Open Access
Biologically Active Metabolites from the Marine Sediment-Derived Fungus Aspergillus flocculosus
Тип публикации: Journal Article
Дата публикации: 2019-10-11
scimago Q1
wos Q1
БС1
SJR: 1.030
CiteScore: 10.1
Impact factor: 5.4
ISSN: 16603397
PubMed ID:
31614563
Drug Discovery
Pharmaceutical Science
Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
Краткое описание
Four new compounds were isolated from the Vietnamese marine sediment-derived fungus Aspergillus flocculosus, one aspyrone-related polyketide aspilactonol G (2), one meroterpenoid 12-epi-aspertetranone D (4), two drimane derivatives (7,9), together with five known metabolites (1,3,5,6,8,10). The structures of compounds 1–10 were established by NMR and MS techniques. The absolute stereoconfigurations of compounds 1 and 2 were determined by a modified Mosher’s method. The absolute configurations of compounds 4 and 7 were established by a combination of analysis of ROESY data and coupling constants as well as biogenetic considerations. Compounds 7 and 8 exhibited cytotoxic activity toward human prostate cancer 22Rv1, human breast cancer MCF-7, and murine neuroblastoma Neuro-2a cells.
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ГОСТ
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Yurchenko A. N. et al. Biologically Active Metabolites from the Marine Sediment-Derived Fungus Aspergillus flocculosus // Marine Drugs. 2019. Vol. 17. No. 10. p. 579.
ГОСТ со всеми авторами (до 50)
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Yurchenko A. N., Trinh P. T. H., Girich (ivanets) E., Smetanina O., Rasin A., Popov R., Dyshlovoy S. A., von Amsberg G., Menchinskaya E., Tran T. V., Afiyatullov S. Biologically Active Metabolites from the Marine Sediment-Derived Fungus Aspergillus flocculosus // Marine Drugs. 2019. Vol. 17. No. 10. p. 579.
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RIS
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TY - JOUR
DO - 10.3390/MD17100579
UR - https://doi.org/10.3390/MD17100579
TI - Biologically Active Metabolites from the Marine Sediment-Derived Fungus Aspergillus flocculosus
T2 - Marine Drugs
AU - Yurchenko, Anton N
AU - Trinh, Phan Thi Hoai
AU - Girich (ivanets), Elena
AU - Smetanina, Olga
AU - Rasin, Anton
AU - Popov, Roman
AU - Dyshlovoy, Sergey A.
AU - von Amsberg, Gunhild
AU - Menchinskaya, Ekaterina
AU - Tran, Thanh Van
AU - Afiyatullov, Shamil
PY - 2019
DA - 2019/10/11
PB - MDPI
SP - 579
IS - 10
VL - 17
PMID - 31614563
SN - 1660-3397
ER -
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BibTex (до 50 авторов)
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@article{2019_Yurchenko,
author = {Anton N Yurchenko and Phan Thi Hoai Trinh and Elena Girich (ivanets) and Olga Smetanina and Anton Rasin and Roman Popov and Sergey A. Dyshlovoy and Gunhild von Amsberg and Ekaterina Menchinskaya and Thanh Van Tran and Shamil Afiyatullov},
title = {Biologically Active Metabolites from the Marine Sediment-Derived Fungus Aspergillus flocculosus},
journal = {Marine Drugs},
year = {2019},
volume = {17},
publisher = {MDPI},
month = {oct},
url = {https://doi.org/10.3390/MD17100579},
number = {10},
pages = {579},
doi = {10.3390/MD17100579}
}
Цитировать
MLA
Скопировать
Yurchenko, Anton N., et al. “Biologically Active Metabolites from the Marine Sediment-Derived Fungus Aspergillus flocculosus.” Marine Drugs, vol. 17, no. 10, Oct. 2019, p. 579. https://doi.org/10.3390/MD17100579.
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