Open Access
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Ferroptosis is a new therapeutic target for spinal cord injury

Xin-yue Bai 1
Xiao-long Liu 1
Zhi-Zhong Deng 1
Dong Min Wei 1
Die Zhang 1
Hui-Lin Xi 1
Qing-Yan Wang 1
Meng-Ze He 1
Yan-Ling Yang 1
1
 
School of Medicine, Yan’an University, China
Publication typeJournal Article
Publication date2023-03-14
scimago Q2
wos Q2
SJR1.068
CiteScore6.6
Impact factor3.2
ISSN16624548, 1662453X
General Neuroscience
Abstract

Spinal cord injury is a serious traumatic disease. As Ferroptosis has been increasingly studied in recent years, it has been found to be closely related to the pathophysiological processes of spinal cord injury. Iron overload, reactive oxygen species accumulation, lipid peroxidation and glutamate accumulation associated with Ferroptosis are all present in spinal cord injury, and thus Ferroptosis is thought to be involved in the pathological processes secondary to spinal cord injury. This article highlights the relationship between Ferroptosis and spinal cord injury, lists substances that improve spinal cord injury by inhibiting Ferroptosis, and concludes with a discussion of the problems that may be encountered in the clinical translation of Ferroptosis inhibitors as a means of enabling their faster use in clinical treatment.

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GOST |
Cite this
GOST Copy
Bai X. et al. Ferroptosis is a new therapeutic target for spinal cord injury // Frontiers in Neuroscience. 2023. Vol. 17.
GOST all authors (up to 50) Copy
Bai X., Liu X., Deng Z., Wei D. M., Zhang D., Xi H., Wang Q., He M., Yang Y. Ferroptosis is a new therapeutic target for spinal cord injury // Frontiers in Neuroscience. 2023. Vol. 17.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.3389/fnins.2023.1136143
UR - https://doi.org/10.3389/fnins.2023.1136143
TI - Ferroptosis is a new therapeutic target for spinal cord injury
T2 - Frontiers in Neuroscience
AU - Bai, Xin-yue
AU - Liu, Xiao-long
AU - Deng, Zhi-Zhong
AU - Wei, Dong Min
AU - Zhang, Die
AU - Xi, Hui-Lin
AU - Wang, Qing-Yan
AU - He, Meng-Ze
AU - Yang, Yan-Ling
PY - 2023
DA - 2023/03/14
PB - Frontiers Media S.A.
VL - 17
PMID - 36998732
SN - 1662-4548
SN - 1662-453X
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2023_Bai,
author = {Xin-yue Bai and Xiao-long Liu and Zhi-Zhong Deng and Dong Min Wei and Die Zhang and Hui-Lin Xi and Qing-Yan Wang and Meng-Ze He and Yan-Ling Yang},
title = {Ferroptosis is a new therapeutic target for spinal cord injury},
journal = {Frontiers in Neuroscience},
year = {2023},
volume = {17},
publisher = {Frontiers Media S.A.},
month = {mar},
url = {https://doi.org/10.3389/fnins.2023.1136143},
doi = {10.3389/fnins.2023.1136143}
}