Chemistry Letters, volume 20, issue 5, pages 745-748

The Benzimidazole Dye Hoechst 8208 Intercalates into DNA

YUKIO KUBOTA
, 
Hiroyuki Nakamura
Publication type: Journal Article
Publication date: 1991-05-01
scimago Q2
SJR: 0.423
CiteScore: 3.0
Impact factor: 1.4
ISSN: 03667022, 13480715
General Chemistry
Abstract
The interaction of the benzimidazole dye Hoechst 8208 (H8208) with DNA has been studied by optical, hydrodynamic, and 1H NMR techniques. All of the results clearly indicate that H8208 intercalates between successive DNA base pairs.
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