том 51 издание 7 страницы 853-855

Muscle Relaxant Activity of Methocarbamol Enantiomers in Mice

Тип публикацииJournal Article
Дата публикации1999-07-01
SCImago Q2
WOS Q2
БС1
SJR0.765
CiteScore6.7
Impact factor3.7
ISSN00223573, 20427158, 23282150
Pharmacology
Pharmaceutical Science
Краткое описание

Documented studies support the emerging idea that drug enantiomers could have different pharmacological activity. Our bibliographical data have shown that so far no report has been published on the pharmacological activity of individual enantiomers of methocarbamol.

This study was conducted to characterize the muscle relaxant activity of methocarbamol enantiomers. The rotarod test was used to compare the muscle relaxant activity of racemic methocarbamol and pure enantiomers after intraperitoneal administration of the enantiomers to mice.

The results show that (+)- R-methocarbamol has higher muscle relaxant activity compared with racemic methocarbamol or (-)- S-methocarbamol.

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ГОСТ |
Цитировать
Souri E. et al. Muscle Relaxant Activity of Methocarbamol Enantiomers in Mice // Journal of Pharmacy and Pharmacology. 1999. Vol. 51. No. 7. pp. 853-855.
ГОСТ со всеми авторами (до 50) Скопировать
Souri E., Sharifzadeh M., Farsam H., Gharavi N. Muscle Relaxant Activity of Methocarbamol Enantiomers in Mice // Journal of Pharmacy and Pharmacology. 1999. Vol. 51. No. 7. pp. 853-855.
RIS |
Цитировать
TY - JOUR
DO - 10.1211/0022357991773069
UR - https://doi.org/10.1211/0022357991773069
TI - Muscle Relaxant Activity of Methocarbamol Enantiomers in Mice
T2 - Journal of Pharmacy and Pharmacology
AU - Souri, E
AU - Sharifzadeh, M.
AU - Farsam, H.
AU - Gharavi, N.
PY - 1999
DA - 1999/07/01
PB - Wiley
SP - 853-855
IS - 7
VL - 51
PMID - 10467962
SN - 0022-3573
SN - 2042-7158
SN - 2328-2150
ER -
BibTex |
Цитировать
BibTex (до 50 авторов) Скопировать
@article{1999_Souri,
author = {E Souri and M. Sharifzadeh and H. Farsam and N. Gharavi},
title = {Muscle Relaxant Activity of Methocarbamol Enantiomers in Mice},
journal = {Journal of Pharmacy and Pharmacology},
year = {1999},
volume = {51},
publisher = {Wiley},
month = {jul},
url = {https://doi.org/10.1211/0022357991773069},
number = {7},
pages = {853--855},
doi = {10.1211/0022357991773069}
}
MLA
Цитировать
Souri, E., et al. “Muscle Relaxant Activity of Methocarbamol Enantiomers in Mice.” Journal of Pharmacy and Pharmacology, vol. 51, no. 7, Jul. 1999, pp. 853-855. https://doi.org/10.1211/0022357991773069.
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