World Journal of Oncology, volume 10, issue 1, pages 10-27

Epidemiology of Pancreatic Cancer: Global Trends, Etiology and Risk Factors

Rawla P., Sunkara T., Gaduputi V.
Publication typeJournal Article
Publication date2019-02-26
Quartile SCImago
Q1
Quartile WOS
Impact factor4.4
ISSN19204531, 1920454X
PubMed ID:  30834048
Cancer Research
Oncology
Abstract
Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide. However, its toll is higher in more developed countries. Reasons for vast differences in mortality rates of pancreatic cancer are not completely clear yet, but it may be due to lack of appropriate diagnosis, treatment and cataloging of cancer cases. Because patients seldom exhibit symptoms until an advanced stage of the disease, pancreatic cancer remains one of the most lethal malignant neoplasms that caused 432,242 new deaths in 2018 (GLOBOCAN 2018 estimates). Globally, 458,918 new cases of pancreatic cancer have been reported in 2018, and 355,317 new cases are estimated to occur until 2040. Despite advancements in the detection and management of pancreatic cancer, the 5-year survival rate still stands at 9% only. To date, the causes of pancreatic carcinoma are still insufficiently known, although certain risk factors have been identified, such as tobacco smoking, diabetes mellitus, obesity, dietary factors, alcohol abuse, age, ethnicity, family history and genetic factors, Helicobacter pylori infection, non-O blood group and chronic pancreatitis. In general population, screening of large groups is not considered useful to detect the disease at its early stage, although newer techniques and the screening of tightly targeted groups (especially of those with family history), are being evaluated. Primary prevention is considered of utmost importance. Up-to-date statistics on pancreatic cancer occurrence and outcome along with a better understanding of the etiology and identifying the causative risk factors are essential for the primary prevention of this disease.

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GOST Copy
Rawla P., Sunkara T., Gaduputi V. Epidemiology of Pancreatic Cancer: Global Trends, Etiology and Risk Factors // World Journal of Oncology. 2019. Vol. 10. No. 1. pp. 10-27.
GOST all authors (up to 50) Copy
Rawla P., Sunkara T., Gaduputi V. Epidemiology of Pancreatic Cancer: Global Trends, Etiology and Risk Factors // World Journal of Oncology. 2019. Vol. 10. No. 1. pp. 10-27.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.14740/wjon1166
UR - https://doi.org/10.14740%2Fwjon1166
TI - Epidemiology of Pancreatic Cancer: Global Trends, Etiology and Risk Factors
T2 - World Journal of Oncology
AU - Rawla, P
AU - Sunkara, T
AU - Gaduputi, V
PY - 2019
DA - 2019/02/26 00:00:00
PB - Elmer Press, Inc.
SP - 10-27
IS - 1
VL - 10
PMID - 30834048
SN - 1920-4531
SN - 1920-454X
ER -
BibTex
Cite this
BibTex Copy
@article{2019,
author = {P Rawla and T Sunkara and V Gaduputi},
title = {Epidemiology of Pancreatic Cancer: Global Trends, Etiology and Risk Factors},
journal = {World Journal of Oncology},
year = {2019},
volume = {10},
publisher = {Elmer Press, Inc.},
month = {feb},
url = {https://doi.org/10.14740%2Fwjon1166},
number = {1},
pages = {10--27},
doi = {10.14740/wjon1166}
}
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