Open Access
Pharmaceuticals, volume 14, issue 4, pages 354
An Overview of the Biological Activity of Pyrrolo[3,4-c]pyridine Derivatives
1
Department of Pharmaceutical Technology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wrocław, Poland
|
2
Department of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland
|
Publication type: Journal Article
Publication date: 2021-04-11
Journal:
Pharmaceuticals
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor: 4.6
ISSN: 14248247, 14248247
Drug Discovery
Pharmaceutical Science
Molecular Medicine
Abstract
Pyrrolo[3,4-c]pyridine is one of the six structural isomers of the bicyclic ring system containing a pyrrole moiety fused to a pyridine nucleus. The broad spectrum of pharmacological properties of pyrrolo[3,4-c]pyridine derivatives is the main reason for developing new compounds containing this scaffold. This review presents studies on the biological activity of pyrrolo[3,4-c]pyridines that have been reported in the scientific literature. Most of these derivatives have been studied as analgesic and sedative agents. Biological investigations have shown that pyrrolo[3,4-c]pyridines can be used to treat diseases of the nervous and immune systems. Their antidiabetic, antimycobacterial, antiviral, and antitumor activities also have been found.
Citations by journals
1
2
|
|
Future Medicinal Chemistry
2 publications, 8.33%
|
|
Beilstein Journal of Organic Chemistry
1 publication, 4.17%
|
|
Acta Crystallographica Section E: Crystallographic Communications
1 publication, 4.17%
|
|
International Journal of Molecular Sciences
1 publication, 4.17%
|
|
Catalysts
1 publication, 4.17%
|
|
Molecules
1 publication, 4.17%
|
|
Molecular Diversity
1 publication, 4.17%
|
|
Journal of Ethnopharmacology
1 publication, 4.17%
|
|
Journal of Molecular Structure
1 publication, 4.17%
|
|
Journal of Coordination Chemistry
1 publication, 4.17%
|
|
Journal of Agricultural and Food Chemistry
1 publication, 4.17%
|
|
Physical Sciences Reviews
1 publication, 4.17%
|
|
Asian Journal of Chemistry
1 publication, 4.17%
|
|
Current Organic Synthesis
1 publication, 4.17%
|
|
Bioorganic Chemistry
1 publication, 4.17%
|
|
Letters in Organic Chemistry
1 publication, 4.17%
|
|
Russian Journal of General Chemistry
1 publication, 4.17%
|
|
Current Topics in Medicinal Chemistry
1 publication, 4.17%
|
|
Tetrahedron
1 publication, 4.17%
|
|
Chemistry of Heterocyclic Compounds
1 publication, 4.17%
|
|
ChemistrySelect
1 publication, 4.17%
|
|
Pharmacia
1 publication, 4.17%
|
|
1
2
|
Citations by publishers
1
2
3
4
|
|
Elsevier
4 publications, 16.67%
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
3 publications, 12.5%
|
|
Bentham Science
3 publications, 12.5%
|
|
Springer Nature
2 publications, 8.33%
|
|
Future Medicine
2 publications, 8.33%
|
|
Beilstein-Institut
1 publication, 4.17%
|
|
International Union of Crystallography (IUCr)
1 publication, 4.17%
|
|
Taylor & Francis
1 publication, 4.17%
|
|
American Chemical Society (ACS)
1 publication, 4.17%
|
|
Walter de Gruyter
1 publication, 4.17%
|
|
Asian Journal of Chemistry
1 publication, 4.17%
|
|
Pleiades Publishing
1 publication, 4.17%
|
|
Wiley
1 publication, 4.17%
|
|
Pensoft Publishers
1 publication, 4.17%
|
|
1
2
3
4
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2021,2022,2023,2024],"ids":[0,0,0,0],"codes":[0,0,0,0],"imageUrls":["","","",""],"datasets":[{"label":"Citations number","data":[3,9,9,3],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["12.5","37.5","37.5","12.5"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Future Medicinal Chemistry","Beilstein Journal of Organic Chemistry","Acta Crystallographica Section E: Crystallographic Communications","International Journal of Molecular Sciences","Catalysts","Molecules","Molecular Diversity","Journal of Ethnopharmacology","Journal of Molecular Structure","Journal of Coordination Chemistry","Journal of Agricultural and Food Chemistry","Physical Sciences Reviews","Asian Journal of Chemistry","Current Organic Synthesis","Bioorganic Chemistry","Letters in Organic Chemistry","Russian Journal of General