том 18 издание 6 страницы 1020-1026

Noninvasive Ventilatory Support of Patients with COVID-19 outside the Intensive Care Units (WARd-COVID)

Giuseppe Citerio 1, 2
Giacomo Grasselli 3, 4
Maurizio Cecconi 5, 6
Laura Antolini 1
Massimo Borelli 7
Federica De Giacomi 8
Giancarlo Bosio 8
Nicola Latronico 9, 10
Matteo Filippini 10
Marco Gemma 11
Claudia Giannotti 12
Benvenuto Antonini 13
Nicola Petrucci 14
Simone Maria Zerbi 15
Paolo Maniglia 16
Gian Paolo Castelli 17
Giovanni Marino 18
Matteo Subert 19
Giuseppe Citerio 1, 2, 20
DANILO RADRIZZANI 21
Teresa S. Mediani 22
Ferdinando Luca Lorini 23
Filippo Maria Russo 23
Angela Faletti 24
Andrea Beindorf 25
Remo Daniel Covello 26
Stefano Greco 27
Marta M. Bizzarri 28
Giuseppe Ristagno 3
Francesco Mojoli 29
Andrea Pradella 5
Paolo Severgnini 30
Marta Da Macallè 30
Andrea Albertin 31
V. MARCO RANIERI 32
Emanuele Rezoagli 1, 2, 33
Giovanni Vitale 33
Aurora Magliocca 1, 33
Gianluca Cappelleri 34
Mattia Docci 1, 35
Stefano Aliberti 4, 36
Filippo Serra 1
Emanuela Rossi 1
Maria Grazia Valsecchi 1
Antonio Pesenti 3, 4
Giuseppe Foti 1, 2
3
 
Department of Anesthesia, Intensive Care and Emergency, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
4
 
Department of Pathophysiology and Transplantation, and
5
 
Department of Anaesthesia and Intensive Care Medicine, Humanitas Clinical and Research Center Istituto di Ricovero e Cura a Carattere Scientifico Milan, Italy
7
 
Department of Anesthesia and Intensive Care Medicine, Treviglio Caravaggio Hospital, Azienda Socio-Sanitaria Territoriale Bergamo Ovest, Treviglio, Italy
8
 
Division of Pulmonary Medicine, Cremona Hospital, ASST Cremona, Cremona, Italy
13
 
Department of Anesthesiology and Intensive Care Medicine, Manerbio Hospital, and
14
 
Department of Anesthesia and Intensive Care Unit, Desenzano Hospital, Azienda Socio-Sanitaria Territoriale Garda, Brescia, Italy
16
 
Department of Anesthesia and Intensive Care Medicine, Alessandro Manzoni Hospital, Azienda Socio-Sanitaria Territoriale Lecco, Lecco, Italy
17
 
Department of Anesthesia and Intensive Care Medicine, Carlo Poma Hospital, Azienda Socio-Sanitaria Territoriale Mantova, Mantova, Italy
18
 
Department of Anesthesia and Intensive Care Medicine, Vizzolo Predabissi Hospital, and
19
 
Department of Anesthesia and Intensive Care Medicine, Melzo-Gorgonzola Hospital, Azienda Socio-Sanitaria Territoriale Melegnano e della Martesana, Melegnano, Milan, Italy
20
 
Department of Anesthesia and Intensive Care Medicine, Desio Hospital, Azienda Socio-Sanitaria Territoriale Monza, Monza e Brianza, Italy
21
 
Department of Anesthesia and Intensive Care Medicine, Legnano Hospital, Azienda Socio-Sanitaria Territoriale Ovest milanese, Legnano, Milano, Italy
22
 
Department of Anesthesia and Intensive Care Medicine, Vigevano Hospital, Azienda Socio-Sanitaria Territoriale Pavia, Vigevano, Pavia, Italy
23
 
Department of Anesthesia and Intensive Care, Azienda Socio-Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy
24
 
Department of Anesthesia and Intensive Care Medicine, Gardone Val Trompia Hospital, and
26
 
Department of Anesthesia and Intensive Care Medicine, Busto Arsizio Hospital, and
27
 
Department of Anesthesia and Intensive Care Medicine, Saronno Hospital, Azienda Socio-Sanitaria Territoriale Valle Olona, Varese, Italy
28
 
Department of Anesthesia and Intensive Care Medicine, Vimercate Hospital, Azienda Socio-Sanitaria Territoriale Vimercate, Monza e Brianza, Italy
31
 
Department of Anesthesia and Intensive Care Medicine, San Giuseppe Hospital, Milan, Italy
33
 
