Leishmanicidal and Trypanocidal Activity of Metal Complexes with 1,2,4-Triazolo[1,5-a]pyrimidines: Insights on their Therapeutic Potential against Leishmaniasis and Chagas Disease.
Тип публикации: Journal Article
Дата публикации: 2017-05-19
scimago Q2
wos Q2
БС1
SJR: 0.778
CiteScore: 7.7
Impact factor: 3.5
ISSN: 09298673, 1875533X
PubMed ID:
28521698
Organic Chemistry
Drug Discovery
Biochemistry
Pharmacology
Molecular Medicine
Краткое описание
Since their first synthesis back in the early 20th century, 1,2,4-triazolo[1,5- a]pyrimidines have aroused increasing interest in very diverse areas ranging from chemotherapy to agriculture or even photography. Their similarity to purines confers a potential bioactivity and this feature has been wisely exploited for therapeutic use, including antifungal, antipyretic, analgesic, antiinflammatory, antitumoral and antiparasitic properties. In this review, we focus on the compounds that these nitrogen heterocycles form with metal ions and their antiparasitic activity and therapeutic potential against two neglected diseases of tropical prevalence, leishmaniasis and Chagas disease.
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Salas J. et al. Leishmanicidal and Trypanocidal Activity of Metal Complexes with 1,2,4-Triazolo[1,5-a]pyrimidines: Insights on their Therapeutic Potential against Leishmaniasis and Chagas Disease. // Current Medicinal Chemistry. 2017. Vol. 24. No. 25.
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Salas J., Caballero A. B., Esteban-Parra G. M., Méndez-Arriaga J. M. Leishmanicidal and Trypanocidal Activity of Metal Complexes with 1,2,4-Triazolo[1,5-a]pyrimidines: Insights on their Therapeutic Potential against Leishmaniasis and Chagas Disease. // Current Medicinal Chemistry. 2017. Vol. 24. No. 25.
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TY - JOUR
DO - 10.2174/0929867324666170516122024
UR - https://doi.org/10.2174/0929867324666170516122024
TI - Leishmanicidal and Trypanocidal Activity of Metal Complexes with 1,2,4-Triazolo[1,5-a]pyrimidines: Insights on their Therapeutic Potential against Leishmaniasis and Chagas Disease.
T2 - Current Medicinal Chemistry
AU - Salas, Juan
AU - Caballero, Ana B.
AU - Esteban-Parra, Ginés M.
AU - Méndez-Arriaga, José M.
PY - 2017
DA - 2017/05/19
PB - Bentham Science Publishers Ltd.
IS - 25
VL - 24
PMID - 28521698
SN - 0929-8673
SN - 1875-533X
ER -
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BibTex (до 50 авторов)
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@article{2017_Salas,
author = {Juan Salas and Ana B. Caballero and Ginés M. Esteban-Parra and José M. Méndez-Arriaga},
title = {Leishmanicidal and Trypanocidal Activity of Metal Complexes with 1,2,4-Triazolo[1,5-a]pyrimidines: Insights on their Therapeutic Potential against Leishmaniasis and Chagas Disease.},
journal = {Current Medicinal Chemistry},
year = {2017},
volume = {24},
publisher = {Bentham Science Publishers Ltd.},
month = {may},
url = {https://doi.org/10.2174/0929867324666170516122024},
number = {25},
doi = {10.2174/0929867324666170516122024}
}