Walter de Gruyter
Journal of Perinatal Medicine
,  том 50 ,  издание 8 ,  страницы 1067-1072

Effect of combined paracetamol and dexamethasone vs. paracetamol on postoperative nausea vomiting after cesarean section

Тип публикации: Journal Article
Дата публикации: 2022-05-20
Walter de Gruyter
scimago Q2
wos Q3
БС1
SJR: 0.592
CiteScore: 3.5
Impact factor: 1.4
ISSN: 03005577, 16193997
Obstetrics and Gynecology
Pediatrics, Perinatology and Child Health
Краткое описание
Objectives

Postoperative nausea and vomiting (PONV) are common symptoms after cesarean delivery (CD) that affect patients outcomes and satisfaction. The treatment of choice is still evolving, therefore, we aimed to evaluate PONV of combined paracetamol-dexamethasone vs. paracetamol alone.
Methods

This study is a double-blind randomized controlled trial on 100 patients undergoing cesarean delivery. Participants were randomly assigned into two groups of paracetamol or combined paracetamol-dexamethasone. Nausea and vomiting score, VAS score of pain, and chill were compared between the two groups.
Results

The result of this study found that mild nausea 2nd h after surgery in the combined group was lesser than paracetamol group (0.03). However, there was no statistically significant difference in nausea and vomiting score in other periods of time between the two groups. VAS score of pain decreased 12th and 6th h after the surgery in the combined and paracetamol group, respectively. Chilling occurred in two patients of combined group and four patients of paracetamol group (p=0.432).
Conclusions

Dexamethasone added to paracetamol might not improve pain and vomiting after cesarean delivery comparison with just paracetamol. But it can be effective for reducing the score of nausea after the surgery.

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Bozorgmanesh M. et al. Effect of combined paracetamol and dexamethasone vs. paracetamol on postoperative nausea vomiting after cesarean section // Journal of Perinatal Medicine. 2022. Vol. 50. No. 8. pp. 1067-1072.
ГОСТ со всеми авторами (до 50) Скопировать
Bozorgmanesh M., Valibeik S., Shokrpour M., Maktabi M., Kamali A. Effect of combined paracetamol and dexamethasone vs. paracetamol on postoperative nausea vomiting after cesarean section // Journal of Perinatal Medicine. 2022. Vol. 50. No. 8. pp. 1067-1072.
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TY - JOUR
DO - 10.1515/jpm-2021-0644
UR - https://doi.org/10.1515/jpm-2021-0644
TI - Effect of combined paracetamol and dexamethasone vs. paracetamol on postoperative nausea vomiting after cesarean section
T2 - Journal of Perinatal Medicine
AU - Bozorgmanesh, Mohammadreza
AU - Valibeik, Shamim
AU - Shokrpour, Maryam
AU - Maktabi, Maryam
AU - Kamali, Alireza
PY - 2022
DA - 2022/05/20
PB - Walter de Gruyter
SP - 1067-1072
IS - 8
VL - 50
PMID - 35589674
SN - 0300-5577
SN - 1619-3997
ER -
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@article{2022_Bozorgmanesh,
author = {Mohammadreza Bozorgmanesh and Shamim Valibeik and Maryam Shokrpour and Maryam Maktabi and Alireza Kamali},
title = {Effect of combined paracetamol and dexamethasone vs. paracetamol on postoperative nausea vomiting after cesarean section},
journal = {Journal of Perinatal Medicine},
year = {2022},
volume = {50},
publisher = {Walter de Gruyter},
month = {may},
url = {https://doi.org/10.1515/jpm-2021-0644},
number = {8},
pages = {1067--1072},
doi = {10.1515/jpm-2021-0644}
}
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Bozorgmanesh, Mohammadreza, et al. “Effect of combined paracetamol and dexamethasone vs. paracetamol on postoperative nausea vomiting after cesarean section.” Journal of Perinatal Medicine, vol. 50, no. 8, May. 2022, pp. 1067-1072. https://doi.org/10.1515/jpm-2021-0644.