Open Access
The glycoglycerolipid 1,2-dipalmitoyl-3-(N-palmitoyl-6′-amino-6′-deoxy-α-d -glucosyl)-sn-glycerol is no inhibitor of the human Myt1 kinase
Publication type: Journal Article
Publication date: 2014-06-18
scimago Q2
wos Q1
SJR: 0.857
CiteScore: 11.2
Impact factor: 5.4
ISSN: 14756366, 14756374
PubMed ID:
24939100
Drug Discovery
General Medicine
Pharmacology
Abstract
Previously, a glycoglycerolipid isolated from marine algae was reported to be a potent and selective inhibitor of the human Myt1 kinase, an enzyme involved in cell cycle regulation with great potential as an anti-cancer target. Based on that report, a lot of research effort has been invested by several working groups to synthesize and derivatize this compound. However, reliable assay data confirming the inhibitory potential and the mechanism of action of these glycoglycerolipids are missing so far. Here, based on experimental data and theoretical considerations, we show that the aforesaid glycoglycerolipid 1,2-dipalmitoyl-3-(N-palmitoyl-6'-amino-6'-deoxy-α-d-glucosyl)-sn-glycerol is not an inhibitor of the human Myt1 kinase.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
|
|
|
Endocrine-Related Cancer
1 publication, 33.33%
|
|
|
Cell Reports
1 publication, 33.33%
|
|
|
Bioorganic and Medicinal Chemistry
1 publication, 33.33%
|
|
|
1
|
Publishers
|
1
2
|
|
|
Elsevier
2 publications, 66.67%
|
|
|
Bioscientifica
1 publication, 33.33%
|
|
|
1
2
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
3
Total citations:
3
Citations from 2024:
0
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Rohe A. et al. The glycoglycerolipid 1,2-dipalmitoyl-3-(N-palmitoyl-6′-amino-6′-deoxy-α-d-glucosyl)-sn-glycerol is no inhibitor of the human Myt1 kinase // Journal of Enzyme Inhibition and Medicinal Chemistry. 2014. Vol. 30. No. 3. pp. 514-517.
GOST all authors (up to 50)
Copy
Rohe A., Göllner C., Erdmann F., Sippl W., Schmidt M. The glycoglycerolipid 1,2-dipalmitoyl-3-(N-palmitoyl-6′-amino-6′-deoxy-α-d-glucosyl)-sn-glycerol is no inhibitor of the human Myt1 kinase // Journal of Enzyme Inhibition and Medicinal Chemistry. 2014. Vol. 30. No. 3. pp. 514-517.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3109/14756366.2014.926343
UR - https://doi.org/10.3109/14756366.2014.926343
TI - The glycoglycerolipid 1,2-dipalmitoyl-3-(N-palmitoyl-6′-amino-6′-deoxy-α-d-glucosyl)-sn-glycerol is no inhibitor of the human Myt1 kinase
T2 - Journal of Enzyme Inhibition and Medicinal Chemistry
AU - Rohe, Alexander
AU - Göllner, Christiane
AU - Erdmann, Frank
AU - Sippl, Wolfgang
AU - Schmidt, M
PY - 2014
DA - 2014/06/18
PB - Taylor & Francis
SP - 514-517
IS - 3
VL - 30
PMID - 24939100
SN - 1475-6366
SN - 1475-6374
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2014_Rohe,
author = {Alexander Rohe and Christiane Göllner and Frank Erdmann and Wolfgang Sippl and M Schmidt},
title = {The glycoglycerolipid 1,2-dipalmitoyl-3-(N-palmitoyl-6′-amino-6′-deoxy-α-d-glucosyl)-sn-glycerol is no inhibitor of the human Myt1 kinase},
journal = {Journal of Enzyme Inhibition and Medicinal Chemistry},
year = {2014},
volume = {30},
publisher = {Taylor & Francis},
month = {jun},
url = {https://doi.org/10.3109/14756366.2014.926343},
number = {3},
pages = {514--517},
doi = {10.3109/14756366.2014.926343}
}
Cite this
MLA
Copy
Rohe, Alexander, et al. “The glycoglycerolipid 1,2-dipalmitoyl-3-(N-palmitoyl-6′-amino-6′-deoxy-α-d-glucosyl)-sn-glycerol is no inhibitor of the human Myt1 kinase.” Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 30, no. 3, Jun. 2014, pp. 514-517. https://doi.org/10.3109/14756366.2014.926343.