volume 39 issue 4 pages 1085-1087

Synthesis of axially dissymmetric biphenylbisphosphine ligands, bimops and asymmetric hydrogenations of .BETA.-keto ester and .ALPHA.,.BETA.-unsaturated carboxylic acid catalyzed by their ruthenium (II) complexes.

Naoko Yamamoto
Masanao Murata
Toshiaki Morimoto
Kazuo ACHIWA
Publication typeJournal Article
Publication date2011-12-08
scimago Q3
wos Q3
SJR0.349
CiteScore2.7
Impact factor1.3
ISSN00092363, 13475223
General Chemistry
Drug Discovery
General Medicine
Abstract
Axially dissymmetric biphenylbisphosphine ligands, BIMOP (1a) and p-MeO-BIMOP (1b) have been newly designed and prepared. The ruthenium (II) complexes of (R)-1a and 1b proved to be excellent catalysts in asymmetric hydrogenations of methyl 3-oxobutanoate and tiglic acid affording (R)-methyl 3-hydroxybutanoate of 95-99 % ee and (R)-2-methylbutyric acid of 86-91 % ee, respectively.
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Yamamoto N. et al. Synthesis of axially dissymmetric biphenylbisphosphine ligands, bimops and asymmetric hydrogenations of .BETA.-keto ester and .ALPHA.,.BETA.-unsaturated carboxylic acid catalyzed by their ruthenium (II) complexes. // Chemical and Pharmaceutical Bulletin. 2011. Vol. 39. No. 4. pp. 1085-1087.
GOST all authors (up to 50) Copy
Yamamoto N., Murata M., Morimoto T., ACHIWA K. Synthesis of axially dissymmetric biphenylbisphosphine ligands, bimops and asymmetric hydrogenations of .BETA.-keto ester and .ALPHA.,.BETA.-unsaturated carboxylic acid catalyzed by their ruthenium (II) complexes. // Chemical and Pharmaceutical Bulletin. 2011. Vol. 39. No. 4. pp. 1085-1087.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1248/cpb.39.1085
UR - https://doi.org/10.1248/cpb.39.1085
TI - Synthesis of axially dissymmetric biphenylbisphosphine ligands, bimops and asymmetric hydrogenations of .BETA.-keto ester and .ALPHA.,.BETA.-unsaturated carboxylic acid catalyzed by their ruthenium (II) complexes.
T2 - Chemical and Pharmaceutical Bulletin
AU - Yamamoto, Naoko
AU - Murata, Masanao
AU - Morimoto, Toshiaki
AU - ACHIWA, Kazuo
PY - 2011
DA - 2011/12/08
PB - Pharmaceutical Society of Japan
SP - 1085-1087
IS - 4
VL - 39
SN - 0009-2363
SN - 1347-5223
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2011_Yamamoto,
author = {Naoko Yamamoto and Masanao Murata and Toshiaki Morimoto and Kazuo ACHIWA},
title = {Synthesis of axially dissymmetric biphenylbisphosphine ligands, bimops and asymmetric hydrogenations of .BETA.-keto ester and .ALPHA.,.BETA.-unsaturated carboxylic acid catalyzed by their ruthenium (II) complexes.},
journal = {Chemical and Pharmaceutical Bulletin},
year = {2011},
volume = {39},
publisher = {Pharmaceutical Society of Japan},
month = {dec},
url = {https://doi.org/10.1248/cpb.39.1085},
number = {4},
pages = {1085--1087},
doi = {10.1248/cpb.39.1085}
}
MLA
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MLA Copy
Yamamoto, Naoko, et al. “Synthesis of axially dissymmetric biphenylbisphosphine ligands, bimops and asymmetric hydrogenations of .BETA.-keto ester and .ALPHA.,.BETA.-unsaturated carboxylic acid catalyzed by their ruthenium (II) complexes..” Chemical and Pharmaceutical Bulletin, vol. 39, no. 4, Dec. 2011, pp. 1085-1087. https://doi.org/10.1248/cpb.39.1085.