Open Access
Open access
Applied Sciences (Switzerland), volume 12, issue 6, pages 3080

Modern and Dedicated Methods for Producing Molecularly Imprinted Polymer Layers in Sensing Applications

Ana Mihaela Gavrila 1
Elena Bianca Stoica 1
Tanta Verona Iordache 1
Andrei Sarbu 1
1
 
Advanced Polymer Materials and Polymer Recycling Group, The National Institute for Research & Development in Chemistry and Petrochemistry ICECHIM, Splaiul Independentei no. 202, 060021 Bucharest, Romania
Publication typeJournal Article
Publication date2022-03-17
scimago Q2
wos Q2
SJR0.508
CiteScore5.3
Impact factor2.5
ISSN20763417
Computer Science Applications
Process Chemistry and Technology
General Materials Science
Instrumentation
General Engineering
Fluid Flow and Transfer Processes
Abstract

Molecular imprinting (MI) is the most available and known method to produce artificial recognition sites, similar to antibodies, inside or at the surface of a polymeric material. For this reason, scholars all over the world have found MI appealing, thus developing, in this past period, various types of molecularly imprinted polymers (MIPs) that can be applied to a wide range of applications, including catalysis, separation sciences and monitoring/diagnostic devices for chemicals, biochemicals and pharmaceuticals. For instance, the advantages brought by the use of MIPs in the sensing and analytics field refer to higher selectivity, sensitivity and low detection limits, but also to higher chemical and thermal stability as well as reusability. In light of recent literature findings, this review presents both modern and dedicated methods applied to produce MIP layers that can be integrated with existent detection systems. In this respect, the following MI methods to produce sensing layers are presented and discussed: surface polymerization, electropolymerization, sol–gel derived techniques, phase inversionand deposition of electroactive pastes/inks that include MIP particles.

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