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MolBank, volume 2023, issue 3, pages M1700

4-(2,5-Dimethyl-1H-pyrrol-1-yl)-1,2,5-oxadiazol-3-amine

Publication type: Journal Article
Publication date: 2023-07-20
Journal: MolBank
Quartile SCImago
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Impact factor: 0.4
ISSN: 14228599
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract

1,2,5-Oxadiazol-3-amines with a heterocyclic substituent in the 4-position are being intensively investigated as compounds with valuable pharmacological activity. In this communication, the reaction of 1,2,5-oxadiazole-3,4-diamine with 2,5-hexanedione was shown to selectively give 4-(2,5-dimethyl-1H-pyrrol-1-yl)-1,2,5-oxadiazol-3-amine as a product of the Paal–Knorr reaction. The structure of the synthesized compound was established by elemental analysis, high-resolution mass spectrometry, 1H and 13C NMR, and IR spectroscopy.

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Obruchnikova N. V., Rakitin O. A. 4-(2,5-Dimethyl-1H-pyrrol-1-yl)-1,2,5-oxadiazol-3-amine // MolBank. 2023. Vol. 2023. No. 3. p. M1700.
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Obruchnikova N. V., Rakitin O. A. 4-(2,5-Dimethyl-1H-pyrrol-1-yl)-1,2,5-oxadiazol-3-amine // MolBank. 2023. Vol. 2023. No. 3. p. M1700.
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TY - JOUR
DO - 10.3390/m1700
UR - https://doi.org/10.3390/m1700
TI - 4-(2,5-Dimethyl-1H-pyrrol-1-yl)-1,2,5-oxadiazol-3-amine
T2 - MolBank
AU - Obruchnikova, Natalia V.
AU - Rakitin, Oleg A.
PY - 2023
DA - 2023/07/20 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - M1700
IS - 3
VL - 2023
SN - 1422-8599
ER -
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@article{2023_Obruchnikova,
author = {Natalia V. Obruchnikova and Oleg A. Rakitin},
title = {4-(2,5-Dimethyl-1H-pyrrol-1-yl)-1,2,5-oxadiazol-3-amine},
journal = {MolBank},
year = {2023},
volume = {2023},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {jul},
url = {https://doi.org/10.3390/m1700},
number = {3},
pages = {M1700},
doi = {10.3390/m1700}
}
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Obruchnikova, Natalia V., and Oleg A. Rakitin. “4-(2,5-Dimethyl-1H-pyrrol-1-yl)-1,2,5-oxadiazol-3-amine.” MolBank, vol. 2023, no. 3, Jul. 2023, p. M1700. https://doi.org/10.3390/m1700.
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