Open Access
Immunotherapy in mucosal melanoma: a case report and review of the literature
HANA ŠTUDENTOVÁ
1
,
Hana Kalabova
1
,
Pavel Koranda
2
,
Karin Chytilova
3
,
Ladislava Kucerova
4
,
Bohuslav MELICHAR
1, 5
,
David Vrana
1
Publication type: Journal Article
Publication date: 2018-04-02
PubMed ID:
29707161
Oncology
Abstract
Mucosal melanoma is a rare form of melanoma presenting variably as sores or unexplained bleeding located mainly in the head and neck region, anorectal region or female genital tract. Mucosal melanoma is usually diagnosed at an advanced stage and is characterized by an aggressive behavior. Surgery represents the mainstay of treatment for early stage melanomas, but for advanced disease there have been until recently very limited treatment options. Ipilimumab, a human monoclonal antibody directed against the cytotoxic T lymphocyte antigen 4, was the first treatment modality to demonstrate survival benefit in advanced malignant melanoma.Description of a new case and review of the literature.We present here a patient with mucosal melanoma with aggressive biological behavior and documented late response to ipilimumab.Ipilimumab represents an effective treatment option in selected patients with mucosal melanoma.
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GOST
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ŠTUDENTOVÁ H. et al. Immunotherapy in mucosal melanoma: a case report and review of the literature // Oncotarget. 2018. Vol. 9. No. 25. pp. 17971-17977.
GOST all authors (up to 50)
Copy
ŠTUDENTOVÁ H., Kalabova H., Koranda P., Chytilova K., Kucerova L., MELICHAR B., Vrana D. Immunotherapy in mucosal melanoma: a case report and review of the literature // Oncotarget. 2018. Vol. 9. No. 25. pp. 17971-17977.
Cite this
RIS
Copy
TY - JOUR
DO - 10.18632/oncotarget.24727
UR - https://doi.org/10.18632/oncotarget.24727
TI - Immunotherapy in mucosal melanoma: a case report and review of the literature
T2 - Oncotarget
AU - ŠTUDENTOVÁ, HANA
AU - Kalabova, Hana
AU - Koranda, Pavel
AU - Chytilova, Karin
AU - Kucerova, Ladislava
AU - MELICHAR, Bohuslav
AU - Vrana, David
PY - 2018
DA - 2018/04/02
PB - Impact Journals
SP - 17971-17977
IS - 25
VL - 9
PMID - 29707161
SN - 1949-2553
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2018_ŠTUDENTOVÁ,
author = {HANA ŠTUDENTOVÁ and Hana Kalabova and Pavel Koranda and Karin Chytilova and Ladislava Kucerova and Bohuslav MELICHAR and David Vrana},
title = {Immunotherapy in mucosal melanoma: a case report and review of the literature},
journal = {Oncotarget},
year = {2018},
volume = {9},
publisher = {Impact Journals},
month = {apr},
url = {https://doi.org/10.18632/oncotarget.24727},
number = {25},
pages = {17971--17977},
doi = {10.18632/oncotarget.24727}
}
Cite this
MLA
Copy
ŠTUDENTOVÁ, HANA, et al. “Immunotherapy in mucosal melanoma: a case report and review of the literature.” Oncotarget, vol. 9, no. 25, Apr. 2018, pp. 17971-17977. https://doi.org/10.18632/oncotarget.24727.