Open Access

EMBO Journal, volume 40, issue 19

Autophagy in major human diseases

Daniel J. Klionsky ¹

Giulia Petroni ²

Ravi K. Amaravadi ^{3, 4}

Eric H. Baehrecke ⁵

Andrea Ballabio ^{6, 7, 8}

Patricia Boya ⁹

José Manuel Bravo-San Pedro ^{10, 11}

Ken Cadwell ^{12, 13, 14}

F. Cecconi ^{15, 16, 17}

Augustine M.K. Choi ^{18, 19}

Mary E. Choi ^{19, 20}

Charleen T Chu ²¹

Patrice Codogno ^{22, 23}

Maria Isabel Colombo ²⁴

Ana Maria Cuervo ^{25, 26}

Vojo Deretic ^{27, 28}

Ivan Dikic ^{29, 30}

Zvulun Elazar ³¹

Eeva‐Liisa Eskelinen ³²

Gian Maria Fimia ^{33, 34}

David A. Gewirtz ³⁵

Douglas R. Green ³⁶

Malene Hansen ³⁷

Marja Jaattela ^{38, 39}

Terje Johansen ⁴⁰

Gábor Juhász ^{41, 42}

Vassiliki Karantza ⁴³

Claudine Kraft ^{44, 45}

Guido Kroemer ^{46, 47, 48, 49, 50}

Nicholas T. KTISTAKIS ⁵¹

Sharad Kumar ^{52, 53}

C. López-Otín ^{54, 55}

Kay F Macleod ^{56, 57}

Frank Madeo ^{58, 59, 60}

Jennifer Martinez ⁶¹

Alicia Meléndez ^{62, 63}

NOBORU MIZUSHIMA ⁶⁴

C Münz ⁶⁵

Josef M. Penninger ^{66, 67}

Rushika M Perera ^{68, 69, 70}

M. Piacentini ^{71, 72}

Fulvio Reggiori ⁷³

David C. Rubinsztein ^{74, 75}

Kevin M. Ryan ^{76, 77}

Junichi Sadoshima ⁷⁸

Laura Santambrogio ^{2, 79, 80}

Luca Scorrano ^{81, 82}

Hans-Uwe Simon ^{83, 84, 85}

Anna Katharina Simon ⁸⁶

Anne Simonsen ^{87, 88, 89}

Alexandra Stolz ^{29, 30}

Nektarios Tavernarakis ^{90, 91}

Sharon A Tooze ⁹²

Tamotsu Yoshimori ^{93, 94, 95}

Junying Yuan ^{96, 97}

Zhenyu Yue ⁹⁸

Qing Zhong Qing Zhong ⁹⁹

Lorenzo Galluzzi ^{2, 23, 79, 80, 100}

Federico Pietrocola ¹⁰¹

Show full list: 59 authors

Hide authors affiliations

Life Sciences Institute University of Michigan Ann Arbor MI USA |

Department of Radiation Oncology Weill Cornell Medical College New York NY USA |

Department of Medicine University of Pennsylvania Philadelphia PA USA |

⁴

Abramson Cancer Center University of Pennsylvania Philadelphia PA USA |

⁵

Department of Molecular, Cell and Cancer Biology University of Massachusetts Medical School Worcester MA USA |

⁶

Telethon Institute of Genetics and Medicine Pozzuoli Italy |

⁷

Department of Translational Medical Sciences Section of Pediatrics Federico II University Naples Italy |

⁸

Department of Molecular and Human Genetics Baylor College of Medicine, and Jan and Dan Duncan Neurological Research Institute Texas Children Hospital Houston TX USA

⁹

Margarita Salas Center for Biological Research Spanish National Research Council Madrid Spain |

¹⁰

Faculty of Medicine Department Section of Physiology Complutense University of Madrid Madrid Spain |

¹¹

Center for Networked Biomedical Research in Neurodegenerative Diseases (CIBERNED) Madrid Spain |

¹²

Kimmel Center for Biology and Medicine at the Skirball Institute New York University Grossman School of Medicine New York NY USA |

¹³

Department of Microbiology New York University Grossman School of Medicine New York NY USA |

¹⁴

Division of Gastroenterology and Hepatology Department of Medicine New York University Langone Health New York NY USA |

¹⁵

Cell Stress and Survival Unit Center for Autophagy, Recycling and Disease (CARD) Danish Cancer Society Research Center Copenhagen Denmark |

¹⁶

Department of Pediatric Onco‐Hematology and Cell and Gene Therapy IRCCS Bambino Gesù Children's Hospital Rome Italy |

¹⁷

Department of Biology University of Rome ‘Tor Vergata’ Rome Italy |

¹⁸

Division of Pulmonary and Critical Care Medicine Joan and Sanford I. Weill Department of Medicine Weill Cornell Medicine New York NY USA |

