World Journal of Clinical Cases, volume 13, issue 8

Unusual ovarian hyperstimulation syndrome presentation: Pleural effusion without ascites. A case report

Íngrid Solsona
Sara Peralta
Yasmina Barral
Francisco Fàbregues
Pepita Giménez-Bonafé
Publication typeJournal Article
Publication date2025-03-16
wos Q3
SJR
CiteScore
Impact factor1
ISSN23078960
Abstract

BACKGROUND

Ovarian hyperstimulation syndrome (OHSS) is a life-threatening complication that can occur in the luteal phase or early pregnancy after controlled ovarian stimulation. This case report highlights a unique manifestation of OHSS involving pleural effusion (PE) in a patient without identifiable risk factors.

CASE SUMMARY

A 39-year-old woman who underwent controlled ovarian hyperstimulation for an in vitro fertilization (IVF) cycle experienced dyspnea on the eleventh day of post oocyte retrieval. The diagnosis was severe OHSS with a unique manifestation of PE without ascites. Clinical management involved fluid balance and treatment with albumin, furosemide, thromboembolic prophylaxis, and thoracentesis. A continued drainage of the pleural cavity was performed. The patient had a favorable outcome, and a dichorionic diamniotic gestation passed without incident.

CONCLUSION

OHSS and its potential complications can include respiratory distress and PE, as well as thromboembolic disorders.

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