Open Access

Journal of Nanobiotechnology

, volume 19 , issue 1 , publication number 41

Thermo-responsive polymer encapsulated gold nanorods for single continuous wave laser-induced photodynamic/photothermal tumour therapy

Beilei Gong ^{1, 2}

Yuanbing Shen ^{1, 2}

Huiyan Li ³

Xiaojun Li ⁴

Huan Xia ⁵

Jihong Zhou ⁶

Yuqing Chen ^{1, 2}

Jian Wu ^{3, 7}

Wei Li ¹

Hide authors affiliations Show authors affiliations: 7 affiliations

Department of Respiratory Disease, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China |

Center for Clinical Medicine of Respiratory Disease (tumor) in Anhui, Bengbu, China |

Department of Medical Microbiology, MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences, Fudan University, Shanghai, China |

⁴

Department of Thoracic Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, China |

⁵

Department of Respiratory Disease, People’s Hospital of Shannan, Shannan, China |

⁶

Anhui Province Key Laboratory of Translational Cancer Research, Bengbu, China |

⁷

Dept. of Gastroenterology & Hepatology, Zhongshan Hospital of Fudan University, Shanghai, China |

Publication type: Journal Article

Publication date: 2021-02-08

Springer Nature

Journal of Nanobiotechnology

scimago Q1

wos Q1

SJR: 2.282

CiteScore: 16.8

Impact factor: 12.6

ISSN: 14773155

DOI: 10.1186/s12951-020-00754-8

Copy DOI

PubMed ID: 33557807

Medicine (miscellaneous)

Pharmaceutical Science

Molecular Medicine

Applied Microbiology and Biotechnology

Bioengineering

Biomedical Engineering

Abstract

Owing to strong and tunable surface plasmon resonance (SPR) effect and good biocompatibility, gold nanoparticles have been suggested to be a versatile platform for a broad range of biomedical applications. In this study, a new nanoplatform of thermo-responsive polymer encapsulated gold nanorods incorporating indocyanine green (ICG) was designed to couple the photothermal properties of gold nanorods (AuNRs) and the photodynamic properties of ICG to enhance the photodynamic/photothermal combination therapy (PDT/PTT). In addition to the significantly increased payload and enhancing photostability of ICG, the polymer shell in the nanoplatform also has thermo-responsive characteristics that can control the release of drugs at tumour sites upon the laser irradiation. On the basis of these improvements, the nanoplatform strongly increased drug aggregation at the tumour site and improved the photothermal/photodynamic therapeutic efficacy. These results suggest that this nanoplatform would be a great potential system for tumour imaging and antitumour therapy.

Found

Top-30

Journals

	1 2 3 4 5
Journal of Nanobiotechnology	Journal of Nanobiotechnology, 5, 7.81% Journal of Nanobiotechnology 5 publications, 7.81%
Pharmaceutics	Pharmaceutics, 3, 4.69% Pharmaceutics 3 publications, 4.69%
Journal of Materials Chemistry B	Journal of Materials Chemistry B, 3, 4.69% Journal of Materials Chemistry B 3 publications, 4.69%
Biomaterials Advances	Biomaterials Advances, 2, 3.13% Biomaterials Advances 2 publications, 3.13%
Nanoscale	Nanoscale, 2, 3.13% Nanoscale 2 publications, 3.13%
Advanced Therapeutics	Advanced Therapeutics, 2, 3.13% Advanced Therapeutics 2 publications, 3.13%
International Journal of Pharmaceutics	International Journal of Pharmaceutics, 2, 3.13% International Journal of Pharmaceutics 2 publications, 3.13%
Nanomaterials	Nanomaterials, 1, 1.56% Nanomaterials 1 publication, 1.56%
Cancers	Cancers, 1, 1.56% Cancers 1 publication, 1.56%
Photodiagnosis and Photodynamic Therapy	Photodiagnosis and Photodynamic Therapy, 1, 1.56% Photodiagnosis and Photodynamic Therapy 1 publication, 1.56%
Materials Today Chemistry	Materials Today Chemistry, 1, 1.56% Materials Today Chemistry 1 publication, 1.56%
Carbohydrate Polymers	Carbohydrate Polymers, 1, 1.56% Carbohydrate Polymers 1 publication, 1.56%
Life Sciences	Life Sciences, 1, 1.56% Life Sciences 1 publication, 1.56%
Bioactive Materials	Bioactive Materials, 1, 1.56% Bioactive Materials 1 publication, 1.56%
Smart Materials in Medicine	Smart Materials in Medicine, 1, 1.56% Smart Materials in Medicine 1 publication, 1.56%
Materials Research Express	Materials Research Express, 1, 1.56% Materials Research Express 1 publication, 1.56%
Small Structures	Small Structures, 1, 1.56% Small Structures 1 publication, 1.56%
ACS Nano	ACS Nano, 1, 1.56% ACS Nano 1 publication, 1.56%
Separation and Purification Technology	Separation and Purification Technology, 1, 1.56% Separation and Purification Technology 1 publication, 1.56%
Lasers in Medical Science	Lasers in Medical Science, 1, 1.56% Lasers in Medical Science 1 publication, 1.56%
Chemistry and Biodiversity	Chemistry and Biodiversity, 1, 1.56% Chemistry and Biodiversity 1 publication, 1.56%
RSC Advances	RSC Advances, 1, 1.56% RSC Advances 1 publication, 1.56%
ACS Applied Nano Materials	ACS Applied Nano Materials, 1, 1.56% ACS Applied Nano Materials 1 publication, 1.56%
Biomaterials Research	Biomaterials Research, 1, 1.56% Biomaterials Research 1 publication, 1.56%
Current Pharmaceutical Design	Current Pharmaceutical Design, 1, 1.56% Current Pharmaceutical Design 1 publication, 1.56%
Anti-Cancer Agents in Medicinal Chemistry	Anti-Cancer Agents in Medicinal Chemistry, 1, 1.56% Anti-Cancer Agents in Medicinal Chemistry 1 publication, 1.56%
ACS applied materials & interfaces	ACS applied materials & interfaces, 1, 1.56% ACS applied materials & interfaces 1 publication, 1.56%
Advances in Heat Transfer	Advances in Heat Transfer, 1, 1.56% Advances in Heat Transfer 1 publication, 1.56%
Chemical & Biomedical Imaging	Chemical & Biomedical Imaging, 1, 1.56% Chemical & Biomedical Imaging 1 publication, 1.56%
	1 2 3 4 5

