Recent Progress in 1H-1,2,3-triazoles as Potential Antifungal Agents
Publication type: Journal Article
Publication date: 2021-09-16
scimago Q2
wos Q3
SJR: 0.610
CiteScore: 6.4
Impact factor: 3.3
ISSN: 15680266, 18734294
PubMed ID:
34517801
Drug Discovery
General Medicine
Abstract
:
To overcome ever increasing cases of antifungal resistance and circumventing side effects and drug interactions related with currently available drugs has impelled the need to expedite the process of drug discovery and development of novel antifungals. 1,4-Disubstituted 1,2,3-triazole has gained tremendous interest in last two decades mainly because of its ease of synthesis via copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) and its broad spectrum of chemotherapeutic potential. 1,2,3-Triazole is an excellent pharmacophore which has been used as a bioisostere for obtaining libraries of new medicinally important scaffolds. The present review focus on the recent advances (2016-2021) of 1,2,3-triazole derivatives obtained by CuAAC as potential antifungal agents that may facilitate triazole based antifungal development process.
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Metrics
70
Total citations:
70
Citations from 2024:
39
(55.72%)
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GOST
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Poonia N. et al. Recent Progress in 1H-1,2,3-triazoles as Potential Antifungal Agents // Current Topics in Medicinal Chemistry. 2021. Vol. 21. No. 23. pp. 2109-2133.
GOST all authors (up to 50)
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Poonia N., Kumar A., Kumar V., Yadav M., Lal K. Recent Progress in 1H-1,2,3-triazoles as Potential Antifungal Agents // Current Topics in Medicinal Chemistry. 2021. Vol. 21. No. 23. pp. 2109-2133.
Cite this
RIS
Copy
TY - JOUR
DO - 10.2174/1568026621666210913122828
UR - https://doi.org/10.2174/1568026621666210913122828
TI - Recent Progress in 1H-1,2,3-triazoles as Potential Antifungal Agents
T2 - Current Topics in Medicinal Chemistry
AU - Poonia, Nisha
AU - Kumar, Aman
AU - Kumar, Vijay
AU - Yadav, Monika
AU - Lal, Kashmiri
PY - 2021
DA - 2021/09/16
PB - Bentham Science Publishers Ltd.
SP - 2109-2133
IS - 23
VL - 21
PMID - 34517801
SN - 1568-0266
SN - 1873-4294
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Poonia,
author = {Nisha Poonia and Aman Kumar and Vijay Kumar and Monika Yadav and Kashmiri Lal},
title = {Recent Progress in 1H-1,2,3-triazoles as Potential Antifungal Agents},
journal = {Current Topics in Medicinal Chemistry},
year = {2021},
volume = {21},
publisher = {Bentham Science Publishers Ltd.},
month = {sep},
url = {https://doi.org/10.2174/1568026621666210913122828},
number = {23},
pages = {2109--2133},
doi = {10.2174/1568026621666210913122828}
}
Cite this
MLA
Copy
Poonia, Nisha, et al. “Recent Progress in 1H-1,2,3-triazoles as Potential Antifungal Agents.” Current Topics in Medicinal Chemistry, vol. 21, no. 23, Sep. 2021, pp. 2109-2133. https://doi.org/10.2174/1568026621666210913122828.