Combined Method for Treating Orophynary Cancer

Purpose: To demonstrate the possibility of a combined approach in the treatment of a patient with locally advanced squamous cell carcinoma of the nasopharynx, complicated by massive erosive bleeding using endovascular embolization, proton therapy and targeted therapy. Material and methods: The Federal Scientific Research Center for Reconstruction and Research has developed a method of a combined approach to the treatment of patients with malignant neoplasms of the nasopharynx, during which endovascular embolization and proton beam therapy in combination with targeted therapy are consistently used. Results: A set of sequential treatment procedures and drug administration allowed us to eliminate life-threatening bleeding, normalize the patient’s general condition, conduct a course of proton radiation therapy for a patient with locally advanced squamous cell carcinoma of the nasopharynx, complicated by massive bleeding, and achieve stable local control over the process. Conclusion: The use of the described tactics in the treatment of tumors of the nasopharynx and oral cavity allows in a short period to move from urgent endovascular occlusion of bleeding vessels to the stages of special antitumor treatment, providing a combined approach to the treatment of head and neck tumors.