Publishers

	5 10 15 20 25
Elsevier	Elsevier, 23, 35.94% Elsevier 23 publications, 35.94%
Wiley	Wiley, 9, 14.06% Wiley 9 publications, 14.06%
Springer Nature	Springer Nature, 7, 10.94% Springer Nature 7 publications, 10.94%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 7, 10.94% Royal Society of Chemistry (RSC) 7 publications, 10.94%
MDPI	MDPI, 6, 9.38% MDPI 6 publications, 9.38%
American Chemical Society (ACS)	American Chemical Society (ACS), 4, 6.25% American Chemical Society (ACS) 4 publications, 6.25%
Bentham Science Publishers Ltd.	Bentham Science Publishers Ltd., 2, 3.13% Bentham Science Publishers Ltd. 2 publications, 3.13%
IOP Publishing	IOP Publishing, 1, 1.56% IOP Publishing 1 publication, 1.56%
American Association for the Advancement of Science (AAAS)	American Association for the Advancement of Science (AAAS), 1, 1.56% American Association for the Advancement of Science (AAAS) 1 publication, 1.56%
The Russian Academy of Sciences	The Russian Academy of Sciences, 1, 1.56% The Russian Academy of Sciences 1 publication, 1.56%
Pleiades Publishing	Pleiades Publishing, 1, 1.56% Pleiades Publishing 1 publication, 1.56%
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii	Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii, 1, 1.56% Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii 1 publication, 1.56%
	5 10 15 20 25

We do not take into account publications without a DOI.
Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.

PDF

Metrics

Cite this

GOST |

Cite this

GOST Copy

Gong B. et al. Thermo-responsive polymer encapsulated gold nanorods for single continuous wave laser-induced photodynamic/photothermal tumour therapy // Journal of Nanobiotechnology. 2021. Vol. 19. No. 1. 41

GOST all authors (up to 50) Copy

Gong B., Shen Y., Li H., Li X., Xia H., Zhou J., Chen Y., Wu J., Li W. Thermo-responsive polymer encapsulated gold nanorods for single continuous wave laser-induced photodynamic/photothermal tumour therapy // Journal of Nanobiotechnology. 2021. Vol. 19. No. 1. 41

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1186/s12951-020-00754-8

UR - https://doi.org/10.1186/s12951-020-00754-8

TI - Thermo-responsive polymer encapsulated gold nanorods for single continuous wave laser-induced photodynamic/photothermal tumour therapy

T2 - Journal of Nanobiotechnology

AU - Gong, Beilei

AU - Shen, Yuanbing

AU - Li, Huiyan

AU - Li, Xiaojun

AU - Xia, Huan

AU - Zhou, Jihong

AU - Chen, Yuqing

AU - Wu, Jian

AU - Li, Wei

PY - 2021

DA - 2021/02/08

PB - Springer Nature

IS - 1

VL - 19

PMID - 33557807

SN - 1477-3155

ER -

BibTex

Cite this

BibTex (up to 50 authors) Copy

@article{2021_Gong,

author = {Beilei Gong and Yuanbing Shen and Huiyan Li and Xiaojun Li and Huan Xia and Jihong Zhou and Yuqing Chen and Jian Wu and Wei Li},

title = {Thermo-responsive polymer encapsulated gold nanorods for single continuous wave laser-induced photodynamic/photothermal tumour therapy},

journal = {Journal of Nanobiotechnology},

year = {2021},

volume = {19},

publisher = {Springer Nature},

month = {feb},

url = {https://doi.org/10.1186/s12951-020-00754-8},

number = {1},

pages = {41},

doi = {10.1186/s12951-020-00754-8}

}

Publisher

Springer Nature

Journal

Journal of Nanobiotechnology

scimago Q1

wos Q1

SJR

2.282

CiteScore

16.8

Impact factor

12.6

ISSN

14773155 (Print, Electronic)