Open Access
Total Synthesis of (±)-Agastinol
Publication type: Journal Article
Publication date: 2011-06-01
scimago Q3
wos Q3
SJR: 0.306
CiteScore: 3.4
Impact factor: 1.2
ISSN: 03082342, 17475198, 20476507
General Chemistry
Abstract
A synthesis of the tetrahydrofuran lignan (±)-agastinol, starting from the cheap Vanillin, has been developed based on Stobbe reaction with diethyl succinate to give the skeleton of lignan, which was then reduced to afford meso- and threo-(±)-secoisolanciresinol. threo-(±)-Secoisolanciresinol was treated with DDQ in acetic acid to give the 2-aryl tetrahydrofuran lignan, and which was then condensed with ferulic acid to give (±)-agastinol for the first time.
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GOST
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Ding J. et al. Total Synthesis of (±)-Agastinol // Journal of Chemical Research. 2011. Vol. 35. No. 6. pp. 352-354.
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Ding J., Zhou H., Jiao B., Xia Y. Total Synthesis of (±)-Agastinol // Journal of Chemical Research. 2011. Vol. 35. No. 6. pp. 352-354.
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RIS
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TY - JOUR
DO - 10.3184/174751911x13082938433857
UR - https://doi.org/10.3184/174751911x13082938433857
TI - Total Synthesis of (±)-Agastinol
T2 - Journal of Chemical Research
AU - Ding, Junwei
AU - Zhou, Haitang
AU - Jiao, Bin
AU - Xia, Yamu
PY - 2011
DA - 2011/06/01
PB - SAGE
SP - 352-354
IS - 6
VL - 35
SN - 0308-2342
SN - 1747-5198
SN - 2047-6507
ER -
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BibTex (up to 50 authors)
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@article{2011_Ding,
author = {Junwei Ding and Haitang Zhou and Bin Jiao and Yamu Xia},
title = {Total Synthesis of (±)-Agastinol},
journal = {Journal of Chemical Research},
year = {2011},
volume = {35},
publisher = {SAGE},
month = {jun},
url = {https://doi.org/10.3184/174751911x13082938433857},
number = {6},
pages = {352--354},
doi = {10.3184/174751911x13082938433857}
}
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MLA
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Ding, Junwei, et al. “Total Synthesis of (±)-Agastinol.” Journal of Chemical Research, vol. 35, no. 6, Jun. 2011, pp. 352-354. https://doi.org/10.3184/174751911x13082938433857.