Open Access
Optical coherence microangiography of the mouse kidney for diagnosis of circulatory disorders
Ekaterina S. Prikhozhdenko
2, 3
,
Oksana A. Mayorova
2, 3
,
Valentina O. Plastun
2, 3
,
Olga I Gusliakova
2, 3
,
Natalia A. Shushunova
2, 3
,
Oleg A Kulikov
4
,
Valery V. Tuchin
2, 3, 5, 6
,
Gleb B. Sukhorukov
1, 7
,
Olga Sindeeva
1, 2, 3
1
Skolkovo Innovation Center
|
6
Laboratory of Laser Diagnostics of Technical and Living Systems
Тип публикации: Journal Article
Дата публикации: 2021-06-28
scimago Q1
wos Q1
БС1
SJR: 0.896
CiteScore: 6.4
Impact factor: 3.2
ISSN: 21567085
PubMed ID:
34457426
Biotechnology
Atomic and Molecular Physics, and Optics
Краткое описание
Optical coherence tomography (OCT) has become widespread in clinical applications in which precise three-dimensional functional imaging of living organs is required. Nevertheless, the kidney is inaccessible for the high resolution OCT imaging due to a high light attenuation coefficient of skin and soft tissues that significantly limits the penetration depth of the probing laser beam. Here, we introduce a surgical protocol and fixation scheme that enables functional visualization of kidney’s peritubular capillaries via OCT microangiography. The model of reversible/irreversible glomerulus embolization using drug microcarriers confirms the ability of OCT to detect circulatory disorders. This approach can be used for choosing optimal carriers, their dosages and diagnosis of other blood flow pathologies.
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ГОСТ
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Abdurashitov A. S. et al. Optical coherence microangiography of the mouse kidney for diagnosis of circulatory disorders // Biomedical Optics Express. 2021. Vol. 12. No. 7. p. 4467.
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Abdurashitov A. S., Prikhozhdenko E. S., Mayorova O. A., Plastun V. O., Gusliakova O. I., Shushunova N. A., Kulikov O. A., Tuchin V. V., Sukhorukov G. B., Sindeeva O. Optical coherence microangiography of the mouse kidney for diagnosis of circulatory disorders // Biomedical Optics Express. 2021. Vol. 12. No. 7. p. 4467.
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TY - JOUR
DO - 10.1364/BOE.430393
UR - https://opg.optica.org/abstract.cfm?URI=boe-12-7-4467
TI - Optical coherence microangiography of the mouse kidney for diagnosis of circulatory disorders
T2 - Biomedical Optics Express
AU - Abdurashitov, Arkady S.
AU - Prikhozhdenko, Ekaterina S.
AU - Mayorova, Oksana A.
AU - Plastun, Valentina O.
AU - Gusliakova, Olga I
AU - Shushunova, Natalia A.
AU - Kulikov, Oleg A
AU - Tuchin, Valery V.
AU - Sukhorukov, Gleb B.
AU - Sindeeva, Olga
PY - 2021
DA - 2021/06/28
PB - Optica Publishing Group
SP - 4467
IS - 7
VL - 12
PMID - 34457426
SN - 2156-7085
ER -
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BibTex (до 50 авторов)
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@article{2021_Abdurashitov,
author = {Arkady S. Abdurashitov and Ekaterina S. Prikhozhdenko and Oksana A. Mayorova and Valentina O. Plastun and Olga I Gusliakova and Natalia A. Shushunova and Oleg A Kulikov and Valery V. Tuchin and Gleb B. Sukhorukov and Olga Sindeeva},
title = {Optical coherence microangiography of the mouse kidney for diagnosis of circulatory disorders},
journal = {Biomedical Optics Express},
year = {2021},
volume = {12},
publisher = {Optica Publishing Group},
month = {jun},
url = {https://opg.optica.org/abstract.cfm?URI=boe-12-7-4467},
number = {7},
pages = {4467},
doi = {10.1364/BOE.430393}
}
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MLA
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Abdurashitov, Arkady S., et al. “Optical coherence microangiography of the mouse kidney for diagnosis of circulatory disorders.” Biomedical Optics Express, vol. 12, no. 7, Jun. 2021, p. 4467. https://opg.optica.org/abstract.cfm?URI=boe-12-7-4467.