Open Access

EMBO Journal

, volume 41 , issue 21

A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A

Matt C. Simon ¹

Jiping Yang ²

Jonathan Gigas ¹

Eric Jay Earley ³

Eric Hillpot ¹

Lei Zhang ⁴

Maria Zagorulya ¹

Greg Tombline ¹

Michael Gilbert ⁵

Samantha L. Yuen ⁴

Alexis Pope ²

Michael Van Meter ¹

Stephan Emmrich ¹

Denis Firsanov ¹

Advait Athreya ¹

Seyed Ali Biashad ¹

Jeehae Han ⁶

Seungjin Ryu ⁶

Archana Tare ⁶

Yizhou Zhu ⁶

Adam Hudgins ⁶

Gil Atzmon ^{6, 7}

Nir Barzilai ⁶

Aaron Wolfe ⁸

Kelsey Moody ⁸

Benjamin A. Garcia ⁵

David D Thomas ⁴

Paul D. Robbins ⁴

Jan Vijg ⁶

Andrei Seluanov ¹

Yousin Suh ²

Vera Gorbunova ¹

Hide authors affiliations Show authors affiliations: 8 affiliations

Department of Biology University of Rochester Rochester NY USA |

Department of Obstetrics and Gynecology Columbia University New York NY USA |

Biostatistics and Epidemiology RTI International Durham NC USA |

⁴

Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism University of Minnesota Minneapolis MN USA |

⁵

Department of Biochemistry and Biophysics, Perelman School of Medicine University of Pennsylvania Philadelphia PA USA |

⁶

Department of Genetics Albert Einstein College of Medicine Bronx NY USA |

⁷

Department of Biology, Faculty of Natural Sciences University of Haifa Haifa Israel |

⁸

Ichor Therapeutics Lafayette NY USA |

Publication type: Journal Article

Publication date: 2022-10-10

European Molecular Biology Organization

EMBO Journal

scimago Q1

wos Q1

SJR: 4.821

CiteScore: 16.8

Impact factor: 8.3

ISSN: 02614189, 14602075

DOI: 10.15252/embj.2021110393

Copy DOI

PubMed ID: 36215696

General Biochemistry, Genetics and Molecular Biology

Molecular Biology

General Immunology and Microbiology

General Neuroscience

Found

1 citation

Perepechenov Stefan

2 publications

h-index: 1

Kazan Federal University

Research interests

Cell biology

Molecular Biology

Regenerative medicine

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GOST |

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GOST Copy

Simon M. C. et al. A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A // EMBO Journal. 2022. Vol. 41. No. 21.

GOST all authors (up to 50) Copy

Simon M. C., Yang J., Gigas J., Earley E. J., Hillpot E., Zhang L., Zagorulya M., Tombline G., Gilbert M., Yuen S. L., Pope A., Van Meter M., Emmrich S., Firsanov D., Athreya A., Biashad S. A., Han J., Ryu S., Tare A., Zhu Y., Hudgins A., Atzmon G., Barzilai N., Wolfe A., Moody K., Garcia B. A., Thomas D. D., Robbins P. D., Vijg J., Seluanov A., Suh Y., Gorbunova V. A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A // EMBO Journal. 2022. Vol. 41. No. 21.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.15252/embj.2021110393

UR - https://doi.org/10.15252/embj.2021110393

TI - A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A

T2 - EMBO Journal

AU - Simon, Matt C.

AU - Yang, Jiping

AU - Gigas, Jonathan

AU - Earley, Eric Jay

AU - Hillpot, Eric

AU - Zhang, Lei

AU - Zagorulya, Maria

AU - Tombline, Greg

AU - Gilbert, Michael

AU - Yuen, Samantha L.

AU - Pope, Alexis

AU - Van Meter, Michael

AU - Emmrich, Stephan

AU - Firsanov, Denis

AU - Athreya, Advait

AU - Biashad, Seyed Ali

AU - Han, Jeehae

AU - Ryu, Seungjin

AU - Tare, Archana

AU - Zhu, Yizhou

AU - Hudgins, Adam

AU - Atzmon, Gil

AU - Barzilai, Nir

AU - Wolfe, Aaron

AU - Moody, Kelsey

AU - Garcia, Benjamin A.

AU - Thomas, David D

AU - Robbins, Paul D.

AU - Vijg, Jan

AU - Seluanov, Andrei

AU - Suh, Yousin

AU - Gorbunova, Vera

PY - 2022

DA - 2022/10/10

PB - European Molecular Biology Organization

IS - 21

VL - 41

PMID - 36215696

SN - 0261-4189

SN - 1460-2075

ER -

BibTex

Cite this

BibTex (up to 50 authors) Copy

@article{2022_Simon,

author = {Matt C. Simon and Jiping Yang and Jonathan Gigas and Eric Jay Earley and Eric Hillpot and Lei Zhang and Maria Zagorulya and Greg Tombline and Michael Gilbert and Samantha L. Yuen and Alexis Pope and Michael Van Meter and Stephan Emmrich and Denis Firsanov and Advait Athreya and Seyed Ali Biashad and Jeehae Han and Seungjin Ryu and Archana Tare and Yizhou Zhu and Adam Hudgins and Gil Atzmon and Nir Barzilai and Aaron Wolfe and Kelsey Moody and Benjamin A. Garcia and David D Thomas and Paul D. Robbins and Jan Vijg and Andrei Seluanov and Yousin Suh and Vera Gorbunova},

title = {A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A},

journal = {EMBO Journal},

year = {2022},

volume = {41},

publisher = {European Molecular Biology Organization},

month = {oct},

url = {https://doi.org/10.15252/embj.2021110393},

number = {21},

doi = {10.15252/embj.2021110393}

}

Publisher

European Molecular Biology Organization

Journal

EMBO Journal

scimago Q1

wos Q1

SJR

4.821

CiteScore

16.8

Impact factor

8.3

ISSN

02614189 (Print)

14602075 (Electronic)