Synthesis of 4′-C-Ethynyl-β-D-arabino- and 4′-C-Ethynyl-2′-deoxy-β-D-ribo- pentofuranosyl Pyrimidines, and Their Biological Evaluation
Тип публикации: Journal Article
Дата публикации: 1999-01-01
scimago Q3
wos Q3
БС3
SJR: 0.405
CiteScore: 3.1
Impact factor: 1.3
ISSN: 09168451, 13476947
PubMed ID:
10427708
Organic Chemistry
Biochemistry
Molecular Biology
General Medicine
Analytical Chemistry
Applied Microbiology and Biotechnology
Biotechnology
Краткое описание
4'-C-Ethynyl-beta-D-arabino-pentofuranosyl thymine (14) and cytosine (16), and 4'-C-ethynyl-2'-deoxy-beta-D-ribo-pentofuranosyl thymine (25) and cytosine (27) were synthesized by properly protected 4'-C-hydroxy-methyl-3,5-di-O-benzyl-alpha-D-ribo-pentofuranose (1) from D-glucose. Among them, 2'-deoxy derivatives 25 and 27 exhibited antiviral activity, while cytidine derivatives 16 and 27 inhibited the growth of neoplastic cells.
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ГОСТ
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Kohgo S., Horie H., Ohrui H. Synthesis of 4′-C-Ethynyl-β-D-arabino- and 4′-C-Ethynyl-2′-deoxy-β-D-ribo- pentofuranosyl Pyrimidines, and Their Biological Evaluation // Bioscience, Biotechnology and Biochemistry. 1999. Vol. 63. No. 6. pp. 1146-1149.
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Kohgo S., Horie H., Ohrui H. Synthesis of 4′-C-Ethynyl-β-D-arabino- and 4′-C-Ethynyl-2′-deoxy-β-D-ribo- pentofuranosyl Pyrimidines, and Their Biological Evaluation // Bioscience, Biotechnology and Biochemistry. 1999. Vol. 63. No. 6. pp. 1146-1149.
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TY - JOUR
DO - 10.1271/bbb.63.1146
UR - https://doi.org/10.1271/bbb.63.1146
TI - Synthesis of 4′-C-Ethynyl-β-D-arabino- and 4′-C-Ethynyl-2′-deoxy-β-D-ribo- pentofuranosyl Pyrimidines, and Their Biological Evaluation
T2 - Bioscience, Biotechnology and Biochemistry
AU - Kohgo, Satoru
AU - Horie, Hiroko
AU - Ohrui, Hiroshi
PY - 1999
DA - 1999/01/01
PB - Taylor & Francis
SP - 1146-1149
IS - 6
VL - 63
PMID - 10427708
SN - 0916-8451
SN - 1347-6947
ER -
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BibTex (до 50 авторов)
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@article{1999_Kohgo,
author = {Satoru Kohgo and Hiroko Horie and Hiroshi Ohrui},
title = {Synthesis of 4′-C-Ethynyl-β-D-arabino- and 4′-C-Ethynyl-2′-deoxy-β-D-ribo- pentofuranosyl Pyrimidines, and Their Biological Evaluation},
journal = {Bioscience, Biotechnology and Biochemistry},
year = {1999},
volume = {63},
publisher = {Taylor & Francis},
month = {jan},
url = {https://doi.org/10.1271/bbb.63.1146},
number = {6},
pages = {1146--1149},
doi = {10.1271/bbb.63.1146}
}
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MLA
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Kohgo, Satoru, et al. “Synthesis of 4′-C-Ethynyl-β-D-arabino- and 4′-C-Ethynyl-2′-deoxy-β-D-ribo- pentofuranosyl Pyrimidines, and Their Biological Evaluation.” Bioscience, Biotechnology and Biochemistry, vol. 63, no. 6, Jan. 1999, pp. 1146-1149. https://doi.org/10.1271/bbb.63.1146.