Formation of Dimers Composed of a Single Short dsDNA Connecting Two Gold Nanoparticles

Dachlika H., Stern A., Rotem D., Porath D.
Publication typeJournal Article
Publication date2023-03-18
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ISSN22454551, 22458824
Abstract

We report synthesis of dimers composed of a single short double-stranded(ds)DNA molecule connecting two gold nanoparticles (GNPs). Such struc-tures may be useful for electrical transport measurements through dsDNAmolecules and for other research purposes. When the DNA molecules areshort with respect to the size of the GNP, gel electrophoresis cannot separ-ate GNPs with different numbers of DNA molecules attached to them. Wepresent two methods to separate GNPs connected to single short thiolatedsingle-stranded (ss)DNA. The separation is performed by hybridizing theDNA/GNP conjugates with long, partially complementary, ssDNA or withcomplementary ssDNA connected to GNPs of smaller size. The separatedGNPs with a single short ssDNA were used to form dimers consisting ofGNPs connected by a single short dsDNA molecule.

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Dachlika H. et al. Formation of Dimers Composed of a Single Short dsDNA Connecting Two Gold Nanoparticles // Journal of Self-Assembly and Molecular Electronics (SAME). 2023.
GOST all authors (up to 50) Copy
Dachlika H., Stern A., Rotem D., Porath D. Formation of Dimers Composed of a Single Short dsDNA Connecting Two Gold Nanoparticles // Journal of Self-Assembly and Molecular Electronics (SAME). 2023.
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TY - JOUR
DO - 10.13052/same2245-4551.114
UR - https://doi.org/10.13052/same2245-4551.114
TI - Formation of Dimers Composed of a Single Short dsDNA Connecting Two Gold Nanoparticles
T2 - Journal of Self-Assembly and Molecular Electronics (SAME)
AU - Dachlika, H
AU - Stern, A
AU - Rotem, D
AU - Porath, D
PY - 2023
DA - 2023/03/18
PB - River Publishers
SN - 2245-4551
SN - 2245-8824
ER -
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@article{2023_Dachlika,
author = {H Dachlika and A Stern and D Rotem and D Porath},
title = {Formation of Dimers Composed of a Single Short dsDNA Connecting Two Gold Nanoparticles},
journal = {Journal of Self-Assembly and Molecular Electronics (SAME)},
year = {2023},
publisher = {River Publishers},
month = {mar},
url = {https://doi.org/10.13052/same2245-4551.114},
doi = {10.13052/same2245-4551.114}
}