Imidazo[1,2-a]pyridine Scaffold as Prospective Therapeutic Agents
Publication type: Journal Article
Publication date: 2016-06-08
scimago Q2
wos Q3
SJR: 0.610
CiteScore: 6.4
Impact factor: 3.3
ISSN: 15680266, 18734294
PubMed ID:
27237332
Drug Discovery
General Medicine
Abstract
Imidazo[1,2-a]pyridine is one of the most potential bicyclic 5-6 heterocyclic rings that is recognized as a "drug prejudice" scaffold due to its broad range of applications in medicinal chemistry such as anticancer, antimycobacterial, antileishmanial, anticonvulsant, antimicrobial, antiviral, antidiabetic, proton pump inhibitor, insecticidal activities. This scaffold has also been represented in various marketed preparations such as zolimidine, zolpidem, alpidem. Therefore, several attempts were made to carry out the structural modifications of this scaffold to discover and develop novel therapeutic agents. This review provides a valuable insight into the research findings of wide range of derivatives of imidazo[1,2-a]pyridine scaffold leading to promising heterocyclic compounds which could be explored further for the synthesis of new derivatives as well as construction of potential drug-like chemical libraries for biological screening in search of new therapeutic agents.
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Total citations:
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Citations from 2025:
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(17.75%)
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GOST
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Deep A. et al. Imidazo[1,2-a]pyridine Scaffold as Prospective Therapeutic Agents // Current Topics in Medicinal Chemistry. 2016. Vol. 17. No. 2. pp. 238-250.
GOST all authors (up to 50)
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Deb P. K. Imidazo[1,2-a]pyridine Scaffold as Prospective Therapeutic Agents // Current Topics in Medicinal Chemistry. 2016. Vol. 17. No. 2. pp. 238-250.
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TY - JOUR
DO - 10.2174/1568026616666160530153233
UR - https://doi.org/10.2174/1568026616666160530153233
TI - Imidazo[1,2-a]pyridine Scaffold as Prospective Therapeutic Agents
T2 - Current Topics in Medicinal Chemistry
AU - Deb, Pran Kishore
PY - 2016
DA - 2016/06/08
PB - Bentham Science Publishers Ltd.
SP - 238-250
IS - 2
VL - 17
PMID - 27237332
SN - 1568-0266
SN - 1873-4294
ER -
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BibTex (up to 50 authors)
Copy
@article{2016_Deep,
author = {Pran Kishore Deb},
title = {Imidazo[1,2-a]pyridine Scaffold as Prospective Therapeutic Agents},
journal = {Current Topics in Medicinal Chemistry},
year = {2016},
volume = {17},
publisher = {Bentham Science Publishers Ltd.},
month = {jun},
url = {https://doi.org/10.2174/1568026616666160530153233},
number = {2},
pages = {238--250},
doi = {10.2174/1568026616666160530153233}
}
Cite this
MLA
Copy
Deep, Aakash, et al. “Imidazo[1,2-a]pyridine Scaffold as Prospective Therapeutic Agents.” Current Topics in Medicinal Chemistry, vol. 17, no. 2, Jun. 2016, pp. 238-250. https://doi.org/10.2174/1568026616666160530153233.
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