Search for neurophysiological mechanisms of configurational learning

Configural learning is a form of associative learning in which the conditioned stimulus is a holistic set of stimulus elements rather than individual stimuli or their isolated properties. Successfully solving the task of such associative learning requires a holistic analysis of the entire configuration as a whole. The ability to analyze not only individual physical aspects of a stimulus or single objects in a visual scene, but also their holistic combinations, offers significant evolutionary advantages, as configurations often have substantially greater predictive power compared to individual stimulus elements or features. Moreover, the ability to holistically analyze combinations of stimulus field elements or features can be considered an initial, primitive manifestation of consciousness. In the present review, we consider the history of the development of the concept of configural learning, the main methodological avenues of investigation, and currently available neurophysiological data on the putative neural basis of this phenomenon. We find it most interesting to study the processes of configural learning in humans using modern neuroimaging methods, as they provide a glimpse into the holistic brain functioning. Finally, we consider the future tasks aimed to provide a more complete understanding of the neurophysiology of the configural learning phenomenon.