¹⁹

New York‐Presbyterian Hospital Weill Cornell Medicine New York NY USA

²⁰

Division of Nephrology and Hypertension Joan and Sanford I. Weill Department of Medicine Weill Cornell Medicine New York NY USA |

²¹

Department of Pathology University of Pittsburgh School of Medicine Pittsburgh PA USA |

²²

Institut Necker‐Enfants Malades INSERM U1151‐CNRS UMR 8253 Paris France |

²³

Université de Paris Paris France |

²⁴

Laboratorio de Mecanismos Moleculares Implicados en el Tráfico Vesicular y la Autofagia‐Instituto de Histología y Embriología (IHEM)‐Universidad Nacional de Cuyo CONICET‐ Facultad de Ciencias Médicas Mendoza Argentina |

²⁵

Department of Developmental and Molecular Biology Albert Einstein College of Medicine Bronx NY USA |

²⁶

Institute for Aging Studies Albert Einstein College of Medicine Bronx NY USA |

²⁷

Autophagy Inflammation and Metabolism (AIM Center of Biomedical Research Excellence University of New Mexico Health Sciences Center Albuquerque NM USA |

²⁸

Department of Molecular Genetics and Microbiology University of New Mexico Health Sciences Center Albuquerque NM USA |

²⁹

Institute of Biochemistry II School of Medicine Goethe University Frankfurt, Frankfurt am Main Germany |

³⁰

Buchmann Institute for Molecular Life Sciences Goethe University Frankfurt, Frankfurt am Main Germany |

³¹

Department of Biomolecular Sciences The Weizmann Institute of Science Rehovot Israel |

³²

Institute of Biomedicine University of Turku Turku Finland |

³³

Department of Molecular Medicine Sapienza University of Rome Rome Italy |

³⁴

Department of Epidemiology Preclinical Research, and Advanced Diagnostics National Institute for Infectious Diseases ‘L. Spallanzani’ IRCCS Rome Italy |

³⁵

Department of Pharmacology and Toxicology School of Medicine Virginia Commonwealth University Richmond VA USA |

³⁶

Department of Immunology St. Jude Children's Research Hospital Memphis TN USA |

³⁷

Sanford Burnham Prebys Medical Discovery Institute Program of Development Aging, and Regeneration La Jolla CA USA |

³⁸

Cell Death and Metabolism Center for Autophagy, Recycling & Disease Danish Cancer Society Research Center Copenhagen Denmark |

³⁹

Department of Cellular and Molecular Medicine Faculty of Health Sciences University of Copenhagen Copenhagen Denmark |

⁴⁰

Department of Medical Biology Molecular Cancer Research Group University of Tromsø—The Arctic University of Norway Tromsø Norway |

⁴¹

Institute of Genetics Biological Research Center Szeged Hungary |

⁴²

Department of Anatomy, Cell and Developmental Biology Eötvös Loránd University Budapest Hungary |

⁴³

Merck & Co., Inc. Kenilworth NJ USA |

⁴⁴

Institute of Biochemistry and Molecular Biology ZBMZ Faculty of Medicine University of Freiburg Freiburg Germany |

⁴⁵

CIBSS ‐ Centre for Integrative Biological Signalling Studies University of Freiburg Freiburg Germany |

⁴⁶

Centre de Recherche des Cordeliers Equipe Labellisée par la Ligue Contre le Cancer Université de Paris Sorbonne Université Inserm U1138 Institut Universitaire de France Paris France

⁴⁷

Metabolomics and Cell Biology Platforms Institut Gustave Roussy Villejuif France |

⁴⁸

Pôle de Biologie Hôpital Européen Georges Pompidou AP‐HP Paris France |

⁴⁹

Suzhou Institute for Systems Medicine Chinese Academy of Medical Sciences Suzhou China |

⁵⁰

Karolinska Institute Department of Women's and Children's Health Karolinska University Hospital Stockholm Sweden

⁵¹

Signalling programme Babraham Institute Cambridge UK |

⁵²

Centre for Cancer Biology University of South Australia Adelaide SA Australia |

⁵³

Faculty of Health and Medical Sciences University of Adelaide Adelaide SA Australia |

⁵⁴

Departamento de Bioquímica y Biología Molecular Facultad de Medicina Instituto Universitario de Oncología del Principado de Asturias (IUOPA) Universidad de Oviedo Oviedo Spain |

⁵⁵

Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) Madrid Spain |

⁵⁶

The Ben May Department for Cancer Research The Gordon Center for Integrative Sciences W‐338 The University of Chicago Chicago IL USA |

⁵⁷

The University of Chicago Chicago IL USA |

⁵⁸

Institute of Molecular Biosciences NAWI Graz University of Graz Graz Austria |

⁵⁹

BioTechMed‐Graz Graz Austria |

⁶⁰

Field of Excellence BioHealth – University of Graz Graz Austria |

⁶¹

Immunity, Inflammation and Disease Laboratory National Institute of Environmental Health Sciences NIH Research Triangle Park NC USA |

