Biocompatible Hydrotalcite Nanohybrids for Medical Functions
Biocompatible hydrotalcite nanohybrids, i.e., layered double hydroxide (LDH) based nanohybrids have attracted significant attention for biomedical functions. Benefiting from good biocompatibility, tailored drug incorporation, high drug loading capacity, targeted cellular delivery and natural pH-responsive biodegradability, hydrotalcite nanohybrids have shown great potential in drug/gene delivery, cancer therapy and bio-imaging. This review aims to summarize recent progress of hydrotalcite nanohybrids, including the history of the hydrotalcite-like compounds for application in the medical field, synthesis, functionalization, physicochemical properties, cytotoxicity, cellular uptake mechanism, as well as their related applications in biomedicine. The potential and challenges will also be discussed for further development of LDHs both as drug delivery carriers and diagnostic agents.
Top-30
Journals
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Pharmaceutics
3 publications, 7.69%
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Nanomaterials
3 publications, 7.69%
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Materials
2 publications, 5.13%
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International Journal of Biological Macromolecules
1 publication, 2.56%
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Pharmaceuticals
1 publication, 2.56%
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Molecules
1 publication, 2.56%
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Scientific Reports
1 publication, 2.56%
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Environmental Science and Pollution Research
1 publication, 2.56%
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European Physical Journal Plus
1 publication, 2.56%
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Journal of the Korean Ceramic Society
1 publication, 2.56%
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Polymer Bulletin
1 publication, 2.56%
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Journal of Drug Delivery Science and Technology
1 publication, 2.56%
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Applied Clay Science
1 publication, 2.56%
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Journal of Pharmaceutical Sciences
1 publication, 2.56%
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International Journal on Interactive Design and Manufacturing
1 publication, 2.56%
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Journal of Controlled Release
1 publication, 2.56%
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Ceramics International
1 publication, 2.56%
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Green Chemistry
1 publication, 2.56%
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ACS Applied Nano Materials
1 publication, 2.56%
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Environmental Research
1 publication, 2.56%
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ACS Sustainable Chemistry and Engineering
1 publication, 2.56%
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FlatChem
1 publication, 2.56%
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Chemical Engineering Journal
1 publication, 2.56%
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Pharmaceutical Research
1 publication, 2.56%
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Advanced Science
1 publication, 2.56%
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MethodsX
1 publication, 2.56%
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Journal of Hazardous Materials
1 publication, 2.56%
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Acta Pharmaceutica Sinica B
1 publication, 2.56%
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Science of the Total Environment
1 publication, 2.56%
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Publishers
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Elsevier
15 publications, 38.46%
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MDPI
10 publications, 25.64%
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Springer Nature
6 publications, 15.38%
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American Chemical Society (ACS)
3 publications, 7.69%
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Wiley
2 publications, 5.13%
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Korean Ceramic Society
1 publication, 2.56%
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Royal Society of Chemistry (RSC)
1 publication, 2.56%
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IntechOpen
1 publication, 2.56%
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- We do not take into account publications without a DOI.
- Statistics recalculated weekly.