Open Access
Development of transferosomal gel for trans-dermal delivery of insulin using iodine complex
Тип публикации: Journal Article
Дата публикации: 2016-03-28
scimago Q1
wos Q1
БС1
SJR: 1.38
CiteScore: 16.4
Impact factor: 8.1
ISSN: 10717544, 15210464
PubMed ID:
27187718
General Medicine
Pharmaceutical Science
Краткое описание
The main object of this current research was to examine transferosomes as a transdermal delivery system for insulin, to overwhelm the difficulties related with its subcutaneous delivery. Transferosomal gel formulations were prepared by rotary evaporation sonication technique. The result revealed that insulin was successfully entrapped (78%) in optimized formulations (2.5 I.U. of the drug and 25% of sodium cholate) with cumulative percent drug release (83.11 ± 3.782). The glucose lowering study revealed that the transferosomal gel with chemical penetration enhancer showed better glucose lowering effect as compared to the control gel. Consequently, this study authenticated that the transferosomal gel can be used as a possible substitute to the conventional formulations of insulin with progressive permeation characteristics for transdermal application.
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Метрики
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ГОСТ |
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BibTex |
MLA
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ГОСТ
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Marwah H. et al. Development of transferosomal gel for trans-dermal delivery of insulin using iodine complex // Drug Delivery. 2016. Vol. 23. No. 5. pp. 1636-1644.
ГОСТ со всеми авторами (до 50)
Скопировать
Marwah H., Garg T., Rath G., Goyal A. K. Development of transferosomal gel for trans-dermal delivery of insulin using iodine complex // Drug Delivery. 2016. Vol. 23. No. 5. pp. 1636-1644.
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RIS
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TY - JOUR
DO - 10.3109/10717544.2016.1155243
UR - https://doi.org/10.3109/10717544.2016.1155243
TI - Development of transferosomal gel for trans-dermal delivery of insulin using iodine complex
T2 - Drug Delivery
AU - Marwah, Harneet
AU - Garg, Tarun
AU - Rath, Goutam
AU - Goyal, Amit Kumar
PY - 2016
DA - 2016/03/28
PB - Taylor & Francis
SP - 1636-1644
IS - 5
VL - 23
PMID - 27187718
SN - 1071-7544
SN - 1521-0464
ER -
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BibTex (до 50 авторов)
Скопировать
@article{2016_Marwah,
author = {Harneet Marwah and Tarun Garg and Goutam Rath and Amit Kumar Goyal},
title = {Development of transferosomal gel for trans-dermal delivery of insulin using iodine complex},
journal = {Drug Delivery},
year = {2016},
volume = {23},
publisher = {Taylor & Francis},
month = {mar},
url = {https://doi.org/10.3109/10717544.2016.1155243},
number = {5},
pages = {1636--1644},
doi = {10.3109/10717544.2016.1155243}
}
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MLA
Скопировать
Marwah, Harneet, et al. “Development of transferosomal gel for trans-dermal delivery of insulin using iodine complex.” Drug Delivery, vol. 23, no. 5, Mar. 2016, pp. 1636-1644. https://doi.org/10.3109/10717544.2016.1155243.