Open Access
Regulation of Cancer Metastasis by TRAIL/Death Receptor Signaling
Publication type: Journal Article
Publication date: 2021-03-26
PubMed ID:
33810241
Biochemistry
Molecular Biology
Abstract
Death ligands such as tumor necrosis factor-related apoptosis-inducing ligand (TRAIL; TNFSF10) and their corresponding death receptors (e.g., DR5) not only initiate apoptosis through activation of the extrinsic apoptotic pathway but also exert non-apoptotic biological functions such as regulation of inflammation and cancer metastasis. The involvement of the TRAIL/death receptor signaling pathway in the regulation of cancer invasion and metastasis is complex as both positive and negative roles have been reported. The underlying molecular mechanisms are even more complicated. This review will focus on discussing current knowledge in our understanding of the involvement of TRAIL/death receptor-mediated signaling in the regulation of cancer cell invasion and metastasis.
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Total citations:
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Citations from 2024:
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(54%)
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MLA
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GOST
Copy
Oh Y., Sun S. Regulation of Cancer Metastasis by TRAIL/Death Receptor Signaling // Biomolecules. 2021. Vol. 11. No. 4. p. 499.
GOST all authors (up to 50)
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Oh Y., Sun S. Regulation of Cancer Metastasis by TRAIL/Death Receptor Signaling // Biomolecules. 2021. Vol. 11. No. 4. p. 499.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/biom11040499
UR - https://doi.org/10.3390/biom11040499
TI - Regulation of Cancer Metastasis by TRAIL/Death Receptor Signaling
T2 - Biomolecules
AU - Oh, You-Take
AU - Sun, Shi-Yong
PY - 2021
DA - 2021/03/26
PB - MDPI
SP - 499
IS - 4
VL - 11
PMID - 33810241
SN - 2218-273X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Oh,
author = {You-Take Oh and Shi-Yong Sun},
title = {Regulation of Cancer Metastasis by TRAIL/Death Receptor Signaling},
journal = {Biomolecules},
year = {2021},
volume = {11},
publisher = {MDPI},
month = {mar},
url = {https://doi.org/10.3390/biom11040499},
number = {4},
pages = {499},
doi = {10.3390/biom11040499}
}
Cite this
MLA
Copy
Oh, You-Take, and Shi-Yong Sun. “Regulation of Cancer Metastasis by TRAIL/Death Receptor Signaling.” Biomolecules, vol. 11, no. 4, Mar. 2021, p. 499. https://doi.org/10.3390/biom11040499.