Medicinal Chemistry Aspects of Isoxazole Analogues as Anti-tubercular Agents
Publication type: Journal Article
Publication date: 2023-08-01
scimago Q3
wos Q3
SJR: 0.356
CiteScore: 4.0
Impact factor: 2.1
ISSN: 13852728, 18755348
Organic Chemistry
Abstract
Abstract:
Tuberculosis (TB) is the major cause of mortality around the world and one of the most common diseases linked to AIDS. Due to the emergence of multi-drug resistance, extensive drug resistance, and total drug resistance strains, TB has become a difficult disease to treat. Isoxazole scaffold shows a wide range of biological activities, including anticancer, antibacterial, anti-tubercular, antiviral, and anti-inflammatory activities etc. Several isoxazole derivatives have been produced and few of them have shown comparable anti-tubercular activity with standard drugs. In this review, we have focused on reported isoxazole derivatives having antitubercular activity and summarized their structure-activity relationship.
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Singh H. et al. Medicinal Chemistry Aspects of Isoxazole Analogues as Anti-tubercular Agents // Current Organic Chemistry. 2023. Vol. 27. No. 15. pp. 1308-1318.
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Singh H., Kumari V. A., Singh A. K., Kumar A., Kumar P. Medicinal Chemistry Aspects of Isoxazole Analogues as Anti-tubercular Agents // Current Organic Chemistry. 2023. Vol. 27. No. 15. pp. 1308-1318.
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TY - JOUR
DO - 10.2174/0113852728264519231006055100
UR - https://doi.org/10.2174/0113852728264519231006055100
TI - Medicinal Chemistry Aspects of Isoxazole Analogues as Anti-tubercular Agents
T2 - Current Organic Chemistry
AU - Singh, Harshwardhan
AU - Kumari, V.S. Anila
AU - Singh, Ankit Kumar
AU - Kumar, Adarsh
AU - Kumar, Pradeep
PY - 2023
DA - 2023/08/01
PB - Bentham Science Publishers Ltd.
SP - 1308-1318
IS - 15
VL - 27
SN - 1385-2728
SN - 1875-5348
ER -
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BibTex (up to 50 authors)
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@article{2023_Singh,
author = {Harshwardhan Singh and V.S. Anila Kumari and Ankit Kumar Singh and Adarsh Kumar and Pradeep Kumar},
title = {Medicinal Chemistry Aspects of Isoxazole Analogues as Anti-tubercular Agents},
journal = {Current Organic Chemistry},
year = {2023},
volume = {27},
publisher = {Bentham Science Publishers Ltd.},
month = {aug},
url = {https://doi.org/10.2174/0113852728264519231006055100},
number = {15},
pages = {1308--1318},
doi = {10.2174/0113852728264519231006055100}
}
Cite this
MLA
Copy
Singh, Harshwardhan, et al. “Medicinal Chemistry Aspects of Isoxazole Analogues as Anti-tubercular Agents.” Current Organic Chemistry, vol. 27, no. 15, Aug. 2023, pp. 1308-1318. https://doi.org/10.2174/0113852728264519231006055100.