Policlinico San Marco, San Donato Group Hospitals, Zingonia, Bergamo, Italy
34
 
Humanitas Gavazzeni, Bergamo, Italy
35
 
Policlinico San Pietro, Ponte San Pietro, Italy; and
36
 
Foundation Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda Ospedale Maggiore Policlinico, Respiratory Unit and Cystic Fibrosis Adult Center, Milan, Italy
Тип публикацииJournal Article
Дата публикации2021-01-04
scimago Q1
wos Q1
БС1
SJR1.652
CiteScore9.6
Impact factor5.4
ISSN23256621, 23296933
Pulmonary and Respiratory Medicine
Краткое описание
Rationale: Treatment with noninvasive ventilation (NIV) in coronavirus disease (COVID-19) is frequent. Shortage of intensive care unit (ICU) beds led clinicians to deliver NIV also outside ICUs. Data about the use of NIV in COVID-19 is limited.Objectives: To describe the prevalence and clinical characteristics of patients with COVID-19 treated with NIV outside the ICUs. To investigate the factors associated with NIV failure (need for intubation or death).Methods: In this prospective, single-day observational study, we enrolled adult patients with COVID-19 who were treated with NIV outside the ICU from 31 hospitals in Lombardy, Italy.Results: We collected data on demographic and clinical characteristics, ventilatory management, and patient outcomes. Of 8,753 patients with COVID-19 present in the hospitals on the study day, 909 (10%) were receiving NIV outside the ICU. A majority of patients (778/909; 85%) patients were treated with continuous positive airway pressure (CPAP), which was delivered by helmet in 617 (68%) patients. NIV failed in 300 patients (37.6%), whereas 498 (62.4%) patients were discharged alive without intubation. Overall mortality was 25%. NIV failure occurred in 152/284 (53%) patients with an arterial oxygen pressure (PaO2)/fraction of inspired oxygen (FiO2) ratio 60% and close to 75% in full-treatment patients. C-reactive protein, PaO2/FiO2, and platelet counts were independently associated with increased risk of NIV failure.Clinical trial registered with ClinicalTrials.gov (NCT04382235).
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Citerio G. et al. Noninvasive Ventilatory Support of Patients with COVID-19 outside the Intensive Care Units (WARd-COVID) // Annals of the American Thoracic Society. 2021. Vol. 18. No. 6. pp. 1020-1026.
ГОСТ со всеми авторами (до 50) Скопировать
Citerio G. et al. Noninvasive Ventilatory Support of Patients with COVID-19 outside the Intensive Care Units (WARd-COVID) // Annals of the American Thoracic Society. 2021. Vol. 18. No. 6. pp. 1020-1026.
RIS |
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TY - JOUR
DO - 10.1513/AnnalsATS.202008-1080OC
UR - https://doi.org/10.1513/AnnalsATS.202008-1080OC
TI - Noninvasive Ventilatory Support of Patients with COVID-19 outside the Intensive Care Units (WARd-COVID)
T2 - Annals of the American Thoracic Society
AU - Citerio, Giuseppe
AU - Grasselli, Giacomo
AU - Cecconi, Maurizio
AU - Antolini, Laura
AU - Borelli, Massimo
AU - De Giacomi, Federica
AU - Bosio, Giancarlo
AU - Latronico, Nicola
AU - Filippini, Matteo
AU - Gemma, Marco
AU - Giannotti, Claudia
AU - Antonini, Benvenuto
AU - Petrucci, Nicola
AU - Zerbi, Simone Maria
AU - Maniglia, Paolo
AU - Castelli, Gian Paolo
AU - Marino, Giovanni
AU - Subert, Matteo
AU - Citerio, Giuseppe
AU - RADRIZZANI, DANILO
AU - Mediani, Teresa S.
AU - Lorini, Ferdinando Luca
AU - Russo, Filippo Maria
AU - Faletti, Angela
AU - Beindorf, Andrea
AU - Covello, Remo Daniel
AU - Greco, Stefano
AU - Bizzarri, Marta M.
AU - Ristagno, Giuseppe
AU - Mojoli, Francesco
AU - Pradella, Andrea
AU - Severgnini, Paolo
AU - Da Macallè, Marta
AU - Albertin, Andrea
AU - RANIERI, V. MARCO
AU - Rezoagli, Emanuele
AU - Vitale, Giovanni
AU - Magliocca, Aurora
AU - Cappelleri, Gianluca
AU - Docci, Mattia
AU - Aliberti, Stefano
AU - Serra, Filippo
AU - Rossi, Emanuela
AU - Valsecchi, Maria Grazia
AU - Pesenti, Antonio
AU - Foti, Giuseppe
PY - 2021
DA - 2021/01/04
PB - American Thoracic Society
SP - 1020-1026
IS - 6
VL - 18
PMID - 33395553
SN - 2325-6621
SN - 2329-6933
ER -
BibTex |
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@article{2021_Citerio,
author = {Giuseppe Citerio and Giacomo Grasselli and Maurizio Cecconi and Laura Antolini and Massimo Borelli and Federica De Giacomi and Giancarlo Bosio and Nicola Latronico and Matteo Filippini and Marco Gemma and Claudia Giannotti and Benvenuto Antonini and Nicola Petrucci and Simone Maria Zerbi and Paolo Maniglia and Gian Paolo Castelli and Giovanni Marino and Matteo Subert and Giuseppe Citerio and DANILO RADRIZZANI and Teresa S. Mediani and Ferdinando Luca Lorini and Filippo Maria Russo and Angela Faletti and Andrea Beindorf and Remo Daniel Covello and Stefano Greco and Marta M. Bizzarri and Giuseppe Ristagno and Francesco Mojoli and Andrea Pradella and Paolo Severgnini and Marta Da Macallè and Andrea Albertin and V. MARCO RANIERI and Emanuele Rezoagli and Giovanni Vitale and Aurora Magliocca and Gianluca Cappelleri and Mattia Docci and Stefano Aliberti and Filippo Serra and Emanuela Rossi and Maria Grazia Valsecchi and Antonio Pesenti and Giuseppe Foti and others},
title = {Noninvasive Ventilatory Support of Patients with COVID-19 outside the Intensive Care Units (WARd-COVID)},
journal = {Annals of the American Thoracic Society},
year = {2021},
volume = {18},
publisher = {American Thoracic Society},
month = {jan},
url = {https://doi.org/10.1513/AnnalsATS.202008-1080OC},
number = {6},
pages = {1020--1026},
doi = {10.1513/AnnalsATS.202008-1080OC}
}
MLA
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Citerio, Giuseppe, et al. “Noninvasive Ventilatory Support of Patients with COVID-19 outside the Intensive Care Units (WARd-COVID).” Annals of the American Thoracic Society, vol. 18, no. 6, Jan. 2021, pp. 1020-1026. https://doi.org/10.1513/AnnalsATS.202008-1080OC.