Open Access
Open access
MDPI
Biosensors
,  volume 15 ,  issue 5 ,  pages 296

Carbon Nanotube-Based Field-Effect Transistor Biosensors for Biomedical Applications: Decadal Developments and Advancements (2016–2025)

Publication type: Journal Article
Publication date: 2025-05-07
MDPI
scimago Q1
wos Q1
SJR: 0.885
CiteScore: 9.8
Impact factor: 5.6
ISSN: 20796374, 0265928X
Abstract

Advancements in carbon nanotube-based FET (CNT-FET) biosensors from 2016 to 2025 have boosted their sensitivity, specificity, and rapid detection performance for biomedical purposes. This review highlights key innovations in transducer materials, functionalization strategies, and device architectures, including floating-gate CNT-FETs for detecting cancer biomarkers, infectious disease antigens, and neurodegenerative disease markers. Novel approaches, such as dual-microfluidic field-effect biosensor (dual-MFB) structures and carboxylated graphene quantum dot (cGQD) coupling, have further expanded their diagnostic potential. Despite significant progress, challenges in scalability, reproducibility, and long-term stability remain. Overall, this work highlights the transformative potential of CNT-FET biosensors while outlining a roadmap for translating laboratory innovations into practical, high-impact biomedical applications.

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Sengupta J., Hussain C. M. Carbon Nanotube-Based Field-Effect Transistor Biosensors for Biomedical Applications: Decadal Developments and Advancements (2016–2025) // Biosensors. 2025. Vol. 15. No. 5. p. 296.
GOST all authors (up to 50) Copy
Sengupta J., Hussain C. M. Carbon Nanotube-Based Field-Effect Transistor Biosensors for Biomedical Applications: Decadal Developments and Advancements (2016–2025) // Biosensors. 2025. Vol. 15. No. 5. p. 296.
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TY - JOUR
DO - 10.3390/bios15050296
UR - https://www.mdpi.com/2079-6374/15/5/296
TI - Carbon Nanotube-Based Field-Effect Transistor Biosensors for Biomedical Applications: Decadal Developments and Advancements (2016–2025)
T2 - Biosensors
AU - Sengupta, Joydip
AU - Hussain, Chaudhery Mustansar
PY - 2025
DA - 2025/05/07
PB - MDPI
SP - 296
IS - 5
VL - 15
SN - 2079-6374
SN - 0265-928X
ER -
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@article{2025_Sengupta,
author = {Joydip Sengupta and Chaudhery Mustansar Hussain},
title = {Carbon Nanotube-Based Field-Effect Transistor Biosensors for Biomedical Applications: Decadal Developments and Advancements (2016–2025)},
journal = {Biosensors},
year = {2025},
volume = {15},
publisher = {MDPI},
month = {may},
url = {https://www.mdpi.com/2079-6374/15/5/296},
number = {5},
pages = {296},
doi = {10.3390/bios15050296}
}
MLA
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Sengupta, Joydip, and Chaudhery Mustansar Hussain. “Carbon Nanotube-Based Field-Effect Transistor Biosensors for Biomedical Applications: Decadal Developments and Advancements (2016–2025).” Biosensors, vol. 15, no. 5, May. 2025, p. 296. https://www.mdpi.com/2079-6374/15/5/296.