Open Access
Intraoperative Creation of Tissue-Engineered Grafts with Minimally Manipulated Cells: New Concept of Bone Tissue Engineering In Situ
Olga A Krasilnikova
1
,
Denis S. Baranovskii
1, 2
,
Anna Yakimova
1
,
Nadezhda Arguchinskaya
1
,
Anastas Kisel
1
,
Dmitry Sosin
3
,
Yana Sulina
4
,
Sergey A. Ivanov
1
,
Peter V. Shegay
1
,
Andrey D. Kaprin
1, 2
,
Ilya Klabukov
1, 2, 5
Publication type: Journal Article
Publication date: 2022-11-17
PubMed ID:
36421105
Bioengineering
Abstract
Transfer of regenerative approaches into clinical practice is limited by strict legal regulation of in vitro expanded cells and risks associated with substantial manipulations. Isolation of cells for the enrichment of bone grafts directly in the Operating Room appears to be a promising solution for the translation of biomedical technologies into clinical practice. These intraoperative approaches could be generally characterized as a joint concept of tissue engineering in situ. Our review covers techniques of intraoperative cell isolation and seeding for the creation of tissue-engineered grafts in situ, that is, directly in the Operating Room. Up-to-date, the clinical use of tissue-engineered grafts created in vitro remains a highly inaccessible option. Fortunately, intraoperative tissue engineering in situ is already available for patients who need advanced treatment modalities.
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22
Total citations:
22
Citations from 2024:
16
(72%)
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GOST
Copy
Krasilnikova O. A. et al. Intraoperative Creation of Tissue-Engineered Grafts with Minimally Manipulated Cells: New Concept of Bone Tissue Engineering In Situ // Bioengineering. 2022. Vol. 9. No. 11. p. 704.
GOST all authors (up to 50)
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Krasilnikova O. A., Baranovskii D. S., Yakimova A., Arguchinskaya N., Kisel A., Sosin D., Sulina Y., Ivanov S. A., Shegay P. V., Kaprin A. D., Klabukov I. Intraoperative Creation of Tissue-Engineered Grafts with Minimally Manipulated Cells: New Concept of Bone Tissue Engineering In Situ // Bioengineering. 2022. Vol. 9. No. 11. p. 704.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/bioengineering9110704
UR - https://doi.org/10.3390/bioengineering9110704
TI - Intraoperative Creation of Tissue-Engineered Grafts with Minimally Manipulated Cells: New Concept of Bone Tissue Engineering In Situ
T2 - Bioengineering
AU - Krasilnikova, Olga A
AU - Baranovskii, Denis S.
AU - Yakimova, Anna
AU - Arguchinskaya, Nadezhda
AU - Kisel, Anastas
AU - Sosin, Dmitry
AU - Sulina, Yana
AU - Ivanov, Sergey A.
AU - Shegay, Peter V.
AU - Kaprin, Andrey D.
AU - Klabukov, Ilya
PY - 2022
DA - 2022/11/17
PB - MDPI
SP - 704
IS - 11
VL - 9
PMID - 36421105
SN - 2306-5354
ER -
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BibTex (up to 50 authors)
Copy
@article{2022_Krasilnikova,
author = {Olga A Krasilnikova and Denis S. Baranovskii and Anna Yakimova and Nadezhda Arguchinskaya and Anastas Kisel and Dmitry Sosin and Yana Sulina and Sergey A. Ivanov and Peter V. Shegay and Andrey D. Kaprin and Ilya Klabukov},
title = {Intraoperative Creation of Tissue-Engineered Grafts with Minimally Manipulated Cells: New Concept of Bone Tissue Engineering In Situ},
journal = {Bioengineering},
year = {2022},
volume = {9},
publisher = {MDPI},
month = {nov},
url = {https://doi.org/10.3390/bioengineering9110704},
number = {11},
pages = {704},
doi = {10.3390/bioengineering9110704}
}
Cite this
MLA
Copy
Krasilnikova, Olga A., et al. “Intraoperative Creation of Tissue-Engineered Grafts with Minimally Manipulated Cells: New Concept of Bone Tissue Engineering In Situ.” Bioengineering, vol. 9, no. 11, Nov. 2022, p. 704. https://doi.org/10.3390/bioengineering9110704.