Open Access
Synthesis and biological activity of 5-acetyl- and 5-hydroxyalkyl1,3-dioxane derivatives
Publication type: Journal Article
Publication date: 2023-10-08
scimago Q4
SJR: 0.214
CiteScore: 1.5
Impact factor: —
ISSN: 24106593, 26867575
Organic Chemistry
Inorganic Chemistry
Process Chemistry and Technology
Fluid Flow and Transfer Processes
Abstract
Objectives. To synthesize derivatives of 5-acetyl- and 5-hydroxyalkyl-1,3-dioxanes and evaluate their effect on platelet aggregation and plasma hemostasis.
Methods. To determine the qualitative and quantitative composition of the reaction masses, gas chromatography-, chromate mass spectrometry-, and 1H and 13C nuclear magnetic resonance spectrometry methods were used.
Results. Derivatives of 5-acetyl- and 5-hydroxyalkyl-1,3-dioxanes were obtained under thermal heating conditions in order to evaluate their effect on platelet aggregation and plasma hemostasis.
Conclusions. Derivatives of 5-acetyl- and 5-hydroxyalkyl-1,3-dioxanes were synthesized in high yields. Their effect on platelet aggregation and plasma hemostasis was established.
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Musin A. I. et al. Synthesis and biological activity of 5-acetyl- and 5-hydroxyalkyl1,3-dioxane derivatives // Fine Chemical Technologies. 2023. Vol. 18. No. 4. pp. 381-391.
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Musin A. I., Borisova Y. G., Dzhumaev S. S., Khusnutdinova N. S., Raskil’dina G. Z., Sultanova R., Zlotskii S. Synthesis and biological activity of 5-acetyl- and 5-hydroxyalkyl1,3-dioxane derivatives // Fine Chemical Technologies. 2023. Vol. 18. No. 4. pp. 381-391.
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TY - JOUR
DO - 10.32362/2410-6593-2023-18-4-381-391
UR - https://doi.org/10.32362/2410-6593-2023-18-4-381-391
TI - Synthesis and biological activity of 5-acetyl- and 5-hydroxyalkyl1,3-dioxane derivatives
T2 - Fine Chemical Technologies
AU - Musin, A I
AU - Borisova, Yu. G.
AU - Dzhumaev, Sh. Sh.
AU - Khusnutdinova, N S
AU - Raskil’dina, G. Z.
AU - Sultanova, Rimma
AU - Zlotskii, Simon
PY - 2023
DA - 2023/10/08
PB - RTU MIREA
SP - 381-391
IS - 4
VL - 18
SN - 2410-6593
SN - 2686-7575
ER -
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BibTex (up to 50 authors)
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@article{2023_Musin,
author = {A I Musin and Yu. G. Borisova and Sh. Sh. Dzhumaev and N S Khusnutdinova and G. Z. Raskil’dina and Rimma Sultanova and Simon Zlotskii},
title = {Synthesis and biological activity of 5-acetyl- and 5-hydroxyalkyl1,3-dioxane derivatives},
journal = {Fine Chemical Technologies},
year = {2023},
volume = {18},
publisher = {RTU MIREA},
month = {oct},
url = {https://doi.org/10.32362/2410-6593-2023-18-4-381-391},
number = {4},
pages = {381--391},
doi = {10.32362/2410-6593-2023-18-4-381-391}
}
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MLA
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Musin, A. I., et al. “Synthesis and biological activity of 5-acetyl- and 5-hydroxyalkyl1,3-dioxane derivatives.” Fine Chemical Technologies, vol. 18, no. 4, Oct. 2023, pp. 381-391. https://doi.org/10.32362/2410-6593-2023-18-4-381-391.