Open Access
,
volume 15
Quantitative Methods for the Detection of Tau Seeding Activity in Human Biofluids
Publication type: Journal Article
Publication date: 2021-03-19
scimago Q2
wos Q2
SJR: 1.068
CiteScore: 6.6
Impact factor: 3.2
ISSN: 16624548, 1662453X
PubMed ID:
33828458
General Neuroscience
Abstract
The ability of tau aggregates to recruit and misfold monomeric tau and propagate across brain regions has been studied extensively and is now recognized as a critical pathological step in Alzheimer’s disease (AD) and other tauopathies. Recent evidence suggests that the detection of tau seeds in human samples may be relevant and correlate with clinical data. Here, we review the available methods for the measurement of such tau seeds, their limitations and their potential implementation for the development of the next-generation biomarkers.
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GOST
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Lathuiliere A. et al. Quantitative Methods for the Detection of Tau Seeding Activity in Human Biofluids // Frontiers in Neuroscience. 2021. Vol. 15.
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Lathuiliere A., Hyman B. T. Quantitative Methods for the Detection of Tau Seeding Activity in Human Biofluids // Frontiers in Neuroscience. 2021. Vol. 15.
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TY - JOUR
DO - 10.3389/fnins.2021.654176
UR - https://doi.org/10.3389/fnins.2021.654176
TI - Quantitative Methods for the Detection of Tau Seeding Activity in Human Biofluids
T2 - Frontiers in Neuroscience
AU - Lathuiliere, Aurelien
AU - Hyman, Bradley T.
PY - 2021
DA - 2021/03/19
PB - Frontiers Media S.A.
VL - 15
PMID - 33828458
SN - 1662-4548
SN - 1662-453X
ER -
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BibTex (up to 50 authors)
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@article{2021_Lathuiliere,
author = {Aurelien Lathuiliere and Bradley T. Hyman},
title = {Quantitative Methods for the Detection of Tau Seeding Activity in Human Biofluids},
journal = {Frontiers in Neuroscience},
year = {2021},
volume = {15},
publisher = {Frontiers Media S.A.},
month = {mar},
url = {https://doi.org/10.3389/fnins.2021.654176},
doi = {10.3389/fnins.2021.654176}
}