⁶²

Biology Department, Queens College City University of New York Flushing NY USA |

⁶³

The Graduate Center Biology and Biochemistry PhD Programs of the City University of New York New York NY USA |

⁶⁴

Department of Biochemistry and Molecular Biology Graduate School of Medicine The University of Tokyo Tokyo Japan |

⁶⁵

Viral Immunobiology Institute of Experimental Immunology University of Zurich Zurich Switzerland |

⁶⁶

Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) Vienna Biocenter (VBC) Vienna Austria |

⁶⁷

Department of Medical Genetics Life Sciences Institute University of British Columbia Vancouver BC Canada |

⁶⁸

Department of Anatomy University of California, San Francisco San Francisco CA USA |

⁶⁹

Department of Pathology University of California, San Francisco San Francisco CA USA |

⁷⁰

Helen Diller Family Comprehensive Cancer Center University of California, San Francisco San Francisco CA USA |

⁷¹

Department of Biology University of Rome “Tor Vergata” Rome Italy |

⁷²

Laboratory of Molecular Medicine Institute of Cytology Russian Academy of Science Saint Petersburg Russia |

⁷³

Department of Biomedical Sciences of Cells & Systems Molecular Cell Biology Section University of Groningen University Medical Center Groningen Groningen The Netherlands |

⁷⁴

Department of Medical Genetics Cambridge Institute for Medical Research University of Cambridge Cambridge UK |

⁷⁵

UK Dementia Research Institute University of Cambridge Cambridge UK |

⁷⁶

Cancer Research UK Beatson Institute Glasgow UK |

⁷⁷

Institute of Cancer Sciences University of Glasgow Glasgow UK |

⁷⁸

Department of Cell Biology and Molecular Medicine Cardiovascular Research Institute Rutgers New Jersey Medical School Newark NJ USA |

⁷⁹

Sandra and Edward Meyer Cancer Center New York NY USA |

⁸⁰

Caryl and Israel Englander Institute for Precision Medicine New York NY USA |

⁸¹

Istituto Veneto di Medicina Molecolare Padova Italy |

⁸²

Department of Biology University of Padova Padova Italy |

⁸³

Institute of Pharmacology University of Bern Bern Switzerland |

⁸⁴

Department of Clinical Immunology and Allergology Sechenov University Moscow Russia |

⁸⁵

Laboratory of Molecular Immunology Institute of Fundamental Medicine and Biology Kazan Federal University Kazan Russia |

⁸⁶

The Kennedy Institute of Rheumatology NDORMS University of Oxford Oxford UK |

⁸⁷

Department of Molecular Medicine Institute of Basic Medical Sciences University of Oslo Oslo Norway |

⁸⁸

Centre for Cancer Cell Reprogramming Institute of Clinical Medicine University of Oslo Oslo Norway |

⁸⁹

Department of Molecular Cell Biology Institute for Cancer Research Oslo University Hospital Montebello Oslo Norway |

⁹⁰

Institute of Molecular Biology and Biotechnology Foundation for Research and Technology‐Hellas Heraklion, Crete Greece |

⁹¹

Department of Basic Sciences School of Medicine University of Crete Heraklion, Crete Greece |

⁹²

Molecular Cell Biology of Autophagy The Francis Crick Institute London UK |

⁹³

Department of Genetics Graduate School of Medicine Osaka University Suita Japan |

⁹⁴

Department of Intracellular Membrane Dynamics Graduate School of Frontier Biosciences Osaka University Suita Japan |

⁹⁵

Integrated Frontier Research for Medical Science Division Institute for Open and Transdisciplinary Research Initiatives (OTRI) Osaka University Suita Japan |

⁹⁶

Interdisciplinary Research Center on Biology and Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai China |

⁹⁷

Department of Cell Biology Harvard Medical School Boston MA USA |

⁹⁸

Department of Neurology Friedman Brain Institute Icahn School of Medicine at Mount Sinai New York NY USA |

⁹⁹

Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education Department of Pathophysiology Shanghai Jiao Tong University School of Medicine (SJTU‐SM) Shanghai China |

¹⁰⁰

Department of Dermatology Yale School of Medicine New Haven CT USA |

¹⁰¹

Department of Biosciences and Nutrition Karolinska Institute Huddinge Sweden |

Publication type: Journal Article

Publication date: 2021-08-30

European Molecular Biology Organization

Journal: EMBO Journal

scimago Q1

wos Q1

SJR: 5.489

CiteScore: 18.9

Impact factor: 9.4

ISSN: 02614189, 14602075

DOI: 10.15252/embj.2021108863

Copy DOI

General Biochemistry, Genetics and Molecular Biology

Molecular Biology

General Immunology and Microbiology

General Neuroscience

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