Acquired von Willebrand Syndrome in a Patient with Multiple Comorbidities, Including MALT Lymphoma with IgA Monoclonal Gammopathy and Hyperviscosity Syndrome
Mai Owari
1
,
Kayo Harada-Shirado
1
,
Ryuichi Togawa
2
,
Masahiko Fukatsu
1
,
Yuki Sato
1
,
Koichiro Fukuchi
1
,
Mamiko Endo
1
,
Hiroshi Takahashi
1
,
Satoshi Kimura
1
,
Tsukasa Osaki
3
,
Masayoshi Souri
4
,
Akitada ICHINOSE
3
,
Yoko Shibata
2
,
Yuko Hashimoto
5
,
Takayuki Ikezoe
1
3
The Japanese Collaborative Research Group (JCRG) on Acquired Coagulopathies supported by the Japanese Ministry of Health, Labor, and Welfare, Japan
|
Тип публикации: Journal Article
Дата публикации: 2023-02-15
scimago Q3
wos Q2
БС2
SJR: 0.328
CiteScore: 1.8
Impact factor: 1.1
ISSN: 09182918, 13497235, 12205818
PubMed ID:
35871597
General Medicine
Internal Medicine
Краткое описание
Acquired von Willebrand syndrome (aVWS) develops with various underlying diseases. We herein report an individual with aVWS associated with mucosa-associated lymphoid tissue lymphoma in the lungs complicated by hyperviscosity syndrome, Sjögren's syndrome, and hypothyroidism. This patient developed life-threatening hemorrhaging during a lung biopsy despite transfusion of concentrate of plasma-derived VWF/factor VIII. The use of rituximab caused remission of the lymphoma and hyperviscosity syndrome in parallel with the resolution of aVWS. Thus, lymphoma and hyperviscosity might result in aVWS. Invasive procedures with a risk of bleeding should be avoided in individuals with aVWS.
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Owari M. et al. Acquired von Willebrand Syndrome in a Patient with Multiple Comorbidities, Including MALT Lymphoma with IgA Monoclonal Gammopathy and Hyperviscosity Syndrome // Internal Medicine. 2023. Vol. 62. No. 4. pp. 605-611.
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Owari M., Harada-Shirado K., Togawa R., Fukatsu M., Sato Y., Fukuchi K., Endo M., Takahashi H., Kimura S., Osaki T., Souri M., ICHINOSE A., Shibata Y., Hashimoto Y., Ikezoe T. Acquired von Willebrand Syndrome in a Patient with Multiple Comorbidities, Including MALT Lymphoma with IgA Monoclonal Gammopathy and Hyperviscosity Syndrome // Internal Medicine. 2023. Vol. 62. No. 4. pp. 605-611.
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TY - JOUR
DO - 10.2169/internalmedicine.9815-22
UR - https://doi.org/10.2169/internalmedicine.9815-22
TI - Acquired von Willebrand Syndrome in a Patient with Multiple Comorbidities, Including MALT Lymphoma with IgA Monoclonal Gammopathy and Hyperviscosity Syndrome
T2 - Internal Medicine
AU - Owari, Mai
AU - Harada-Shirado, Kayo
AU - Togawa, Ryuichi
AU - Fukatsu, Masahiko
AU - Sato, Yuki
AU - Fukuchi, Koichiro
AU - Endo, Mamiko
AU - Takahashi, Hiroshi
AU - Kimura, Satoshi
AU - Osaki, Tsukasa
AU - Souri, Masayoshi
AU - ICHINOSE, Akitada
AU - Shibata, Yoko
AU - Hashimoto, Yuko
AU - Ikezoe, Takayuki
PY - 2023
DA - 2023/02/15
PB - Japanese Society of Internal Medicine
SP - 605-611
IS - 4
VL - 62
PMID - 35871597
SN - 0918-2918
SN - 1349-7235
SN - 1220-5818
ER -
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@article{2023_Owari,
author = {Mai Owari and Kayo Harada-Shirado and Ryuichi Togawa and Masahiko Fukatsu and Yuki Sato and Koichiro Fukuchi and Mamiko Endo and Hiroshi Takahashi and Satoshi Kimura and Tsukasa Osaki and Masayoshi Souri and Akitada ICHINOSE and Yoko Shibata and Yuko Hashimoto and Takayuki Ikezoe},
title = {Acquired von Willebrand Syndrome in a Patient with Multiple Comorbidities, Including MALT Lymphoma with IgA Monoclonal Gammopathy and Hyperviscosity Syndrome},
journal = {Internal Medicine},
year = {2023},
volume = {62},
publisher = {Japanese Society of Internal Medicine},
month = {feb},
url = {https://doi.org/10.2169/internalmedicine.9815-22},
number = {4},
pages = {605--611},
doi = {10.2169/internalmedicine.9815-22}
}
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MLA
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Owari, Mai, et al. “Acquired von Willebrand Syndrome in a Patient with Multiple Comorbidities, Including MALT Lymphoma with IgA Monoclonal Gammopathy and Hyperviscosity Syndrome.” Internal Medicine, vol. 62, no. 4, Feb. 2023, pp. 605-611. https://doi.org/10.2169/internalmedicine.9815-22.