Open Access
Single-Chain Fragment Variable: Recent Progress in Cancer Diagnosis and Therapy
Тип публикации: Journal Article
Дата публикации: 2022-08-30
PubMed ID:
36077739
Cancer Research
Oncology
Краткое описание
Cancer remains a public health problem worldwide. Although conventional therapies have led to some excellent outcomes, some patients fail to respond to treatment, they have few therapeutic alternatives and a poor survival prognosis. Several strategies have been proposed to overcome this issue. The most recent approach is immunotherapy, particularly the use of recombinant antibodies and their derivatives, such as the single-chain fragment variable (scFv) containing the complete antigen-binding domains of a whole antibody that successfully targets tumor cells. This review describes the recent progress made with scFvs as a cancer diagnostic and therapeutic tool, with an emphasis on preclinical approaches and their potential use in clinical trials.
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Метрики
72
Всего цитирований:
72
Цитирований c 2025:
30
(42.25%)
Цитировать
ГОСТ |
RIS |
BibTex |
MLA
Цитировать
ГОСТ
Скопировать
Muñoz López P. et al. Single-Chain Fragment Variable: Recent Progress in Cancer Diagnosis and Therapy // Cancers. 2022. Vol. 14. No. 17. p. 4206.
ГОСТ со всеми авторами (до 50)
Скопировать
Muñoz López P., Ribas-Aparicio R. M., Becerra Báez E. I., Fraga Pérez K., Flores Martínez L. F., Mateos Chávez A. A., Luria-Pérez R. Single-Chain Fragment Variable: Recent Progress in Cancer Diagnosis and Therapy // Cancers. 2022. Vol. 14. No. 17. p. 4206.
Цитировать
RIS
Скопировать
TY - JOUR
DO - 10.3390/cancers14174206
UR - https://doi.org/10.3390/cancers14174206
TI - Single-Chain Fragment Variable: Recent Progress in Cancer Diagnosis and Therapy
T2 - Cancers
AU - Muñoz López, Paola
AU - Ribas-Aparicio, Rosa María
AU - Becerra Báez, Elayne Irene
AU - Fraga Pérez, Karla
AU - Flores Martínez, Luis Fernando
AU - Mateos Chávez, Armando Alfredo
AU - Luria-Pérez, Rosendo
PY - 2022
DA - 2022/08/30
PB - MDPI
SP - 4206
IS - 17
VL - 14
PMID - 36077739
SN - 2072-6694
ER -
Цитировать
BibTex (до 50 авторов)
Скопировать
@article{2022_Muñoz López,
author = {Paola Muñoz López and Rosa María Ribas-Aparicio and Elayne Irene Becerra Báez and Karla Fraga Pérez and Luis Fernando Flores Martínez and Armando Alfredo Mateos Chávez and Rosendo Luria-Pérez},
title = {Single-Chain Fragment Variable: Recent Progress in Cancer Diagnosis and Therapy},
journal = {Cancers},
year = {2022},
volume = {14},
publisher = {MDPI},
month = {aug},
url = {https://doi.org/10.3390/cancers14174206},
number = {17},
pages = {4206},
doi = {10.3390/cancers14174206}
}
Цитировать
MLA
Скопировать
Muñoz López, Paola, et al. “Single-Chain Fragment Variable: Recent Progress in Cancer Diagnosis and Therapy.” Cancers, vol. 14, no. 17, Aug. 2022, p. 4206. https://doi.org/10.3390/cancers14174206.