Formulation of Lotion with Ethanol Extract of Curcuma manga Val. as UV B Sunscreen and Activity Test using UV-Vis Spectrophotometry

Nindya Kusumorini
Abdul Karim Zulkarnain
Publication typeJournal Article
Publication date2024-09-25
scimago Q3
wos Q4
SJR0.203
CiteScore1.4
Impact factor0.7
ISSN23389427, 23389486
Abstract

Temu mango (Curcuma manga Val) is a rhizome plant native to Indonesia that contains curcuminoid and flavonoid antioxidant compounds. These compounds are thought to have activity as UV light protectors, especially UV B. This study uses a qualitative test of the compound content in temu mango followed by formulation and activity testing of water in oil (w/o) sunscreen lotion of temu mango in vitro. Optimization of w/o lotion formulation uses Design Expert® (DE) software version 9.0.4.1 with the Simplex Lattice Design method. The DE software obtained 13 runs of w/o lotion formula and continued with physical properties evaluation to determine the optimum formula. The optimum formula of lotion w/o predicted by DE software was tested for physical stability for four weeks, SPF test, percent pigmentation, and percent erythema using UV-Vis spectrophotometry. The results of the study show that temu mango extract was found to provide an SPF value at a concentration of 0.3 mg/mL with an SPF value of 16.62. The results of the optimum formula of lotion w/o were 7%glycerin, 7% cera alba, 5% cetyl alcohol with a value of stickiness of 0.70 ± 0.03 seconds, spreadability of 13.20 ± 0.83 cm2, and viscosity of 95.19 ± 3.06 dPa.s. Referring to the storage results, the optimum formula of w/o lotion from temu mango extract was stable during one month of storage. The w/o lotion in the optimum formula produced an SPF value of 15.06 ± 0.39, percent erythema of 10.95%, and percent pigmentation of 10.41%.

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Kusumorini N., Zulkarnain A. K. Formulation of Lotion with Ethanol Extract of Curcuma manga Val. as UV B Sunscreen and Activity Test using UV-Vis Spectrophotometry // Indonesian Journal of Pharmacy. 2024.
GOST all authors (up to 50) Copy
Kusumorini N., Zulkarnain A. K. Formulation of Lotion with Ethanol Extract of Curcuma manga Val. as UV B Sunscreen and Activity Test using UV-Vis Spectrophotometry // Indonesian Journal of Pharmacy. 2024.
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TY - JOUR
DO - 10.22146/ijp.9583
UR - https://jurnal.ugm.ac.id/v3/IJP/article/view/9583
TI - Formulation of Lotion with Ethanol Extract of Curcuma manga Val. as UV B Sunscreen and Activity Test using UV-Vis Spectrophotometry
T2 - Indonesian Journal of Pharmacy
AU - Kusumorini, Nindya
AU - Zulkarnain, Abdul Karim
PY - 2024
DA - 2024/09/25
PB - Universitas Gadjah Mada
SN - 2338-9427
SN - 2338-9486
ER -
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@article{2024_Kusumorini,
author = {Nindya Kusumorini and Abdul Karim Zulkarnain},
title = {Formulation of Lotion with Ethanol Extract of Curcuma manga Val. as UV B Sunscreen and Activity Test using UV-Vis Spectrophotometry},
journal = {Indonesian Journal of Pharmacy},
year = {2024},
publisher = {Universitas Gadjah Mada},
month = {sep},
url = {https://jurnal.ugm.ac.id/v3/IJP/article/view/9583},
doi = {10.22146/ijp.9583}
}