Acta Naturae
,  том 7 ,  издание 4 ,  страницы 142-145

2-(2,4-Dioxy-1,2,3,4-Tetrahydropyrimidin-1-yl)-N-(4-Phenoxyphenyl)-Acetamides as a Novel Class of Cytomegalovirus Replication Inhibitors

Тип публикации: Journal Article
Дата публикации: 2015-12-15
Включен в RSCI
scimago Q2
wos Q4
БС1
SJR: 0.633
CiteScore: 3.4
Impact factor: 2
ISSN: 20758251, 20758243
Biochemistry
Molecular Biology
Molecular Medicine
Biotechnology
Краткое описание

A series of novel uracil derivatives, bearing N-(4-phenoxyphenyl)acetamide moiety at N3 of a pyrimidine ring, has been synthesized. Their antiviral activity has been evaluated. It has been found that the novel compounds possess high inhibitory activity against replication of human cytomegalovirus (AD-169 and Davis strains) in HEL cell cultures. In addition, some of the derivatives proved to be inhibitory against varicella zoster virus.

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Chemistry of Heterocyclic Compounds
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Chemistry of Heterocyclic Compounds
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Mendeleev Communications
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Babkov D. A. et al. 2-(2,4-Dioxy-1,2,3,4-Tetrahydropyrimidin-1-yl)-N-(4-Phenoxyphenyl)-Acetamides as a Novel Class of Cytomegalovirus Replication Inhibitors // Acta Naturae. 2015. Vol. 7. No. 4. pp. 142-145.
ГОСТ со всеми авторами (до 50) Скопировать
Babkov D. A., Paramonova M. P., Ozerov A., Khandazhinskaya A. L., Snoeck R., Andrei G., Novikov M. 2-(2,4-Dioxy-1,2,3,4-Tetrahydropyrimidin-1-yl)-N-(4-Phenoxyphenyl)-Acetamides as a Novel Class of Cytomegalovirus Replication Inhibitors // Acta Naturae. 2015. Vol. 7. No. 4. pp. 142-145.
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TY - JOUR
DO - 10.32607/20758251-2015-7-4-142-145
UR - https://doi.org/10.32607/20758251-2015-7-4-142-145
TI - 2-(2,4-Dioxy-1,2,3,4-Tetrahydropyrimidin-1-yl)-N-(4-Phenoxyphenyl)-Acetamides as a Novel Class of Cytomegalovirus Replication Inhibitors
T2 - Acta Naturae
AU - Babkov, D A
AU - Paramonova, M P
AU - Ozerov, A.A.
AU - Khandazhinskaya, A L
AU - Snoeck, R.
AU - Andrei, G.
AU - Novikov, M.S.
PY - 2015
DA - 2015/12/15
PB - Acta Naturae Ltd
SP - 142-145
IS - 4
VL - 7
SN - 2075-8251
SN - 2075-8243
ER -
BibTex |
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@article{2015_Babkov,
author = {D A Babkov and M P Paramonova and A.A. Ozerov and A L Khandazhinskaya and R. Snoeck and G. Andrei and M.S. Novikov},
title = {2-(2,4-Dioxy-1,2,3,4-Tetrahydropyrimidin-1-yl)-N-(4-Phenoxyphenyl)-Acetamides as a Novel Class of Cytomegalovirus Replication Inhibitors},
journal = {Acta Naturae},
year = {2015},
volume = {7},
publisher = {Acta Naturae Ltd},
month = {dec},
url = {https://doi.org/10.32607/20758251-2015-7-4-142-145},
number = {4},
pages = {142--145},
doi = {10.32607/20758251-2015-7-4-142-145}
}
MLA
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Babkov, D. A., et al. “2-(2,4-Dioxy-1,2,3,4-Tetrahydropyrimidin-1-yl)-N-(4-Phenoxyphenyl)-Acetamides as a Novel Class of Cytomegalovirus Replication Inhibitors.” Acta Naturae, vol. 7, no. 4, Dec. 2015, pp. 142-145. https://doi.org/10.32607/20758251-2015-7-4-142-145.