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volume 74 issue 1 pages 42

TRPV2: a universal regulator in cellular physiology with a yet poorly defined thermosensitivity

Publication typeJournal Article
Publication date2024-09-16
scimago Q2
wos Q2
SJR0.791
CiteScore4.2
Impact factor3.2
ISSN18806546, 18806562
Abstract

Transient receptor potential (TRP) ion channels serve as sensors for variations in ambient temperature, modulating both thermoregulation and temperature responsive cellular processes. Among these, the vanilloid TRP subfamily (TRPV) comprises six members and at least four of these members (TRPV1-TRPV4) have been associated with thermal sensation. TRPV2 has been described as a sensor for noxious heat, but subsequent studies have unveiled a more complex role for TRPV2 beyond temperature perception. This comprehensive review aims to elucidate the intricate thermosensitivity of TRPV2 by synthesizing current knowledge on its biophysical properties, expression pattern and known physiological functions associated with thermosensation.

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GOST |
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GOST Copy
Fricke T. C. et al. TRPV2: a universal regulator in cellular physiology with a yet poorly defined thermosensitivity // Journal of Physiological Sciences. 2024. Vol. 74. No. 1. p. 42.
GOST all authors (up to 50) Copy
Fricke T. C., Leffler A. TRPV2: a universal regulator in cellular physiology with a yet poorly defined thermosensitivity // Journal of Physiological Sciences. 2024. Vol. 74. No. 1. p. 42.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1186/s12576-024-00936-1
UR - https://jps.biomedcentral.com/articles/10.1186/s12576-024-00936-1
TI - TRPV2: a universal regulator in cellular physiology with a yet poorly defined thermosensitivity
T2 - Journal of Physiological Sciences
AU - Fricke, Tabea C.
AU - Leffler, Andreas
PY - 2024
DA - 2024/09/16
PB - Elsevier
SP - 42
IS - 1
VL - 74
PMID - 39285320
SN - 1880-6546
SN - 1880-6562
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2024_Fricke,
author = {Tabea C. Fricke and Andreas Leffler},
title = {TRPV2: a universal regulator in cellular physiology with a yet poorly defined thermosensitivity},
journal = {Journal of Physiological Sciences},
year = {2024},
volume = {74},
publisher = {Elsevier},
month = {sep},
url = {https://jps.biomedcentral.com/articles/10.1186/s12576-024-00936-1},
number = {1},
pages = {42},
doi = {10.1186/s12576-024-00936-1}
}
MLA
Cite this
MLA Copy
Fricke, Tabea C., et al. “TRPV2: a universal regulator in cellular physiology with a yet poorly defined thermosensitivity.” Journal of Physiological Sciences, vol. 74, no. 1, Sep. 2024, p. 42. https://jps.biomedcentral.com/articles/10.1186/s12576-024-00936-1.