Open Access
,
volume 13
Hemorrhagic fever viruses: Pathogenesis, therapeutics, and emerging and re-emerging potential
Lizdany Flórez-Álvarez
1
,
Edmarcia Elisa De Souza
1
,
Viviane Fongaro Botosso
2
,
Danielle Bruna Leal De Oliveira
3
,
Paulo Lee Ho
2
,
Carlos Pelleschi Taborda
1
,
Giuseppe Palmisano
1
,
Margareth Lara Capurro
1
,
João Renato Rebello Pinho
3, 4
,
Helena Lage Ferreira
5
,
Paola Minoprio
6
,
Eurico Arruda
7
,
Luís Carlos de Souza Ferreira
1, 6
,
Carsten Wrenger
1
,
Edison Luiz Durigon
1, 6
3
Albert Einstein Institute for Teaching and Research (IIEP), Hospital Israelita Albert Einstein, Brazil
|
Publication type: Journal Article
Publication date: 2022-10-25
scimago Q1
wos Q1
SJR: 1.172
CiteScore: 8.5
Impact factor: 4.5
ISSN: 1664302X
PubMed ID:
36386719
Microbiology (medical)
Microbiology
Abstract
Hemorrhagic fever viruses (HFVs) pose a threat to global public health owing to the emergence and re-emergence of highly fatal diseases. Viral hemorrhagic fevers (VHFs) caused by these viruses are mostly characterized by an acute febrile syndrome with coagulation abnormalities and generalized hemorrhage that may lead to life-threatening organ dysfunction. Currently, the events underlying the viral pathogenicity associated with multiple organ dysfunction syndrome still underexplored. In this minireview, we address the current knowledge of the mechanisms underlying VHFs pathogenesis and discuss the available development of preventive and therapeutic options to treat these infections. Furthermore, we discuss the potential of HFVs to cause worldwide emergencies along with factors that favor their spread beyond their original niches.
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Metrics
29
Total citations:
29
Citations from 2024:
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(79.31%)
Cite this
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RIS |
BibTex
Cite this
GOST
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Flórez-Álvarez L. et al. Hemorrhagic fever viruses: Pathogenesis, therapeutics, and emerging and re-emerging potential // Frontiers in Microbiology. 2022. Vol. 13.
GOST all authors (up to 50)
Copy
Flórez-Álvarez L., De Souza E. E., Botosso V. F., De Oliveira D. B. L., Ho P., Taborda C. P., Palmisano G., Capurro M. L., Pinho J. R. R., Ferreira H. L., Minoprio P., Arruda E., de Souza Ferreira L. C., Wrenger C., Durigon E. L. Hemorrhagic fever viruses: Pathogenesis, therapeutics, and emerging and re-emerging potential // Frontiers in Microbiology. 2022. Vol. 13.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3389/fmicb.2022.1040093
UR - https://doi.org/10.3389/fmicb.2022.1040093
TI - Hemorrhagic fever viruses: Pathogenesis, therapeutics, and emerging and re-emerging potential
T2 - Frontiers in Microbiology
AU - Flórez-Álvarez, Lizdany
AU - De Souza, Edmarcia Elisa
AU - Botosso, Viviane Fongaro
AU - De Oliveira, Danielle Bruna Leal
AU - Ho, Paulo Lee
AU - Taborda, Carlos Pelleschi
AU - Palmisano, Giuseppe
AU - Capurro, Margareth Lara
AU - Pinho, João Renato Rebello
AU - Ferreira, Helena Lage
AU - Minoprio, Paola
AU - Arruda, Eurico
AU - de Souza Ferreira, Luís Carlos
AU - Wrenger, Carsten
AU - Durigon, Edison Luiz
PY - 2022
DA - 2022/10/25
PB - Frontiers Media S.A.
VL - 13
PMID - 36386719
SN - 1664-302X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2022_Flórez-Álvarez,
author = {Lizdany Flórez-Álvarez and Edmarcia Elisa De Souza and Viviane Fongaro Botosso and Danielle Bruna Leal De Oliveira and Paulo Lee Ho and Carlos Pelleschi Taborda and Giuseppe Palmisano and Margareth Lara Capurro and João Renato Rebello Pinho and Helena Lage Ferreira and Paola Minoprio and Eurico Arruda and Luís Carlos de Souza Ferreira and Carsten Wrenger and Edison Luiz Durigon},
title = {Hemorrhagic fever viruses: Pathogenesis, therapeutics, and emerging and re-emerging potential},
journal = {Frontiers in Microbiology},
year = {2022},
volume = {13},
publisher = {Frontiers Media S.A.},
month = {oct},
url = {https://doi.org/10.3389/fmicb.2022.1040093},
doi = {10.3389/fmicb.2022.1040093}
}