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,  volume 2022 ,  issue 3 ,  pages M1434

Methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetate

Publication type: Journal Article
Publication date: 2022-08-25
MDPI
scimago Q4
wos Q4
SJR: 0.142
CiteScore: 0.9
Impact factor: 0.4
ISSN: 14228599
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract

A green synthetic procedure was developed for the two-step synthesis of methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetate from anthranilic acid, using two green chemistry approaches: utilization of the DES and microwave-induced synthesis. The first step includes a synthesis of 2-mercapto-3-(3-methoxyphenyl)quinazolin-4(3H)-one which was performed in choline chloride:urea DES. In the second step S-alkylation of 2-mercapto-3-(3-methoxyphenyl)quinazolin-4(3H)-one was performed in a microwave-induced reaction. The desired compound was successfully obtained in a yield of 59% and was characterized by different spectral methods.

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Molnar M., Komar M., Jerković I. Methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetate // MolBank. 2022. Vol. 2022. No. 3. p. M1434.
GOST all authors (up to 50) Copy
Molnar M., Komar M., Jerković I. Methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetate // MolBank. 2022. Vol. 2022. No. 3. p. M1434.
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RIS Copy
TY - JOUR
DO - 10.3390/m1434
UR - https://doi.org/10.3390/m1434
TI - Methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetate
T2 - MolBank
AU - Molnar, Maja
AU - Komar, Mario
AU - Jerković, Igor
PY - 2022
DA - 2022/08/25
PB - MDPI
SP - M1434
IS - 3
VL - 2022
SN - 1422-8599
ER -
BibTex |
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@article{2022_Molnar,
author = {Maja Molnar and Mario Komar and Igor Jerković},
title = {Methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetate},
journal = {MolBank},
year = {2022},
volume = {2022},
publisher = {MDPI},
month = {aug},
url = {https://doi.org/10.3390/m1434},
number = {3},
pages = {M1434},
doi = {10.3390/m1434}
}
MLA
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Molnar, Maja, et al. “Methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetate.” MolBank, vol. 2022, no. 3, Aug. 2022, p. M1434. https://doi.org/10.3390/m1434.