Chemistry","Current Topics in Medicinal Chemistry","Tetrahedron","Chemistry of Heterocyclic Compounds","ChemistrySelect","Pharmacia"],"ids":[22201,21928,7164,14627,3739,1770,9362,13298,9347,23053,22576,3644,22412,20129,4196,24363,13581,3277,3439,16828,8021,5284],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/AN2jnDN59NmKaS4CWLHAGstADL2DbnatQScsFA6C_medium.webp","\/storage\/images\/resized\/ex6KJoZujZOZFZh7jGfeHauiftuB3CI7iwJVFRDg_medium.webp","\/storage\/images\/resized\/xG3oC19920mmFVqkoVEGKGaMCeoalzyvWxPkVox5_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/5YZtvLvkPZuc2JHOaZsjCvGSHFCuC3drUwN3YAc5_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/3SpVxcYL33bOvPq4sHxJLH2NeKNeDloahSUpNiO4_medium.webp","\/storage\/images\/resized\/Vb3hw5ha3GXFySkcFIRq7hedUzMGRVNprYvOwnlQ_medium.webp","\/storage\/images\/resized\/doUaFUZdxUEQjLi1TwZjGHi8HXYNWWSk04dSC6Xh_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/doUaFUZdxUEQjLi1TwZjGHi8HXYNWWSk04dSC6Xh_medium.webp","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","\/storage\/images\/resized\/doUaFUZdxUEQjLi1TwZjGHi8HXYNWWSk04dSC6Xh_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/b6G9vjk5CDda677dGbshycMePIiAXuDS2ebcYaBQ_medium.webp"],"datasets":[{"label":"","data":[2,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[8.33,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Elsevier","Multidisciplinary Digital Publishing Institute (MDPI)","Bentham Science","Springer Nature","Future Medicine","Beilstein-Institut","International Union of Crystallography (IUCr)","Taylor & Francis","American Chemical Society (ACS)","Walter de Gruyter","Asian Journal of Chemistry","Pleiades Publishing","Wiley","Pensoft Publishers"],"ids":[17,202,39,8,6949,6139,730,18,40,4,6264,101,11,1086],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/doUaFUZdxUEQjLi1TwZjGHi8HXYNWWSk04dSC6Xh_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/AN2jnDN59NmKaS4CWLHAGstADL2DbnatQScsFA6C_medium.webp","\/storage\/images\/resized\/ex6KJoZujZOZFZh7jGfeHauiftuB3CI7iwJVFRDg_medium.webp","\/storage\/images\/resized\/xG3oC19920mmFVqkoVEGKGaMCeoalzyvWxPkVox5_medium.webp","\/storage\/images\/resized\/5YZtvLvkPZuc2JHOaZsjCvGSHFCuC3drUwN3YAc5_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/3SpVxcYL33bOvPq4sHxJLH2NeKNeDloahSUpNiO4_medium.webp","\/storage\/images\/resized\/Vb3hw5ha3GXFySkcFIRq7hedUzMGRVNprYvOwnlQ_medium.webp","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/b6G9vjk5CDda677dGbshycMePIiAXuDS2ebcYaBQ_medium.webp"],"datasets":[{"label":"","data":[4,3,3,2,2,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[16.67,12.5,12.5,8.33,8.33,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17,4.17],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Wójcicka A., Redzicka A. An Overview of the Biological Activity of Pyrrolo[3,4-c]pyridine Derivatives // Pharmaceuticals. 2021. Vol. 14. No. 4. p. 354.
GOST all authors (up to 50)
Copy
Wójcicka A., Redzicka A. An Overview of the Biological Activity of Pyrrolo[3,4-c]pyridine Derivatives // Pharmaceuticals. 2021. Vol. 14. No. 4. p. 354.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/ph14040354
UR - https://doi.org/10.3390/ph14040354
TI - An Overview of the Biological Activity of Pyrrolo[3,4-c]pyridine Derivatives
T2 - Pharmaceuticals
AU - Wójcicka, Anna
AU - Redzicka, Aleksandra
PY - 2021
DA - 2021/04/11 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 354
IS - 4
VL - 14
SN - 1424-8247
SN - 1424-8247
ER -
Cite this
BibTex
Copy
@article{2021_Wójcicka,
author = {Anna Wójcicka and Aleksandra Redzicka},
title = {An Overview of the Biological Activity of Pyrrolo[3,4-c]pyridine Derivatives},
journal = {Pharmaceuticals},
year = {2021},
volume = {14},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {apr},
url = {https://doi.org/10.3390/ph14040354},
number = {4},
pages = {354},
doi = {10.3390/ph14040354}
}
Cite this
MLA
Copy
Wójcicka, Anna, and Aleksandra Redzicka. “An Overview of the Biological Activity of Pyrrolo[3,4-c]pyridine Derivatives.” Pharmaceuticals, vol. 14, no. 4, Apr. 2021, p. 354. https://doi.org/10.3390/ph14040354.