Open Access
Open access
volume 15 issue 5 pages 639

Secure Hybrid Deep Learning for MRI-Based Brain Tumor Detection in Smart Medical IoT Systems

Nermeen Gamal Rezk 1
Samah Alshathri 2
Amged Sayed 3, 4
Ezz El-Din Hemdan 5, 6
Heba El-Behery 1
Publication typeJournal Article
Publication date2025-03-06
scimago Q2
wos Q1
SJR0.773
CiteScore5.9
Impact factor3.3
ISSN20754418
Abstract

Background/Objectives: Brain tumors are among the most aggressive diseases, significantly contributing to human mortality. Typically, the classification of brain tumors is performed through a biopsy, which is often delayed until brain surgery is necessary. An automated image classification technique is crucial for accelerating diagnosis, reducing the need for invasive procedures and minimizing the risk of manual diagnostic errors being made by radiologists. Additionally, the security of sensitive MRI images remains a major concern, with robust encryption methods required to protect patient data from unauthorized access and breaches in Medical Internet of Things (MIoT) systems. Methods: This study proposes a secure and automated MRI image classification system that integrates chaotic and Arnold encryption techniques with hybrid deep learning models using VGG16 and a deep neural network (DNN). The methodology ensures MRI image confidentiality while enabling the accurate classification of brain tumors and not compromising performance. Results: The proposed system demonstrated a high classification performance under both encryption scenarios. For chaotic encryption, it achieved an accuracy of 93.75%, precision of 94.38%, recall of 93.75%, and an F-score of 93.67%. For Arnold encryption, the model attained an accuracy of 94.1%, precision of 96.9%, recall of 94.1%, and an F-score of 96.6%. These results indicate that encrypted images can still be effectively classified, ensuring both security and diagnostic accuracy. Conclusions: The proposed hybrid deep learning approach provides a secure, accurate, and efficient solution for brain tumor detection in MIoT-based healthcare applications. By encrypting MRI images before classification, the system ensures patient data confidentiality while maintaining high diagnostic performance. This approach can empower radiologists and healthcare professionals worldwide, enabling early and secure brain tumor diagnosis without the need for invasive procedures.

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GOST Copy
Rezk N. G. et al. Secure Hybrid Deep Learning for MRI-Based Brain Tumor Detection in Smart Medical IoT Systems // Diagnostics. 2025. Vol. 15. No. 5. p. 639.
GOST all authors (up to 50) Copy
Rezk N. G., Alshathri S., Sayed A., Hemdan E. E., El-Behery H. Secure Hybrid Deep Learning for MRI-Based Brain Tumor Detection in Smart Medical IoT Systems // Diagnostics. 2025. Vol. 15. No. 5. p. 639.
RIS |
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RIS Copy
TY - JOUR
DO - 10.3390/diagnostics15050639
UR - https://www.mdpi.com/2075-4418/15/5/639
TI - Secure Hybrid Deep Learning for MRI-Based Brain Tumor Detection in Smart Medical IoT Systems
T2 - Diagnostics
AU - Rezk, Nermeen Gamal
AU - Alshathri, Samah
AU - Sayed, Amged
AU - Hemdan, Ezz El-Din
AU - El-Behery, Heba
PY - 2025
DA - 2025/03/06
PB - MDPI
SP - 639
IS - 5
VL - 15
SN - 2075-4418
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2025_Rezk,
author = {Nermeen Gamal Rezk and Samah Alshathri and Amged Sayed and Ezz El-Din Hemdan and Heba El-Behery},
title = {Secure Hybrid Deep Learning for MRI-Based Brain Tumor Detection in Smart Medical IoT Systems},
journal = {Diagnostics},
year = {2025},
volume = {15},
publisher = {MDPI},
month = {mar},
url = {https://www.mdpi.com/2075-4418/15/5/639},
number = {5},
pages = {639},
doi = {10.3390/diagnostics15050639}
}
MLA
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MLA Copy
Rezk, Nermeen Gamal, et al. “Secure Hybrid Deep Learning for MRI-Based Brain Tumor Detection in Smart Medical IoT Systems.” Diagnostics, vol. 15, no. 5, Mar. 2025, p. 639. https://www.mdpi.com/2075-4418/15/5/639.