities possibly lead to mitochondrial dysfunction. Several studies on animal models of neurodegenerative diseases and mitochondrial genes have provided compelling evidence that mitochondria is involved in the initiation as well as progression of diseases such as Parkinson’s disease (PD), Alzheimer’s disease (AD), Huntington’s disease (HD), and Friedreich ataxia (FA). In this mini-review, we have discussed the different etiologic and pathogenesis connected with the mitochondrial dysfunction and relevant neurodegenerative diseases that underlie the dominant part of mitochondrial genes in the disease development and its progress.
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16
Total citations:
16
Citations from 2024:
10
(62.5%)
Cite this
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BibTex
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GOST
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Marde V. S. et al. Neurodegenerative disorders associated with genes of mitochondria // Future Journal of Pharmaceutical Sciences. 2021. Vol. 7. No. 1. 66
GOST all authors (up to 50)
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Marde V. S., Tiwari P. L., Wankhede N. L., Taksande B. G., Upaganlawar A. B., Umekar M. J., Kale M. B. Neurodegenerative disorders associated with genes of mitochondria // Future Journal of Pharmaceutical Sciences. 2021. Vol. 7. No. 1. 66
Cite this
RIS
Copy
TY - JOUR
DO - 10.1186/s43094-021-00215-5
UR - https://doi.org/10.1186/s43094-021-00215-5
TI - Neurodegenerative disorders associated with genes of mitochondria
T2 - Future Journal of Pharmaceutical Sciences
AU - Marde, Vaibhav S.
AU - Tiwari, Prerna L.
AU - Wankhede, Nitu L.
AU - Taksande, Brijesh G.
AU - Upaganlawar, Aman B.
AU - Umekar, Milind J.
AU - Kale, Mayur B.
PY - 2021
DA - 2021/03/16
PB - Springer Nature
IS - 1
VL - 7
SN - 2314-7245
SN - 2314-7253
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Marde,
author = {Vaibhav S. Marde and Prerna L. Tiwari and Nitu L. Wankhede and Brijesh G. Taksande and Aman B. Upaganlawar and Milind J. Umekar and Mayur B. Kale},
title = {Neurodegenerative disorders associated with genes of mitochondria},
journal = {Future Journal of Pharmaceutical Sciences},
year = {2021},
volume = {7},
publisher = {Springer Nature},
month = {mar},
url = {https://doi.org/10.1186/s43094-021-00215-5},
number = {1},
pages = {66},
doi = {10.1186/s43094-021-00215-5}
}