Open Access
Open access
том 24 издание 19 страницы 14951

MOTS-c Serum Concentration Positively Correlates with Lower-Body Muscle Strength and Is Not Related to Maximal Oxygen Uptake—A Preliminary Study

Remigiusz A Domin 1, 2
Michał J Pytka 2, 3
Mikołaj Żołyński 2, 3
Jan Niziński 2
Przemyslaw Guzik 2, 3
Jacek Zielinski 5
Тип публикацииJournal Article
Дата публикации2023-10-06
scimago Q1
wos Q1
БС1
SJR1.273
CiteScore9.0
Impact factor4.9
ISSN16616596, 14220067
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Molecular Biology
General Medicine
Краткое описание

The mitochondrial open reading frame of 12S rRNA-c (MOTS-c) is a mitochondrial-derived peptide that regulates the nuclear genome during stressful conditions such as hypoxia, which is typical of exercise and training. We aim to mainly investigate the relationship between serum MOTS-c concentration and muscle strength parameters measured during the countermovement jump test with oxygen consumption (VO2) measured during the cardiopulmonary exercise test to exhaustion. Physically active healthy volunteers (17 male, three female, median age 30 years), not involved in any regular exercise program or participating in any sports competitions, performed five consecutive countermovement jump tests and cardiopulmonary exercise tests until maximal exhaustion and underwent a body composition assessment by means of bioelectrical impedance analysis, and had serum MOTS-c concentration measured at rest. Serum MOTS-c concentration was positively correlated with the average power and average and maximal force of the jumps, both overall muscle mass and leg muscle mass, but not with body fat percentage. There was no correlation with peak VO2. A higher serum MOTS-c concentration is associated with greater muscle mass, force, and power generated during jumping in healthy individuals but not exercise capacity reflected by peak VO2. More studies are needed to better understand the physiological and clinical values of these findings and why MOTS-c is better associated with measures of muscle strength and not endurance in physically active people.

Найдено 
Найдено 

Топ-30

Журналы

1
Trends in Genetics
1 публикация, 20%
Journal of Hematology and Oncology
1 публикация, 20%
Sleep and Biological Rhythms
1 публикация, 20%
Redox Biology
1 публикация, 20%
Life Sciences
1 публикация, 20%
1

Издатели

1
2
3
Elsevier
3 публикации, 60%
Springer Nature
2 публикации, 40%
1
2
3
  • Мы не учитываем публикации, у которых нет DOI.
  • Статистика публикаций обновляется еженедельно.

Вы ученый?

Создайте профиль, чтобы получать персональные рекомендации коллег, конференций и новых статей.
Метрики
5
Поделиться
Цитировать
ГОСТ |
Цитировать
Domin R. A. et al. MOTS-c Serum Concentration Positively Correlates with Lower-Body Muscle Strength and Is Not Related to Maximal Oxygen Uptake—A Preliminary Study // International Journal of Molecular Sciences. 2023. Vol. 24. No. 19. p. 14951.
ГОСТ со всеми авторами (до 50) Скопировать
Domin R. A., Pytka M. J., Żołyński M., Niziński J., Ruciński M., Guzik P., Zielinski J., Ruchała M. MOTS-c Serum Concentration Positively Correlates with Lower-Body Muscle Strength and Is Not Related to Maximal Oxygen Uptake—A Preliminary Study // International Journal of Molecular Sciences. 2023. Vol. 24. No. 19. p. 14951.
RIS |
Цитировать
TY - JOUR
DO - 10.3390/ijms241914951
UR - https://doi.org/10.3390/ijms241914951
TI - MOTS-c Serum Concentration Positively Correlates with Lower-Body Muscle Strength and Is Not Related to Maximal Oxygen Uptake—A Preliminary Study
T2 - International Journal of Molecular Sciences
AU - Domin, Remigiusz A
AU - Pytka, Michał J
AU - Żołyński, Mikołaj
AU - Niziński, Jan
AU - Ruciński, Marcin
AU - Guzik, Przemyslaw
AU - Zielinski, Jacek
AU - Ruchała, Marek
PY - 2023
DA - 2023/10/06
PB - MDPI
SP - 14951
IS - 19
VL - 24
PMID - 37834399
SN - 1661-6596
SN - 1422-0067
ER -
BibTex |
Цитировать
BibTex (до 50 авторов) Скопировать
@article{2023_Domin,
author = {Remigiusz A Domin and Michał J Pytka and Mikołaj Żołyński and Jan Niziński and Marcin Ruciński and Przemyslaw Guzik and Jacek Zielinski and Marek Ruchała},
title = {MOTS-c Serum Concentration Positively Correlates with Lower-Body Muscle Strength and Is Not Related to Maximal Oxygen Uptake—A Preliminary Study},
journal = {International Journal of Molecular Sciences},
year = {2023},
volume = {24},
publisher = {MDPI},
month = {oct},
url = {https://doi.org/10.3390/ijms241914951},
number = {19},
pages = {14951},
doi = {10.3390/ijms241914951}
}
MLA
Цитировать
Domin, Remigiusz A., et al. “MOTS-c Serum Concentration Positively Correlates with Lower-Body Muscle Strength and Is Not Related to Maximal Oxygen Uptake—A Preliminary Study.” International Journal of Molecular Sciences, vol. 24, no. 19, Oct. 2023, p. 14951. https://doi.org/10.3390/ijms241914951.