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,  том 2023 ,  издание 1 ,  страницы M1564

Cis-(3-benzyloxy-1,1-cyclobutanedicarboxylato κ2O,O′)bis(1-methyl-1H-pyrazole)platinum(II)

Тип публикации: Journal Article
Дата публикации: 2023-01-23
MDPI
scimago Q4
wos Q4
БС4
SJR: 0.142
CiteScore: 0.9
Impact factor: 0.4
ISSN: 14228599
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Краткое описание

A huge variety of types of cancer makes it necessary to search for new effective drugs with a defined molecular target. Modification of substituents in ligands based on 3-hydroxy-1,1-cyclobutanedicarboxylic acid are one of the effective directions to design a better version of carboplatin. In the present study, we combined in one molecule a derivative of 3-hydroxycyclobutane-1,1-dicarboxylic acid and N-methylpyrazole as a carrier ligand. The antiproliferative of the novel complex Pt(II) was established for cell lines HCT116, MCF7, A549, and WI38 by means of a standard MTT colorimetric assay.

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Pavlova A. S. et al. Cis-(3-benzyloxy-1,1-cyclobutanedicarboxylato κ2O,O′)bis(1-methyl-1H-pyrazole)platinum(II) // MolBank. 2023. Vol. 2023. No. 1. p. M1564.
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Pavlova A. S., Buslaev D. A., Borisova N. E., Temnov V. V., Nazarov A. A., Podrugina T. A. Cis-(3-benzyloxy-1,1-cyclobutanedicarboxylato κ2O,O′)bis(1-methyl-1H-pyrazole)platinum(II) // MolBank. 2023. Vol. 2023. No. 1. p. M1564.
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TY - JOUR
DO - 10.3390/m1564
UR - https://doi.org/10.3390/m1564
TI - Cis-(3-benzyloxy-1,1-cyclobutanedicarboxylato κ2O,O′)bis(1-methyl-1H-pyrazole)platinum(II)
T2 - MolBank
AU - Pavlova, Anna S.
AU - Buslaev, Daniil A.
AU - Borisova, Nataliya E.
AU - Temnov, Victor V.
AU - Nazarov, Alexey A.
AU - Podrugina, Tatyana A.
PY - 2023
DA - 2023/01/23
PB - MDPI
SP - M1564
IS - 1
VL - 2023
SN - 1422-8599
ER -
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@article{2023_Pavlova,
author = {Anna S. Pavlova and Daniil A. Buslaev and Nataliya E. Borisova and Victor V. Temnov and Alexey A. Nazarov and Tatyana A. Podrugina},
title = {Cis-(3-benzyloxy-1,1-cyclobutanedicarboxylato κ2O,O′)bis(1-methyl-1H-pyrazole)platinum(II)},
journal = {MolBank},
year = {2023},
volume = {2023},
publisher = {MDPI},
month = {jan},
url = {https://doi.org/10.3390/m1564},
number = {1},
pages = {M1564},
doi = {10.3390/m1564}
}
MLA
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Pavlova, Anna S., et al. “Cis-(3-benzyloxy-1,1-cyclobutanedicarboxylato κ2O,O′)bis(1-methyl-1H-pyrazole)platinum(II).” MolBank, vol. 2023, no. 1, Jan. 2023, p. M1564. https://doi.org/10.3390/m1564.